- 专利标题： Compositions and methods comprising sequences having meganuclease activity
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申请号： US15867385申请日： 2018-01-10
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公开(公告)号： US10150956B2公开(公告)日： 2018-12-11
- 发明人: Ericka Bermudez , Andrew Mark Cigan , James J English , Saverio Carl Falco , Huirong Gao , Lu Liu , Zhan-Bin Liu , Azalea S Ong , Sergei Svitashev , Joshua K Young
- 申请人： E. I. DUPONT DE NEMOURS AND COMPANY , PIONEER HI-BRED INTERNATIONAL, INC.
- 申请人地址： US DE Wilmington US IA Johnston
- 专利权人： E I DU PONT DE NEMOURS AND COMPANY,PIONEER HI-BRED IINTERNATIONAL, INC.
- 当前专利权人： E I DU PONT DE NEMOURS AND COMPANY,PIONEER HI-BRED IINTERNATIONAL, INC.
- 当前专利权人地址： US DE Wilmington US IA Johnston
- 主分类号： C12N9/22
- IPC分类号： C12N9/22 ; C12N15/82 ; C12N9/16 ; C12N15/81
摘要：
Compositions and methods comprising polynucleotides and polypeptides having meganuclease activity are provided. Further provided are nucleic acid constructs, yeast, plants, plant cells, explants, seeds and grain having the meganuclease sequences. Various methods of employing the meganuclease sequences are provided. Such methods include, for example, methods for producing a meganuclease with increased activity at a wide range of temperatures, methods for producing a yeast, plant, plant cell, explant or seed comprising a meganuclease with increased activity.
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