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    METHODS, DEVICES AND SYSTEMS FOR DISTINGUISHING OVER-SENSED R-R INTERVALS FROM TRUE R-R INTERVALS
    1.
    发明公开
    METHODS, DEVICES AND SYSTEMS FOR DISTINGUISHING OVER-SENSED R-R INTERVALS FROM TRUE R-R INTERVALS 审中-公开

    公开(公告)号：US20240341662A1

    公开(公告)日：2024-10-17

    申请号：US18745627

    申请日：2024-06-17

    申请人： Pacesetter, Inc.

    发明人： Nima Badie ,  Fujian Qu ,  Jong Gill

    IPC分类号： A61B5/352 ,  A61B5/00 ,  A61B5/0245

    CPC分类号： A61B5/352 ,  A61B5/0245 ,  A61B5/686

    摘要： Described herein are methods, devices, and systems that monitor heart rate and/or for arrhythmic episodes based on sensed intervals that can include true R-R intervals as well as over-sensed R-R intervals. True R-R intervals are initially identified from an ordered list of the sensed intervals by comparing individual sensed intervals to a sum of an immediately preceding two intervals, and/or an immediately following two intervals. True R-R intervals are also identified by comparing sensed intervals to a mean or median of durations of sensed intervals already identified as true R-R intervals. Individual intervals in a remaining ordered list of sensed intervals (from which true R-R intervals have been removed) are classified as either a short interval or a long interval, and over-sensed R-R intervals are identified based on the results thereof. Such embodiments can be used, e.g., to reduce the reporting of and/or inappropriate responses to false positive tachycardia detections.

    R-R interval pattern recognition for use in arrhythmia discrimination
    3.
    发明授权
    R-R interval pattern recognition for use in arrhythmia discrimination 有权

    公开(公告)号：US11647940B2

    公开(公告)日：2023-05-16

    申请号：US17226915

    申请日：2021-04-09

    申请人： Pacesetter, Inc.

    发明人： Nima Badie ,  Fujian Qu ,  Jong Gill

    IPC分类号： A61B5/352 ,  A61B5/361 ,  A61B5/363 ,  A61N1/37 ,  A61N1/39

    CPC分类号： A61B5/352 ,  A61B5/361 ,  A61B5/363 ,  A61N1/3704 ,  A61N1/3956

    摘要： Described herein are methods, devices, and systems that improve arrhythmia episode detection specificity, such as, but not limited to, atrial fibrillation (AF) episode detection specificity. Such a method can include obtaining an ordered list of R-R intervals within a window leading up to a detection of a potential arrhythmia episode, determining a measure of a dominant repeated R-R interval pattern within the window, and comparing the measure of the dominant repeated R-R interval pattern to a pattern threshold. If the measure of the dominant repeated R-R interval pattern is below the pattern threshold, that is indicative of a regularly irregular pattern being present, and there is a determination that the detection of the potential arrhythmia episode does not correspond to an actual arrhythmia episode. Such embodiments can beneficially be used to significantly reduce the number of false positive arrhythmia detections.

    METHODS AND SYSTEMS TO MANAGE PRESENTATION OF REPRESENTATIVE CARDIAC ACTIVITY SEGMENTS FOR CLUSTERS OF SUCH SEGMENTS
    4.
    发明申请
    METHODS AND SYSTEMS TO MANAGE PRESENTATION OF REPRESENTATIVE CARDIAC ACTIVITY SEGMENTS FOR CLUSTERS OF SUCH SEGMENTS 有权

    公开(公告)号：US20220167903A1

    公开(公告)日：2022-06-02

    申请号：US17399605

    申请日：2021-08-11

    申请人： Pacesetter, Inc.

    发明人： Kevin J. Davis ,  Fujian Qu ,  Nima Badie ,  Fady Dawoud ,  Leyla Sabet

    IPC分类号： A61B5/35 ,  A61B5/00

    摘要： Methods and systems are provided for managing presentation of cardiac activity signals. The methods and systems obtain device classified (DC) data sets generated by an implantable medical device (IMD), the DC data sets including a corresponding cardiac activity (CA) segment from an episode identified by the IMD; compare the CA segments, associated with different episodes, to one another to identify a level of similarity therebetween; separate the CA segments into at least first and second clusters based on the level of similarity; designate a first representative CA segment from the first cluster to be representative of the CA segments in the first cluster; and designate a second representative CA segment from the second cluster to be representative of the CA segments in the second cluster; and a display to present the first and second representative CA segments as representative of the first and second clusters.

    METHODS AND SYSTEMS FOR DISTINGUISHING OVER-SENSED R-R INTERVALS FROM TRUE R-R INTERVALS
    5.
    发明申请
    METHODS AND SYSTEMS FOR DISTINGUISHING OVER-SENSED R-R INTERVALS FROM TRUE R-R INTERVALS 有权

    公开(公告)号：US20210236041A1

    公开(公告)日：2021-08-05

    申请号：US17153036

    申请日：2021-01-20

    申请人： Pacesetter, Inc.

    发明人： Nima Badie ,  Fujian Qu ,  Jong Gill

    IPC分类号： A61B5/352 ,  A61B5/00 ,  A61B5/0245

    摘要： Described herein are methods, devices, and systems that monitor heart rate and/or for arrhythmic episodes based on sensed intervals that can include true R-R intervals as well as over-sensed R-R intervals. True R-R intervals are initially identified from an ordered list of the sensed intervals by comparing individual sensed intervals to a sum of an immediately preceding two intervals, and/or an immediately following two intervals. True R-R intervals are also identified by comparing sensed intervals to a mean or median of durations of sensed intervals already identified as true R-R intervals. Individual intervals in a remaining ordered list of sensed intervals (from which true R-R intervals have been removed) are classified as either a short interval or a long interval, and over-sensed R-R intervals are identified based on the results thereof. Such embodiments can be used, e.g., to reduce the reporting of and/or inappropriate responses to false positive tachycardia detections.

    METHOD AND SYSTEM TO DETECT R-WAVES IN CARDIAC ARRHYTHMIC PATTERNS
    7.
    发明申请
    METHOD AND SYSTEM TO DETECT R-WAVES IN CARDIAC ARRHYTHMIC PATTERNS 审中-公开

    公开(公告)号：US20190336026A1

    公开(公告)日：2019-11-07

    申请号：US15973351

    申请日：2018-05-07

    申请人： PACESETTER, INC.

    发明人： Fady Dawoud ,  Fujian Qu ,  Stuart Rosenberg ,  Gene A. Bornzin ,  Jong Gill ,  Neha Malhotra ,  Xiaoyi Min

    IPC分类号： A61B5/04 ,  A61B5/046 ,  A61B5/0456 ,  A61B5/0464 ,  A61B5/042 ,  A61B5/00 ,  A61B5/0472

    摘要： Computer implemented methods and systems for detecting arrhythmias in cardiac activity are provided. The method is under control of one or more processors configured with specific executable instructions. The method obtains a far field cardiac activity (CA) data set that includes far field CA signals for beats. The method applies a feature enhancement function to the CA signals to form an enhanced feature in the CA data set. The method calculates an adaptive sensitivity level and sensitivity limit based on the enhanced feature from one or more beats within the CA data set and automatically iteratively analyzes a beat segment of interest by comparing the beat segment of interest to the current sensitivity level to determine whether one or more R-waves are present within the beat segment of interest. The method repeats the iterative analyzing operation while progressively adjusting the current sensitivity level until i) the one or more R-waves are detected in the beat segment of interest and/or ii) the current sensitivity level reaches the sensitivity limit. The method detects an arrhythmia within the beat segment of interest based on a presence or absence of the one or more R-waves and records results of the detecting of the arrhythmia.

    Method And System For Second Pass Confirmation Of Detected Cardiac Arrhythmic Patterns
    8.
    发明申请
    Method And System For Second Pass Confirmation Of Detected Cardiac Arrhythmic Patterns 审中-公开

    公开(公告)号：US20190336025A1

    公开(公告)日：2019-11-07

    申请号：US15973126

    申请日：2018-05-07

    申请人： PACESETTER, INC.

    发明人： Fujian Qu ,  Jong Gill ,  Neha Malhotra ,  Stuart Rosenberg ,  Gene A. Bornzin ,  Fady Dawoud

    IPC分类号： A61B5/04 ,  A61B5/046 ,  A61B5/0456 ,  A61B5/042

    摘要： A computer implemented method and system for confirming a device documented arrhythmia in cardiac activity are provided. The method is under control of one or more processors configured with executable instructions. The method obtains a cardiac activity (CA) data set that includes CA signals for a series of cardiac events and includes device documented (DD) markers within the series of cardiac events. The device documented markers are indicative of atrial fibrillation (AF) detected by the ICM utilizing an on-board R-R interval irregularity (ORI) process to analyze the CA signals. The method applies a feature enhancement function to the CA signals to form modified CA signals with enhanced sinus features and analyzes the enhanced sinus features in the modified CA signals. The method utilized a confirmatory feature detection process to identify false AF detection by the ORI process. The method records a result of the analysis identifying false AF detection by the ORI process.

    SYSTEM AND METHOD FOR DETERMINING A STIMULATION THRESHOLD FOR CLOSED LOOP SPINAL CORD STIMULATION
    9.
    发明申请
    SYSTEM AND METHOD FOR DETERMINING A STIMULATION THRESHOLD FOR CLOSED LOOP SPINAL CORD STIMULATION 审中-公开

    公开(公告)号：US20180126169A1

    公开(公告)日：2018-05-10

    申请号：US15345163

    申请日：2016-11-07

    申请人： PACESETTER, INC.

    发明人： Wenbo Hou ,  Fujian Qu ,  Stuart Rosenberg ,  Kyungmoo Ryu

    IPC分类号： A61N1/36 ,  A61N1/05 ,  A61N1/372

    CPC分类号： A61N1/36139 ,  A61N1/0551 ,  A61N1/36071 ,  A61N1/37247 ,  A61N1/37264

    摘要： System and methods are provided for determining a stimulation threshold for closed loop spinal cord stimulation (SCS). The system and methods provide a lead coupled to an implantable pulse generator (IPG). The system and methods deliver SCS pulses from the IPG to the lead electrodes in accordance with an SCS therapy, and determine an evoked compound action potential (ECAP) amplitude based on an ECAP waveform resulting from the SCS therapy. The system and methods increase the SCS therapy by increasing at least one of an amplitude, a duration, and number of the SCS pulses associated with the SCS therapy. The system and methods also include iteratively repeat the delivering, determining and increasing operations until the ECAP amplitude exhibits a downward trend divergence. The system and methods define a stimulation threshold based on the ECAP amplitude at the trend divergence.