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    Cardiovascular Risk Event Prediction and Uses Thereof
    1.
    发明申请
    Cardiovascular Risk Event Prediction and Uses Thereof 审中-公开

    公开(公告)号：US20200166523A1

    公开(公告)日：2020-05-28

    申请号：US16751102

    申请日：2020-01-23

    Applicant: SomaLogic, Inc.

    Inventor： Rosalynn Dianne GILL ,  Stephen Alaric WILLIAMS ,  Alec A.E. STEWART ,  Robert MEHLER ,  Trudi FOREMAN ,  Britta SINGER

    IPC: G01N33/68

    Abstract: The present disclosure includes biomarkers, methods, devices, reagents, systems, and kits for the evaluation of risk of a caradiovascular (CV) Event within 5 years. In one aspect, the disclosure provides biomarkers that can be used alone or in various combinations to evaluate risk of a CV event within 5 years. In another aspect, methods are provided for evaluating risk of a CV event within 5 years in an individual, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 1. In a further aspect, methods are provided for evaluating the risk of a CV, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 2. In a further aspect, methods are provided for evaluating the risk of a CV event in an individual, generally within 5 years, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 3.

    Cardiovascular Risk Event Prediction and Uses Thereof
    2.
    发明申请
    Cardiovascular Risk Event Prediction and Uses Thereof 审中-公开
    心血管风险事件预测及其应用

    公开(公告)号：US20150168423A1

    公开(公告)日：2015-06-18

    申请号：US14145026

    申请日：2013-12-31

    Applicant: SOMALOGIC, INC.

    Inventor： Rosalynn Dianne GILL ,  Stephen Alaric WILLIAMS ,  Alex A.E. STEWART ,  Robert MEHLER ,  Trudi FOREMAN ,  Britta SINGER

    IPC: G01N33/68

    CPC classification number: G01N33/6872 ,  G01N33/6893 ,  G01N2333/51 ,  G01N2800/32 ,  G01N2800/50 ,  G01N2800/60

    Abstract: The present disclosure includes biomarkers, methods, devices, reagents, systems, and kits for the evaluation of risk of a caradiovascular (CV) Event within 5 years. In one aspect, the disclosure provides biomarkers that can be used alone or in various combinations to evaluate risk of a CV event within 5 years. In another aspect, methods are provided for evaluating risk of a CV event within 5 years in an individual, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 1. In a further aspect, methods are provided for evaluating the risk of a CV, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 2. In a further aspect, methods are provided for evaluating the risk of a CV event in an individual, generally within 5 years, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 3.

    Abstract translation: 本公开内容包括用于在5年内评估心血管（CV）事件的风险的生物标志物，方法，装置，试剂，系统和试剂盒。 一方面，本公开提供可以单独使用或以各种组合使用以评估5年内CV事件的风险的生物标志物。 在另一方面，提供了用于在个体中评估5年内的CV事件的风险的方法，其中所述方法包括在来自个体的生物样品中检测至少一个对应于选自组中的生物标志物的生物标记值 在另一方面，提供了用于评估CV的风险的方法，其中所述方法包括在来自个体的生物样品中检测至少一种对应于至少一种选自以下的生物标志物的生物标记值 该组生物标志物在表2中提供。在另一方面，提供了用于评估个体中CV事件的风险的方法，通常在5年内，其中所述方法包括在来自个体的生物样品中至少检测 一个生物标记值对应于选自表3中提供的生物标志物组的至少一种生物标志物。

    Cardiovascular Risk Event Prediction and Uses Thereof
    4.
    发明申请
    Cardiovascular Risk Event Prediction and Uses Thereof 审中-公开

    公开(公告)号：US20130085079A1

    公开(公告)日：2013-04-04

    申请号：US13631567

    申请日：2012-09-28

    Applicant: SOMALOGIC, INC.

    Inventor： Rosalynn Dianne GILL ,  Stephen Alaric WILLIAMS ,  Alex A.E. STEWART ,  Robert MEHLER ,  Trudi FOREMAN ,  Britta SINGER

    IPC: C40B30/04 ,  C40B40/06 ,  C40B40/10

    CPC classification number: G01N33/6872 ,  G01N33/6893 ,  G01N2333/51 ,  G01N2800/32 ,  G01N2800/50 ,  G01N2800/60

    Abstract: The present disclosure includes biomarkers, methods, devices, reagents, systems, and kits for the evaluation of risk of a caradiovascular (CV) Event within 5 years. In one aspect, the disclosure provides biomarkers that can be used alone or in various combinations to evaluate risk of a CV event within 5 years. In another aspect, methods are provided for evaluating risk of a CV event within 5 years in an individual, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 1. In a further aspect, methods are provided for evaluating the risk of a CV, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 2. In a further aspect, methods are provided for evaluating the risk of a CV event in an individual, generally within 5 years, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 3.

    Lung Cancer Biomarkers and Uses Thereof
    5.
    发明申请
    Lung Cancer Biomarkers and Uses Thereof 有权

    公开(公告)号：US20220065872A1

    公开(公告)日：2022-03-03

    申请号：US17480698

    申请日：2021-09-21

    Applicant: SomaLogic, Inc.

    Inventor： Michael RIEL-MEHAN ,  Alex A. E. STEWART ,  Rachel M. OSTROFF ,  Stephen Alaric WILLIAMS ,  Edward N. Brody

    IPC: G01N33/68 ,  G16B20/00 ,  G16B99/00 ,  C12Q1/6886 ,  G01N33/574 ,  G16B20/20 ,  G16B25/10 ,  G16B40/30

    Abstract: The present application includes biomarkers, methods, devices, reagents, systems, and kits for the detection and diagnosis of non-small cell lung cancer and general cancer. In one aspect, the application provides biomarkers that can be used alone or in various combinations to diagnose non-small cell lung cancer or general cancer. In another aspect, methods are provided for diagnosing non-small cell lung cancer in an individual, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 1, wherein the individual is classified as having lung cancer, or the likelihood of the individual having lung cancer is determined, based on the at least one biomarker value. In another aspect, methods are provided for diagnosing cancer in an individual, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 19, wherein the individual is classified as having cancer, or the likelihood of the individual having cancer is determined, based on the at least one biomarker value.

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