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    Structure based methods for modification of PIP-72 polypeptides and PIP-72 polypeptides derived therefrom
    6.
    发明授权
    Structure based methods for modification of PIP-72 polypeptides and PIP-72 polypeptides derived therefrom 有权

    公开(公告)号：US11208440B2

    公开(公告)日：2021-12-28

    申请号：US15557384

    申请日：2016-03-03

    申请人： PIONEER HI-BRED INTERNATIONAL, INC.

    发明人： Lu Liu ,  Jarred Kenneth Oral ,  Brad Poland ,  Ute Schellenberger

    IPC分类号： C07K14/21 ,  G16B15/20 ,  A01N63/10 ,  C12N15/82

    摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity. Structure based methods for engineering insecticidal proteins of the disclosure to have modified physical properties are provided.

    Insecticidal proteins from plants and methods for their use
    10.
    发明授权
    Insecticidal proteins from plants and methods for their use 有权

    公开(公告)号：US12116588B2

    公开(公告)日：2024-10-15

    申请号：US17973124

    申请日：2022-10-25

    申请人： PIONEER HI-BRED INTERNATIONAL, INC. ,  HEXIMA LIMITED

    发明人： Lu Liu ,  Amy Lum ,  Azalea S. Ong ,  Eric Schepers ,  Ingrid Udranszky ,  Xiaohong Zhong

    IPC分类号： C12N15/82 ,  A01N63/50 ,  C07K14/415

    CPC分类号： C12N15/8286 ,  A01N63/50 ,  C07K14/415 ,  C07K2319/00

    摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.