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公开(公告)号:US09945782B2
公开(公告)日:2018-04-17
申请号:US15660961
申请日:2017-07-27
Applicant: Personal Genomics, Inc.
Inventor: Hsin-Yi Hsieh , Sheng-Fu Lin , Teng-Chien Yu
CPC classification number: G01N21/6454 , G01N21/648 , G01N2021/6471 , G01N2021/6478 , G01N2201/0642 , G02B6/0036 , G02B6/005 , G02B6/0053
Abstract: An optical sensing module is configured to detect a characteristic of a sample. The optical sensing module includes a light source, a light guide plate, a first cladding layer, a light converging layer, a filter layer, and a plurality of sensors. The light source is configured to provide an exciting beam. Positions of the sensors correspond to positions of the holes. After the exciting beam enters the light guide plate, at least one portion of the exciting beam is transmitted to the sample through a portion of the surface of the light guide plate exposed by the holes, the sample is excited by the exciting beam to emit a signal beam, and the signal beam passes through the light converging layer and the filter layer in an order and travels to the sensors. Another optical sensing module is also provided.
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公开(公告)号:US09891171B2
公开(公告)日:2018-02-13
申请号:US15220402
申请日:2016-07-27
Applicant: Personal Genomics, Inc.
Inventor: Sheng-Fu Lin
IPC: G01N21/64 , G01N21/25 , G01N33/543 , G01N33/52
CPC classification number: G01N21/645 , G01N21/253 , G01N21/6428 , G01N21/6452 , G01N21/6454 , G01N21/648 , G01N33/525 , G01N33/54373
Abstract: A sensing module including a sample loading layer, a sensing layer and an optical resonance layer locating between the sample loading layer and the sensing layer is provided. The sample loading layer includes at least a sample loading depression, and the sample loading depression exposes part of the optical resonance layer, and the sample loading depression is adapted to load sample. A surface of the optical resonance layer has optical resonance structures, and the optical resonance structures are located beside bottom of the sample loading depression or below the bottom of the sample loading depression. The sensing layer is configured to receive light and turn it into electrical signals. A sensing method is also provided.
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公开(公告)号:US20170030832A1
公开(公告)日:2017-02-02
申请号:US15220402
申请日:2016-07-27
Applicant: Personal Genomics, Inc.
Inventor: Sheng-Fu Lin
IPC: G01N21/64
CPC classification number: G01N21/645 , G01N21/253 , G01N21/6428 , G01N21/6452 , G01N21/6454 , G01N21/648 , G01N33/525 , G01N33/54373
Abstract: A sensing module including a sample loading layer, a sensing layer and an optical resonance layer locating between the sample loading layer and the sensing layer is provided. The sample loading layer includes at least a sample loading depression, and the sample loading depression exposes part of the optical resonance layer, and the sample loading depression is adapted to load sample. A surface of the optical resonance layer has optical resonance structures, and the optical resonance structures are located beside bottom of the sample loading depression or below the bottom of the sample loading depression. The sensing layer is configured to receive light and turn it into electrical signals. A sensing method is also provided.
Abstract translation: 提供了一种感测模块,其包括样品加载层,感测层和定位在样品加载层和感测层之间的光学共振层。 样品加载层至少包括样品加载凹陷,并且样品加载凹陷暴露部分光学共振层,并且样品加载凹陷适于加载样品。 光学共振层的表面具有光学共振结构,并且光学共振结构位于样品负载凹陷的底部旁边或低于样品负载凹陷的底部。 感测层被配置为接收光并将其转换成电信号。 还提供了感测方法。
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公开(公告)号:US10566476B2
公开(公告)日:2020-02-18
申请号:US15713012
申请日:2017-09-22
Applicant: Personal Genomics, Inc.
Inventor: Teng-Chien Yu , Sheng-Fu Lin , Ming-Sheng Yang
Abstract: Some embodiments of the present disclosure provide an optical sensor. The optical sensor includes a semiconductive substrate; a light sensing region on the semiconductive substrate; a waveguide region configured to guide light from a wave insert portion through a waveguide portion and to a sample holding portion; and an interconnect region below the waveguide region, and the interconnect region being disposed above the light sensing region. The waveguide portion includes a first dielectric layer comprising a first refractive index and at least one second dielectric layer comprising a second refractive index, wherein the second refractive index is smaller than the first refractive index.
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公开(公告)号:US20170322157A1
公开(公告)日:2017-11-09
申请号:US15660961
申请日:2017-07-27
Applicant: Personal Genomics, Inc.
Inventor: Hsin-Yi Hsieh , Sheng-Fu Lin , Teng-Chien Yu
CPC classification number: G01N21/6454 , G01N21/648 , G01N2021/6471 , G01N2021/6478 , G01N2201/0642 , G02B6/0036 , G02B6/005 , G02B6/0053
Abstract: An optical sensing module is configured to detect a characteristic of a sample. The optical sensing module includes a light source, a light guide plate, a first cladding layer, a light converging layer, a filter layer, and a plurality of sensors. The light source is configured to provide an exciting beam. Positions of the sensors correspond to positions of the holes. After the exciting beam enters the light guide plate, at least one portion of the exciting beam is transmitted to the sample through a portion of the surface of the light guide plate exposed by the holes, the sample is excited by the exciting beam to emit a signal beam, and the signal beam passes through the light converging layer and the filter layer in an order and travels to the sensors. Another optical sensing module is also provided.
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公开(公告)号:US09778191B2
公开(公告)日:2017-10-03
申请号:US15422474
申请日:2017-02-02
Applicant: Personal Genomics, Inc.
Inventor: Hsin-Yi Hsieh , Sheng-Fu Lin , Teng-Chien Yu
CPC classification number: G01N21/6454 , G01N21/648 , G01N2021/6471 , G01N2021/6478 , G01N2201/0642 , G02B6/0036 , G02B6/005 , G02B6/0053
Abstract: An optical sensing module is configured to detect a characteristic of a sample. The optical sensing module includes a light source, a light guide plate, a first cladding layer, a light converging layer, a filter layer, and a plurality of sensors. The light source is configured to provide an exciting beam. Positions of the sensors correspond to positions of the holes. After the exciting beam enters the light guide plate, at least one portion of the exciting beam is transmitted to the sample through a portion of the surface of the light guide plate exposed by the holes, the sample is excited by the exciting beam to emit a signal beam, and the signal beam passes through the light converging layer and the filter layer in an order and travels to the sensors. Another optical sensing module is also provided.
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公开(公告)号:US09812597B2
公开(公告)日:2017-11-07
申请号:US14823815
申请日:2015-08-11
Applicant: Personal Genomics, Inc.
Inventor: Teng-Chien Yu , Sheng-Fu Lin , Ming-Sheng Yang
IPC: H01L31/0232 , B82Y20/00 , G01N21/64 , G01N21/77 , G02B6/122
CPC classification number: H01L31/02327 , B82Y20/00 , G01N21/6454 , G01N21/648 , G01N21/7703 , G02B6/1226
Abstract: Some embodiments of the present disclosure provide an optical sensor. The optical sensor includes a semiconductive substrate. A light sensing region is on the semiconductive substrate. A waveguide region is configured to guide light from a wave insert portion through a waveguide portion and to a sample holding portion. The waveguide portion includes a first dielectric layer including a first refractive index. A second dielectric layer includes a second refractive index. The second refractive index is smaller than the first refractive index. A first interconnect portion is positioned in the waveguide portion, configured to transmit electrical signal from the light sensing region to an external circuit. The sample holding portion is over the light sensing region.
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