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公开(公告)号：US20240226453A9
公开(公告)日：2024-07-11
申请号：US18534306
申请日：2023-12-08
Applicant: Sanofi
Inventor： Michael Jugl , Stefan Blancke , Axel Teucher , Ralph Donald Quentin Collings , James Robert Coop , James Anthony West , Stephen Francis Gilmore , Daniel David Higgins , Mark Digby Teucher , Anthony Paul Morris , Matthew Meredith Jones , William Geoffrey Arthur Marsh , Samuel Keir Steel
IPC: A61M5/315
CPC classification number: A61M5/31585 , A61M5/31526 , A61M5/31553 , A61M2005/3143
Abstract: A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.
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公开(公告)号：US11865318B2
公开(公告)日：2024-01-09
申请号：US16976963
申请日：2019-02-27
Applicant: SANOFI
Inventor： Michael Jugl , Stefan Blancke
CPC classification number: A61M5/31585 , A61M5/31515 , A61M5/31526 , A61M5/31595 , A61M2005/2477 , A61M2005/31516
Abstract: The present disclosure relates to an injection device configured to expel a dose of a medicament, the injection device comprising: an elongated housing extending in a longitudinal direction, a piston rod movable relative to the housing in a longitudinal distal direction to exert a dispensing pressure onto a bung of a cartridge at least partially filled with an injectable medicament, a rod extension movably arranged on or in a distal end of the piston rod, a driver operably engaged with the piston rod and movable relative to the housing in a longitudinal proximal direction for setting of the dose and movable relative to the housing in the longitudinal distal direction for dispensing of the dose, and an adjuster arranged on or in the driver and operably engaged with the rod extension to move the rod extension in longitudinal direction relative to the piston rod.
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公开(公告)号：US20230293822A1
公开(公告)日：2023-09-21
申请号：US17928107
申请日：2021-06-08
Applicant: Sanofi
Inventor： Michael Jugl , Stefan Blancke
IPC: A61M5/315
CPC classification number: A61M5/31551 , A61M2205/50 , A61M2205/587
Abstract: The present disclosure refers to a drug delivery device including, a dose setting and/or drive mechanism including a stationary housing having at least one internal groove on an inner surface; a driver positioned within the housing which is moveable relative to the housing during dose dialing and which is moveable relative to the housing during dose dispensing; and at least one flexible tab that is biased to engage the at least one internal groove such that the at least one flexible tab repeatedly engages and disengages the at least one internal groove during dose dialing or during dose dispensing, thereby performing an oscillating movement between two positions including a first position in which the at least one flexible tab engages the at least one internal groove and a second position in which the at least one flexible tab is disengaged from the at least one internal groove.
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公开(公告)号：US20230067401A1
公开(公告)日：2023-03-02
申请号：US17958817
申请日：2022-10-03
Applicant: Sanofi
Inventor： Axel Teucher , Michael Jugl , Stefan Blancke
Abstract: An injection device for setting and injecting of a dose of a medicament includes: an acoustic feedback arrangement comprising: a first feedback element having a first engaging section and having a free end section located at a predetermined distance from the first engaging section, a second feedback element having a second engaging section configured to engage with the first engaging section, wherein the first feedback element is movable, pivotable or resiliently deformable along a first direction (d1) relative to the second feedback element from an initial state (i) towards a biased state (b), and a sound generator formed by the first engaging section or audibly engageable with the free end section of the first feedback element.
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公开(公告)号：US11497854B2
公开(公告)日：2022-11-15
申请号：US16766204
申请日：2018-11-27
Applicant: SANOFI
Inventor： Ralph Donald Quentin Collings , James Robert Coop , James Anthony West , Stephen Francis Gilmore , Daniel David Higgins , Mark Digby Teucher , Stefan Blancke
IPC: A61M5/315
Abstract: A system comprises a first member, a second member, and a third member, wherein the first and second members are rotatable relative to the third member, wherein the first and second members are coupled to one another by a dead-angle follower coupling, wherein the dead-angle follower coupling is configured such that the first and second members are rotatable relative to one another, wherein the second and third members are rotationally coupled to one another by a switchable coupling mechanism, wherein the switchable coupling mechanism is switchable between two different states, a locked state and a non-locked state, wherein the maximum torque transferable between the second and third members via the switchable coupling mechanism in the locked state is greater than in the non-locked state, wherein the switchable coupling mechanism is in the locked state when the first member is in a locking position relative to the second member.
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Patent Agency Ranking
公开(公告)号：US11484662B2
公开(公告)日：2022-11-01
申请号：US15778263
申请日：2016-11-21
Applicant: Sanofi-Aventis Deutschland GMBH
Inventor： Michael Jugl , Axel Teucher , Stefan Blancke , Michael Helmer , Marc Schader , Sebastian Braun
Abstract: A medicament delivery device comprising: a main body arranged to receive a medicament cartridge sealed with a penetrable barrier; a needle carrier carrying a needle; a cap removably coupled to the needle carrier, a pre-stressed spring connected to the needle carrier and to the main body, wherein the pre-stressed spring is held by an activation element coupled to the cap, wherein the activation element is arranged to release the spring when the cap is pulled in a distal direction from the device, thereby causing the needle carrier to move axially in a proximal direction.
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公开(公告)号：US20220226580A1
公开(公告)日：2022-07-21
申请号：US17617099
申请日：2020-06-12
Applicant: Sanofi
Inventor： Michael Jugl , Stefan Blancke , Axel Teucher , Jörg Bigalke , Maurice Toporek
Abstract: A drug delivery device comprising a first module comprising a zinc-air cell located at one end of the first module, a second module for attachment to the one end of the first module and comprising electronics, and activation means for activating the zinc-air cell and being designed such that at least one air hole is created in an air tight sealing of the zinc-air cell when the second module is attached to the one end of the first module.
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公开(公告)号：US11065389B2
公开(公告)日：2021-07-20
申请号：US16373420
申请日：2019-04-02
Applicant: Sanofi-Aventis Deutschland GMBH
Inventor： Stefan Blancke , Axel Teucher , Michael Jugl , Christiane Schneider
Abstract: An assembly for a drug delivery device is presented. The assembly comprises a housing and a piston rod having a longitudinal axis, a distal end and a proximal end. The piston rod further comprises a piston rod interaction feature, and a piston rod guide being movable with respect to the piston rod, the piston rod guide further comprising a guide interaction feature corresponding to the piston rod interaction feature, the piston rod guide being movable with respect to the piston rod to switch between a first state and a second state of the assembly, the second state being different from the first state. The assembly is configured such that, in a first state of the assembly, the piston rod guide is in a first axial position relative to the piston rod in which the piston rod interaction feature is arranged to interact with the guide interaction feature to prevent proximal movement of the piston rod with respect to the housing, and wherein, in a second state of the assembly being different from the first state, the piston rod guide is in a second axial position relative to the piston rod, the second axial position being different from the first axial position, wherein, in the second axial position, the piston rod interaction feature and the guide interaction feature are arranged such that proximal movement of the piston rod with respect to the housing is allowed.
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公开(公告)号：US10537684B2
公开(公告)日：2020-01-21
申请号：US15037339
申请日：2014-11-17
Applicant: Sanofi-Aventis Deutschland GmbH
Inventor： Stefan Blancke , Axel Teucher , Michael Jugl , Christiane Schneider
Abstract: An assembly for a drug delivery device is presented. The assembly comprises a housing and a piston rod having a longitudinal axis, a distal end and a proximal end. The piston rod further comprises a piston rod interaction feature, and a piston rod guide being movable with respect to the piston rod, the piston rod guide further comprising a guide interaction feature corresponding to the piston rod interaction feature, the piston rod guide being movable with respect to the piston rod to switch between a first state and a second state of the assembly, the second state being different from the first state. The assembly is configured such that, in a first state of the assembly, the piston rod guide is in a first axial position relative to the piston rod in which the piston rod interaction feature is arranged to interact with the guide interaction feature to prevent proximal movement of the piston rod with respect to the housing, and wherein, in a second state of the assembly being different from the first state, the piston rod guide is in a second axial position relative to the piston rod, the second axial position being different from the first axial position, wherein, in the second axial position, the piston rod interaction feature and the guide interaction feature are arranged such that proximal movement of the piston rod with respect to the housing is allowed.
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公开(公告)号：US20180339111A1
公开(公告)日：2018-11-29
申请号：US15778263
申请日：2016-11-21
Applicant: Sanofi-Aventis Deutschland GMBH
Inventor： Michael Jugl , Axel Teucher , Stefan Blancke , Michael Helmer , Marc Schader , Sebastian Braun
Abstract: A medicament delivery device comprising: a main body arranged to receive a medicament cartridge sealed with a penetrable barrier; a needle carrier carrying a needle; a cap removably coupled to the needle carrier, a pre-stressed spring connected to the needle carrier and to the main body, wherein the pre-stressed spring is held by an activation element coupled to the cap, wherein the activation element is arranged to release the spring when the cap is pulled in a distal direction from the device, thereby causing the needle carrier to move axially in a proximal direction.
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