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1.发明申请HISTONE DEACETYLASE INHIBITORS BASED ON DERIVATIVES OF TRICYCLIC POLYHYDROACRIDINE AND ANALOGS POSSESSING FUSED SATURATED FIVE-AND-SEVEN-MEMBERED RINGS 审中-公开基于TRICYCLIC聚羟基吡啶衍生物的组蛋白脱乙酰壳多糖抑制剂和受损的饱和饱和五元配合环的模拟物公开(公告)号：US20160122340A1
公开(公告)日：2016-05-05
申请号：US14890031
申请日：2014-05-09
发明人： Fernando Pedro COSSÍO MORA , Yosu Ion VARA SALAZAR , María del Carmen MASDEU MARGALEF , María Remedios ALCALÁ CAFFARENA , Sergio VILLAFRUELA CÁNEVA , Dorleta OTAEGUI ANSA , Eneko ALDABA ARÉVALO , Aizpea ZUBIA OLASCOAGA , Eider SAN SEBASTIÁN LARZABAL
IPC分类号： C07D471/04 , C07D401/12 , C07D219/04 , C07D219/10 , C07D221/16
CPC分类号： C07D471/04 , C07D219/04 , C07D219/10 , C07D221/06 , C07D221/16 , C07D401/12
摘要： The present invention refers to compounds of formula (I): as well as to a method for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or chemoprevention of cancer hematological malignancy, proliferative diseases, neurological disorders and immunological disorders.
摘要翻译： 本发明涉及式（I）的化合物：以及其制备方法，包含其的药物组合物及其用于治疗和/或化学预防癌症血液恶性肿瘤，增殖性疾病，神经障碍和免疫学 疾病
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2.发明申请INDOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH INDOLES AND THEIR USE AS DNA METHYLATION MODULATORS 审中-公开含有这些衍生物，含有此类化学物质的药物组合物及其作为DNA甲基化调节剂的用途公开(公告)号：US20150336889A1
公开(公告)日：2015-11-26
申请号：US14441086
申请日：2013-11-07
发明人： Fernando Pedro COSSÍO MORA , Yosu Ion VARA SALAZAR , María del Carmen MASDEU MARGALEF , María Remedios ALCALÁ CAFFARENA , Sergio VILLAFRUELA CÁNEVA , Dorleta OTAEGUI ANSA , Eneko ALDABA ARÉVALO , Eider SAN SEBASTIÁN LARZABAL , Aizpea ZUBIA OLASCOAGA
IPC分类号： C07D209/12
CPC分类号： C07C225/16 , C07D209/12
摘要： The present invention refers to compounds of formula (I): as well as to a method for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or chemoprevention of cancer hematological malignancy, proliferative diseases, genetic diseases, neurological disorders and immunological disorders.
摘要翻译： 本发明涉及式（I）化合物：以及其制备方法，包含其的药物组合物及其用于治疗和/或化学预防癌症血液恶性肿瘤，增殖性疾病，遗传疾病，神经系统疾病 疾病和免疫学障碍。
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