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1.发明授权Apparatus for delivery of device and antimicrobial agent into trans-dermal catheter 有权用于将装置和抗微生物剂递送到透皮导管中的装置公开(公告)号：US09022984B2
公开(公告)日：2015-05-05
申请号：US12605963
申请日：2009-10-26
CPC分类号： A61M25/01 , A61L2/186 , A61L2202/24 , A61M5/001 , A61M25/0017 , A61M25/0105 , A61M25/0111 , A61M39/165 , A61M39/18 , A61M39/20 , A61M2025/0018 , A61M2025/0019 , A61M2025/0056 , A61M2209/10
摘要： An apparatus for delivery of an elongate member into the lumen of a trans-dermal catheter. In a preferred embodiment, the apparatus comprises a protective sheath configured to at least substantially surround an elongate member; and slidable member configured to travel along the protective sheath, the slidable member operatively coupled to the elongate member; wherein the elongate member is insertable into a lumen of a trans-dermal catheter by moving the slidable member along at least a part of the length of the protective sheath. In another embodiment, the apparatus comprises a protective sheath configured to at least substantially surround an elongate member; a slidable member configured to travel along the protective sheath, the slidable member operatively coupled to the elongate member; and a connecting member positioned on the distal end of the protective sheath, the connecting member configured to lock onto the distal end of a trans-dermal catheter; wherein the elongate member is insertable into the lumen of the trans-dermal catheter by moving the slidable member along at least a part of the length of the protective sheath.
摘要翻译： 用于将细长构件递送到经皮导管的内腔中的装置。 在优选实施例中，该装置包括被配置为至少基本上围绕细长构件的保护护套; 以及可滑动构件，其构造成沿着所述保护护套行进，所述可滑动构件可操作地联接到所述细长构件; 其中所述细长构件通过沿着所述保护护套的长度的至少一部分移动所述可滑动构件而可插入到经皮导管的内腔中。 在另一个实施例中，该装置包括被配置为至少基本上围绕细长构件的保护套; 可滑动构件，其构造成沿着所述保护护套行进，所述可滑动构件可操作地联接到所述细长构件; 以及连接构件，所述连接构件定位在所述保护护套的远端上，所述连接构件构造成锁定在经皮导管的远端上; 其中所述细长构件通过沿着所述保护护套的长度的至少一部分移动所述可滑动构件而可插入所述经皮导管的内腔中。
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2.发明申请APPARATUS FOR DELIVERY OF DEVICE AND ANTIMICROBIAL AGENT INTO TRANS-DERMAL CATHETER 有权用于将装置和抗微生物剂递送到透明导管的装置公开(公告)号：US20100106102A1
公开(公告)日：2010-04-29
申请号：US12605963
申请日：2009-10-26
IPC分类号： A61L29/14
CPC分类号： A61M25/01 , A61L2/186 , A61L2202/24 , A61M5/001 , A61M25/0017 , A61M25/0105 , A61M25/0111 , A61M39/165 , A61M39/18 , A61M39/20 , A61M2025/0018 , A61M2025/0019 , A61M2025/0056 , A61M2209/10
摘要： An apparatus for delivery of an elongate member into the lumen of a trans-dermal catheter. In a preferred embodiment, the apparatus comprises a protective sheath configured to at least substantially surround an elongate member; and slidable member configured to travel along the protective sheath, the slidable member operatively coupled to the elongate member; wherein the elongate member is insertable into a lumen of a trans-dermal catheter by moving the slidable member along at least a part of the length of the protective sheath. In another embodiment, the apparatus comprises a protective sheath configured to at least substantially surround an elongate member; a slidable member configured to travel along the protective sheath, the slidable member operatively coupled to the elongate member; and a connecting member positioned on the distal end of the protective sheath, the connecting member configured to lock onto the distal end of a trans-dermal catheter; wherein the elongate member is insertable into the lumen of the trans-dermal catheter by moving the slidable member along at least a part of the length of the protective sheath.
摘要翻译： 用于将细长构件递送到经皮导管的内腔中的装置。 在优选实施例中，该装置包括被配置为至少基本上围绕细长构件的保护护套; 以及可滑动构件，其构造成沿着所述保护护套行进，所述可滑动构件可操作地联接到所述细长构件; 其中所述细长构件通过沿着所述保护护套的长度的至少一部分移动所述可滑动构件而可插入到经皮导管的内腔中。 在另一个实施例中，该装置包括被配置为至少基本上围绕细长构件的保护套; 可滑动构件，其构造成沿着所述保护护套行进，所述可滑动构件可操作地联接到所述细长构件; 以及连接构件，所述连接构件定位在所述保护护套的远端上，所述连接构件构造成锁定在经皮导管的远端上; 其中所述细长构件通过沿着所述保护护套的长度的至少一部分移动所述可滑动构件而可插入所述经皮导管的内腔中。
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公开(公告)号：US20100106103A1
公开(公告)日：2010-04-29
申请号：US12605966
申请日：2009-10-26
申请人： Robert J. Ziebol , William S. Nettekoven , Gregory G. Carlson , Robert G. Walsh , Robert H. Weinmann
发明人： Robert J. Ziebol , William S. Nettekoven , Gregory G. Carlson , Robert G. Walsh , Robert H. Weinmann
IPC分类号： A61L15/44
CPC分类号： A61M25/01 , A61L2/186 , A61L2202/24 , A61M5/001 , A61M25/0017 , A61M25/0105 , A61M25/0111 , A61M39/165 , A61M39/18 , A61M39/20 , A61M2025/0018 , A61M2025/0019 , A61M2025/0056 , A61M2209/10
摘要： A system for delivering an antimicrobial agent into the lumen of a trans-dermal catheter. In an embodiment, the system comprises an elongate member configured for insertion into a lumen of a catheter; an expandable portion of the elongate member, said expandable portion configured to increase in diameter upon exposure to an aqueous fluid; and an antimicrobial composition positioned to be delivered into the catheter. In another embodiment, the system comprises an elongate member configured for insertion into a lumen of a trans-dermal catheter, said elongate member comprising a hydrogel; and an antimicrobial composition positioned to be delivered into the catheter; wherein the elongate member defines a volume of liquid that is at least substantially contained within the lumen of the trans-dermal catheter.
摘要翻译： 用于将抗微生物剂递送到经皮导管的内腔中的系统。 在一个实施例中，系统包括构造成用于插入导管的内腔中的细长构件; 所述细长构件的可膨胀部分，所述可膨胀部分构造成在暴露于含水流体时直径增加; 以及定位成被输送到导管中的抗微生物组合物。 在另一个实施例中，该系统包括构造成用于插入经皮导管内腔的细长构件，所述细长构件包括水凝胶; 以及定位成被输送到导管中的抗微生物组合物; 其中所述细长构件限定至少基本上包含在所述经皮导管的内腔内的一定体积的液体。
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公开(公告)号：US09072868B2
公开(公告)日：2015-07-07
申请号：US12605966
申请日：2009-10-26
申请人： Robert J. Ziebol , William S. Nettekoven , Gregory G. Carlson , Robert G. Walsh , Robert H. Weinmann
发明人： Robert J. Ziebol , William S. Nettekoven , Gregory G. Carlson , Robert G. Walsh , Robert H. Weinmann
CPC分类号： A61M25/01 , A61L2/186 , A61L2202/24 , A61M5/001 , A61M25/0017 , A61M25/0105 , A61M25/0111 , A61M39/165 , A61M39/18 , A61M39/20 , A61M2025/0018 , A61M2025/0019 , A61M2025/0056 , A61M2209/10
摘要： A system for delivering an antimicrobial agent into the lumen of a trans-dermal catheter. In an embodiment, the system comprises an elongate member configured for insertion into a lumen of a catheter; an expandable portion of the elongate member, said expandable portion configured to increase in diameter upon exposure to an aqueous fluid; and an antimicrobial composition positioned to be delivered into the catheter. In another embodiment, the system comprises an elongate member configured for insertion into a lumen of a trans-dermal catheter, said elongate member comprising a hydrogel; and an antimicrobial composition positioned to be delivered into the catheter; wherein the elongate member defines a volume of liquid that is at least substantially contained within the lumen of the trans-dermal catheter.
摘要翻译： 用于将抗微生物剂递送到经皮导管的内腔中的系统。 在一个实施例中，系统包括构造成用于插入导管的内腔中的细长构件; 所述细长构件的可膨胀部分，所述可膨胀部分构造成在暴露于含水流体时直径增加; 以及定位成被输送到导管中的抗微生物组合物。 在另一个实施例中，该系统包括构造成用于插入经皮导管内腔的细长构件，所述细长构件包括水凝胶; 以及定位成被输送到导管中的抗微生物组合物; 其中所述细长构件限定至少基本上包含在所述经皮导管的内腔内的一定体积的液体。
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公开(公告)号：US5833682A
公开(公告)日：1998-11-10
申请号：US697530
申请日：1996-08-26
申请人： Curtis A. Amplatz , Mark A. Rydell , Robert J. Ziebol , Christopher H. Porter , Michael Kasinkas
发明人： Curtis A. Amplatz , Mark A. Rydell , Robert J. Ziebol , Christopher H. Porter , Michael Kasinkas
CPC分类号： A61B18/24 , A61B2017/22051 , A61B2018/2261 , A61M25/104
摘要： A light delivery system for use in irradiating vascular tissue includes a balloon catheter with a working lumen for receiving an optical fiber therein and an inflation/flushing lumen adapted to receive a liquid at a proximal end and leading to a space defined within the balloon member attached to a distal end of the catheter. The balloon member has a pattern of holes or pores in the wall thereof through which the saline may flow when the balloon is inflated, causing any blood or other absorbing substances that may interfere with good radiant energy transmission to be flushed away from the treatment site.
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公开(公告)号：US5964751A
公开(公告)日：1999-10-12
申请号：US140116
申请日：1998-08-25
申请人： Curtis A. Amplatz , Mark A. Rydell , Robert J. Ziebol , Christopher H. Porter , Michael Kasinkas
发明人： Curtis A. Amplatz , Mark A. Rydell , Robert J. Ziebol , Christopher H. Porter , Michael Kasinkas
CPC分类号： A61B17/22 , A61B18/22 , A61B2017/22051 , A61B2018/2261 , A61M1/00 , A61M25/104 , A61M29/02
摘要： A light delivery system for use in irradiating vascular tissue includes a balloon catheter with a working lumen for receiving an optical fiber therein and an inflation/flushing lumen adapted to receive a liquid at a proximal end and leading to a space defined within the balloon member attached to a distal end of the catheter. The balloon member has a pattern of holes or pores in the wall thereof through which the saline may flow when the balloon is inflated, causing any blood or other absorbing substances that may interfere with good radiant energy transmission to be flushed away from the treatment site.
摘要翻译： 用于照射血管组织的光输送系统包括球囊导管，其具有用于在其中接收光纤的工作腔，以及适于在近端接收液体并且导致限定在所述球囊构件附近的空间的充气/冲洗腔 到导管的远端。 气球构件在其壁中具有孔或孔的图案，当气囊膨胀时，盐可以通过该孔或孔流动，导致可能干扰良好的辐射能量传递的任何血液或其它吸收物质从治疗部位冲洗掉。
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公开(公告)号：US5239604A
公开(公告)日：1993-08-24
申请号：US963419
申请日：1992-10-19
IPC分类号： G02B6/38
CPC分类号： G02B6/3855 , G02B6/3835 , G02B6/3838 , G02B6/3857 , G02B6/3846 , G02B6/3854
摘要： In an optical fiber connector subassembly, a ferrule is received within a hollow cylindrical crimp. The ferrule has a bore extending through the ferrule with a longitudinal slot formed within the ferrule exposing a portion of the bore. The crimp is provided with first and second crimping portions. The first crimping portion extends into the slot and opposes the ferrule bore. The second crimping portion is diametrically opposed to the first crimping portion and opposes an exterior surface of the ferrule. Application of a force to the sides of the crimp causes the first and second crimping portions to be spaced apart a distance sufficient to insert a fiber within the ferrule bore. Release of the force causes the first and second crimping portions to be biased toward one another to securely crimp the fiber within the ferrule.
摘要翻译： 在光纤连接器子组件中，套圈被容纳在中空圆柱形卷边内。 套管具有延伸穿过套圈的孔，其中形成在套圈内的纵向槽暴露孔的一部分。 卷曲设置有第一和第二压接部。 第一压接部分延伸到槽中并与套圈孔相对。 第二压接部分与第一压接部分直径相对并与套圈的外表面相对。 将力施加到卷曲的侧面使得第一和第二压接部分间隔开足以将纤维插入套圈孔内的距离。 力的释放使得第一和第二压接部彼此偏压以将纤维牢固地卷曲在套圈内。
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公开(公告)号：US5159655A
公开(公告)日：1992-10-27
申请号：US648491
申请日：1991-01-31
IPC分类号： G02B6/38
CPC分类号： G02B6/3801 , G02B6/3835 , G02B6/3838 , G02B6/3846 , G02B6/3855 , G02B6/3857 , G02B6/3854
摘要： In an optical fiber connector subassembly, a ferrule is received within a hollow cylindrical crimp. The ferrule has a bore extending through the ferrule with a longitudinal slot formed within the ferrule exposing a portion of the bore. The crimp is provided with first and second crimping portions. The first crimping portion extends into the slot and opposes the ferrule bore. The second crimping portion is diametrically opposed to the first crimping portion and opposes an exterior surface of the ferrule. Application of a force to the sides of the crimp causes the first and second crimping portions to be spaced apart a distance sufficient to insert a fiber within the ferrule bore. Release of the force causes the first and second crimping portions to be biased toward one another to securely crimp the fiber within the ferrule.
摘要翻译： 在光纤连接器子组件中，套圈被容纳在中空圆柱形卷边内。 套管具有延伸穿过套圈的孔，其中形成在套圈内的纵向槽暴露孔的一部分。 卷曲设置有第一和第二压接部。 第一压接部分延伸到槽中并与套圈孔相对。 第二压接部分与第一压接部分直径相对并与套圈的外表面相对。 将力施加到卷曲的侧面使得第一和第二压接部分间隔开足以将纤维插入套圈孔内的距离。 力的释放使得第一和第二压接部彼此偏压以将纤维牢固地卷曲在套圈内。
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公开(公告)号：US08690815B2
公开(公告)日：2014-04-08
申请号：US12831092
申请日：2010-07-06
CPC分类号： A61B17/11 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61F2/064 , A61M1/1006 , A61M1/1008 , A61M1/3653 , A61M1/3655 , A61M1/3659 , A61M1/3661 , A61M39/10
摘要： Vascular access systems for performing hemodialysis are disclosed. The vascular access system contemplates a catheter section adapted for insertion into a vein and a graft section adapted for attachment to an artery. The catheter section may have metal or polymer wall reinforcements that allow the use of thin-walled, small outer diameter conduits for the vascular access system. One or more of the adhered, embedded or bonded conduit reinforcement structures may be removable without significant damage to the conduit sections to facilitate attachment of the sections, or to a connector between the sections. Various self-sealing materials are provided for use in the vascular access system, as well as temporary access sites and flow control/sensor systems.
摘要翻译： 公开了用于进行血液透析的血管通路系统。 血管通路系统考虑适于插入静脉的导管部分和适于附接到动脉的移植部分。 导管部分可以具有允许使用用于血管通路系统的薄壁的小外径导管的金属或聚合物壁增强件。 粘合的，嵌入的或粘合的导管加强结构中的一个或多个可以是可移除的，而不会对管道部分造成显着的损害，以便于部分的连接或部分之间的连接器的连接。 提供各种自密封材料用于血管通路系统以及临时进入位置和流量控制/传感器系统。
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公开(公告)号：US20130144258A1
公开(公告)日：2013-06-06
申请号：US13752385
申请日：2013-01-28
申请人： Robert J. Ziebol , Keith J. Modert
发明人： Robert J. Ziebol , Keith J. Modert
IPC分类号： A61M25/00
CPC分类号： A61M25/0045 , A61L2/186 , A61L29/16 , A61L2202/24 , A61L2300/206 , A61L2300/404 , A61L2420/02 , A61M5/001 , A61M25/00 , A61M2025/0019 , A61M2209/10
摘要： Systems, methods, and articles for delivering an antimicrobial composition into the lumen of a trans-dermal catheter and to proximal elements of the transdermal catheter are disclosed. In an embodiment, the system comprises an elongate member configured for insertion into a lumen of a catheter, the elongate member containing an antimicrobial. In an alternative embodiment, an antimicrobial composition placed on an interior surface a cap element, and transfers antimicrobial to the exterior of the proximal end of the transdermal catheter.
摘要翻译： 公开了用于将抗微生物组合物递送到经皮导管的内腔和经皮导管的近端元件的系统，方法和制品。 在一个实施例中，该系统包括构造成用于插入导管的内腔中的细长构件，细长构件包含抗微生物剂。 在替代实施方案中，将抗微生物组合物置于内表面上盖帽元件，并将抗微生物剂转移至透皮导管近端的外部。
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