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    Implantable medical devices, and methods of use therewith, that detect MRI systems with enhanced specificity
    2.
    发明授权
    Implantable medical devices, and methods of use therewith, that detect MRI systems with enhanced specificity 有权

    公开(公告)号：US11420069B2

    公开(公告)日：2022-08-23

    申请号：US16799510

    申请日：2020-02-24

    申请人： Pacesetter, Inc.

    发明人： Xing Pei ,  Brad Lindevig ,  Stuart Rosenberg ,  Nima Badie

    IPC分类号： A61N1/37 ,  A61N1/39 ,  A61N1/05 ,  A61N1/365 ,  G01R33/00 ,  A61B5/055 ,  G01R33/28 ,  G01R33/07 ,  G01R33/09 ,  A61N1/08

    摘要： Embodiments describe herein generally pertain to implantable medical device (IMDs), and methods for use therewith, that can be used to automatically switch an IMD from its normal operational mode to an MRI safe mode, and vice versa, within increased specificity. In certain embodiments, a controller of the IMD uses a magnetic field sensor to determine whether a first magnetic field condition is detected, and uses an accelerometer to determine whether a positional condition is detected. In response to the first magnetic field condition being detected, and the positional condition being detected, the controller can use the magnetic field sensor to determine whether a second magnetic field condition is detected, which differs from the first magnetic field condition. The controller can then cause the IMD to enter the MRI safe mode based at least in part on the first and second magnetic field conditions and the positional condition being detected.

    Implantable medical device utilizing posture and heart sounds and method of using same
    3.
    发明授权
    Implantable medical device utilizing posture and heart sounds and method of using same 有权

    公开(公告)号：US11129993B2

    公开(公告)日：2021-09-28

    申请号：US16100009

    申请日：2018-08-09

    申请人： PACESETTER, INC.

    发明人： Xiaoyi Min ,  Kyungmoo Ryu ,  Thanh Tieu ,  Gene A. Bornzin ,  Stuart Rosenberg

    IPC分类号： A61N1/365 ,  A61N1/362

    摘要： A computer implemented method and system for detecting arrhythmias in cardiac activity are provided. The method is under control of one or more processors configured with specific executable instructions. The method obtains cardiac activity (CA) signals at the electrodes of an implantable medical device (IMD) in connection multiple cardiac beats and with different IMD orientations relative to gravitational force. The method obtains acceleration signatures at a sensor of the IMD that are indicative of heart sounds generated during the cardiac beats. The method obtains device location information at the IMD, with respect to the gravitational force during the cardiac beats. The method groups the acceleration signatures associated with the first and second set of cardiac beats into the corresponding one of first and second posture bins based on the device location information. The method identifies a difference between the acceleration signals in the first posture bin in connection with treating a heart condition.

    Automated optimization of his bundle pacing for cardiac resynchronization therapy
    5.
    发明授权
    Automated optimization of his bundle pacing for cardiac resynchronization therapy 有权

    公开(公告)号：US10850107B2

    公开(公告)日：2020-12-01

    申请号：US16181234

    申请日：2018-11-05

    申请人： PACESETTER, INC.

    发明人： Wenwen Li ,  Gene A. Bornzin ,  Nima Badie ,  Stuart Rosenberg ,  Luke C. McSpadden ,  Kyungmoo Ryu

    IPC分类号： A61N1/365 ,  A61N1/02 ,  A61N1/05 ,  A61N1/362 ,  A61N1/368 ,  A61N1/37

    摘要： Systems and methods of performing cardio resynchronization therapy (CRT) on a patient heart include the use of a stimulation system having at least one processor, at least one memory, a pulse generator, a stimulating electrode disposed in proximity to a His bundle of the patient heart, and a sensing electrode adapted to sense electrical activity of the left ventricle (LV) of the patient heart. CRT is provided by applying, using the pulse generator and through the stimulating electrode, a His bundle pacing (HBP) impulse having a first impulse energy. The sensing electrode is then used to measure an LV activation time in response to the HBP impulse. At least one setting of the pulse generator is modified based on the LV activation time such that a subsequent HBP impulse may be provided by the pulse generator via the stimulating electrode using a modified impulse energy.

    Subcutaneous implantation medical device with multiple parasternal-anterior electrodes
    6.
    发明授权
    Subcutaneous implantation medical device with multiple parasternal-anterior electrodes 有权

    公开(公告)号：US10765860B2

    公开(公告)日：2020-09-08

    申请号：US15973195

    申请日：2018-05-07

    申请人： PACESETTER, INC.

    发明人： Xiaoyi Min ,  Kyungmoo Ryu ,  Keith Victorine ,  Stuart Rosenberg ,  Gene A. Bornzin

    IPC分类号： A61N1/05 ,  A61N1/39

    摘要： A subcutaneous implantable medical device and method (SIMD) provided. A pulse generator (PG) is configured to be positioned subcutaneously within a lateral region of a chest of a patient. The PG has a housing that includes a PG electrode. The PG has an electronics module. An elongated lead is electrically coupled to the pulse generator. The elongated lead includes a first electrode that is configured to be positioned along a first parasternal region proximate a sternum of the patient and a second electrode that is configured to be positioned at an anterior region of the patient. The first and second electrodes are coupled to be electrically common with one another. The electronics module is configured to provide electrical shocks for antiarrhythmic therapy along at least one shocking vector between the PG electrode and the first and second electrodes.

    Method and device for controlling left univentricular pacing therapy
    7.
    发明授权
    Method and device for controlling left univentricular pacing therapy 有权

    公开(公告)号：US10758730B2

    公开(公告)日：2020-09-01

    申请号：US15672178

    申请日：2017-08-08

    申请人： PACESETTER, INC.

    发明人： Xiaoyi Min ,  Kyungmoo Ryu ,  Stuart Rosenberg ,  David Muller

    IPC分类号： A61N1/368 ,  A61N1/365 ,  A61N1/05

    摘要： Methods, devices and program products are provided for controlling a left univentricular (LUV) pacing therapy using an implantable medical device. Electrodes are configured to be located proximate to an atrial (A) site, left ventricular (LV) site and right ventricular (RV) site of the heart. A conduction different Δ is determined based on i) an atrial-ventricular conduction delay (ARRV) between the A site and the RV site, and ii) an atrial-ventricular conduction delay (ARLV) between the A site and the LV site. A correction term ε is based on intrinsic inter-ventricular conduction delay (IVCD) between the LV and RV. An LV atrial-ventricular pacing (AVLV) delay is set based on the conduction difference Δ, a pacing latency PL and the correction term ε and manages the LUV pacing therapy based on the AVLV delay, wherein the LUV pacing therapy lacks pacing in the RV.

    SINGLE-SITE IMPLANTATION METHODS FOR MEDICAL DEVICES HAVING MULTIPLE LEADS
    8.
    发明申请
    SINGLE-SITE IMPLANTATION METHODS FOR MEDICAL DEVICES HAVING MULTIPLE LEADS 审中-公开

    公开(公告)号：US20190336747A1

    公开(公告)日：2019-11-07

    申请号：US15973249

    申请日：2018-05-07

    申请人： PACESETTER, INC.

    发明人： Avi Fischer ,  Xiaoyi Min ,  Kyungmoo Ryu ,  Gene A. Bornzin ,  Keith Victorine ,  Stuart Rosenberg ,  Shubha Asopa

    IPC分类号： A61N1/05 ,  A61N1/39 ,  A61B17/34

    摘要： Methods and devices include making an incision at a single site of a patient. The single site located at an anterior of a chest or abdomen. The method also includes inserting a tunneling tool through the incision at the single site and preparing a first tunnel to a subcutaneous posterior location. A path of the first tunnel at least one of i) extends over a plurality of Intercostal gaps of the chest or ii) extends along and within one of the intercostal gaps. The method also includes positioning a first lead having an electrode within the first tunnel and preparing a second tunnel to a subcutaneous parasternal location along the chest. The method also includes positioning a second lead having an electrode within the second tunnel and positioning a pulse generator within a subcutaneous pocket and operatively coupling the first and second leads to the pulse generator.

    METHOD AND SYSTEM TO DETECT R-WAVES IN CARDIAC ARRHYTHMIC PATTERNS
    9.
    发明申请
    METHOD AND SYSTEM TO DETECT R-WAVES IN CARDIAC ARRHYTHMIC PATTERNS 审中-公开

    公开(公告)号：US20190336026A1

    公开(公告)日：2019-11-07

    申请号：US15973351

    申请日：2018-05-07

    申请人： PACESETTER, INC.

    发明人： Fady Dawoud ,  Fujian Qu ,  Stuart Rosenberg ,  Gene A. Bornzin ,  Jong Gill ,  Neha Malhotra ,  Xiaoyi Min

    IPC分类号： A61B5/04 ,  A61B5/046 ,  A61B5/0456 ,  A61B5/0464 ,  A61B5/042 ,  A61B5/00 ,  A61B5/0472

    摘要： Computer implemented methods and systems for detecting arrhythmias in cardiac activity are provided. The method is under control of one or more processors configured with specific executable instructions. The method obtains a far field cardiac activity (CA) data set that includes far field CA signals for beats. The method applies a feature enhancement function to the CA signals to form an enhanced feature in the CA data set. The method calculates an adaptive sensitivity level and sensitivity limit based on the enhanced feature from one or more beats within the CA data set and automatically iteratively analyzes a beat segment of interest by comparing the beat segment of interest to the current sensitivity level to determine whether one or more R-waves are present within the beat segment of interest. The method repeats the iterative analyzing operation while progressively adjusting the current sensitivity level until i) the one or more R-waves are detected in the beat segment of interest and/or ii) the current sensitivity level reaches the sensitivity limit. The method detects an arrhythmia within the beat segment of interest based on a presence or absence of the one or more R-waves and records results of the detecting of the arrhythmia.

    Method And System For Second Pass Confirmation Of Detected Cardiac Arrhythmic Patterns
    10.
    发明申请
    Method And System For Second Pass Confirmation Of Detected Cardiac Arrhythmic Patterns 审中-公开

    公开(公告)号：US20190336025A1

    公开(公告)日：2019-11-07

    申请号：US15973126

    申请日：2018-05-07

    申请人： PACESETTER, INC.

    发明人： Fujian Qu ,  Jong Gill ,  Neha Malhotra ,  Stuart Rosenberg ,  Gene A. Bornzin ,  Fady Dawoud

    IPC分类号： A61B5/04 ,  A61B5/046 ,  A61B5/0456 ,  A61B5/042

    摘要： A computer implemented method and system for confirming a device documented arrhythmia in cardiac activity are provided. The method is under control of one or more processors configured with executable instructions. The method obtains a cardiac activity (CA) data set that includes CA signals for a series of cardiac events and includes device documented (DD) markers within the series of cardiac events. The device documented markers are indicative of atrial fibrillation (AF) detected by the ICM utilizing an on-board R-R interval irregularity (ORI) process to analyze the CA signals. The method applies a feature enhancement function to the CA signals to form modified CA signals with enhanced sinus features and analyzes the enhanced sinus features in the modified CA signals. The method utilized a confirmatory feature detection process to identify false AF detection by the ORI process. The method records a result of the analysis identifying false AF detection by the ORI process.