公开(公告)号：US09872980B2

公开(公告)日：2018-01-23

申请号：US14687773

申请日：2015-04-15

Applicant: PACESETTER, INC.

Inventor： Lanitia Ness ,  Martin Cholette

IPC: A61N1/00 ,  A61N1/05 ,  A61N1/36 ,  A61N1/368 ,  A61N1/08

CPC classification number: A61N1/0534 ,  A61N1/0529 ,  A61N1/0531 ,  A61N1/36 ,  A61N1/3606 ,  A61N1/36082 ,  A61N1/36103 ,  A61N1/36142 ,  A61N1/36146 ,  A61N1/3686 ,  A61N2001/083

Abstract: The present disclosure provides neurostimulation systems and methods. A neurostimulation system includes at least one anode, at least one cathode, the at least one anode and the at least one cathode configured to apply electrical stimulation to a patient, and a controller electrically coupled to the at least one anode and the at least one cathode, the controller configured to determine when one of the at least one anode and the at least one cathode fails, measure, in response to the determination, a quantity indicative of a charge density of the applied electrical stimulation, compare the measured quantity to a predetermined limit, and perform at least one action when the measured quantity exceeds the predetermined limit.

公开(公告)号：US20140243920A1

公开(公告)日：2014-08-28

申请号：US13780777

申请日：2013-02-28

Applicant: PACESETTER, INC.

Inventor： Lanitia Ness ,  Martin Cholette

IPC: A61N1/36

CPC classification number: A61N1/36114 ,  A61B5/02405 ,  A61B5/0452 ,  A61B5/4842 ,  A61B5/7275 ,  A61N1/36139 ,  G06F19/00

Abstract: Stimulation of a patient's nervous system is controlled based on cardiovascular risk assessment performed by an implantable medical device. For example, an implantable medical device may monitor cardiac electrical activity to detect changes in the ST segment. Upon detection of a certain change in the ST segment, the implantable medical device controls the application of spinal cord stimulation and/or other neurostimulation to cardiac-related sections of the patient's nervous system. In some embodiments, the implantable medical device communicates with a separate neurostimulation device to control the neurostimulation. In some embodiments, the implantable medical device delivers the neurostimulation.

Abstract translation: 基于由可植入医疗装置进行的心血管风险评估来控制患者神经系统的刺激。 例如，可植入医疗设备可以监测心脏电活动以检测ST段的变化。 当检测到ST段中的某些变化时，可植入医疗装置控制对患者神经系统的心脏相关部分的脊髓刺激和/或其它神经刺激的应用。 在一些实施例中，可植入医疗装置与独立的神经刺激装置通信以控制神经刺激。 在一些实施例中，可植入医疗装置递送神经刺激。

公开(公告)号：US20160303379A1

公开(公告)日：2016-10-20

申请号：US14687773

申请日：2015-04-15

Applicant: PACESETTER, INC.

Inventor： Lanitia Ness ,  Martin Cholette

IPC: A61N1/36

CPC classification number: A61N1/0534 ,  A61N1/0529 ,  A61N1/0531 ,  A61N1/36 ,  A61N1/3606 ,  A61N1/36082 ,  A61N1/36103 ,  A61N1/36142 ,  A61N1/36146 ,  A61N1/3686 ,  A61N2001/083

Abstract: The present disclosure provides neurostimulation systems and methods. A neurostimulation system includes at least one anode, at least one cathode, the at least one anode and the at least one cathode configured to apply electrical stimulation to a patient, and a controller electrically coupled to the at least one anode and the at least one cathode, the controller configured to determine when one of the at least one anode and the at least one cathode fails, measure, in response to the determination, a quantity indicative of a charge density of the applied electrical stimulation, compare the measured quantity to a predetermined limit, and perform at least one action when the measured quantity exceeds the predetermined limit.

Abstract translation: 本公开提供神经刺激系统和方法。 神经刺激系统包括至少一个阳极，至少一个阴极，所述至少一个阳极和至少一个阴极，被配置为对患者施加电刺激，以及控制器，电耦合到所述至少一个阳极和所述至少一个阳极 阴极，所述控制器被配置为确定所述至少一个阳极和所述至少一个阴极中的一个何时出现故障，响应于所述确定测量指示所施加的电刺激的电荷密度的量，将所测量的量与 并且当所测量的量超过预定极限时执行至少一个动作。

公开(公告)号：US20140276122A1

公开(公告)日：2014-09-18

申请号：US13829711

申请日：2013-03-14

Applicant: PACESETTER, INC.

Inventor： Gary R. Dulak ,  Laurence S. Sloman ,  Stuart Rosenberg ,  Lanitia Ness ,  Yelena Nabutovsky ,  Kwangdeok Lee ,  Rupinder Bharmi ,  Gene A. Bornzin

IPC: A61B5/04 ,  A61N1/365 ,  A61B5/0402

CPC classification number: A61B5/04012 ,  A61B5/0452 ,  A61B5/4836 ,  A61N1/36585

Abstract: A method and system for differential analysis of cardiac events are provided that include monitoring cardiac signals from a heart to detect deviations indicative of at least one of ischemia and myocardial infarction (MI). The method and system also monitor physiologic surrogate signals associated with pain to detect chest pain. Additionally, the method and system include characterizing a cardiac event exhibited by the heart based on whether the cardiac event occurs in a presence of at least one of the ischemia, IM, and chest pain.

Abstract translation: 提供了用于心脏事件差分分析的方法和系统，其包括监测来自心脏的心脏信号以检测指示至少一种缺血和心肌梗塞（MI）的偏差。 该方法和系统还监测与疼痛相关的生理代谢信号以检测胸痛。 此外，所述方法和系统包括基于在存在缺血，IM和胸痛中的至少一种的情况下是否发生心脏事件来表征心脏呈现的心脏事件。

公开(公告)号：US08838241B1

公开(公告)日：2014-09-16

申请号：US13780777

申请日：2013-02-28

Applicant: Pacesetter, Inc.

Inventor： Lanitia Ness ,  Martin Cholette

IPC: A61N1/00 ,  A61N1/36

CPC classification number: A61N1/36114 ,  A61B5/02405 ,  A61B5/0452 ,  A61B5/4842 ,  A61B5/7275 ,  A61N1/36139 ,  G06F19/00

Abstract: Stimulation of a patient's nervous system is controlled based on cardiovascular risk assessment performed by an implantable medical device. For example, an implantable medical device may monitor cardiac electrical activity to detect changes in the ST segment. Upon detection of a certain change in the ST segment, the implantable medical device controls the application of spinal cord stimulation and/or other neurostimulation to cardiac-related sections of the patient's nervous system. In some embodiments, the implantable medical device communicates with a separate neurostimulation device to control the neurostimulation. In some embodiments, the implantable medical device delivers the neurostimulation.

Abstract translation: 基于由可植入医疗装置进行的心血管风险评估来控制患者神经系统的刺激。 例如，可植入医疗设备可以监测心脏电活动以检测ST段的变化。 当检测到ST段中的某些变化时，可植入医疗装置控制对患者神经系统的心脏相关部分的脊髓刺激和/或其它神经刺激的应用。 在一些实施例中，可植入医疗装置与独立的神经刺激装置通信以控制神经刺激。 在一些实施例中，可植入医疗装置递送神经刺激。