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公开(公告)号：US20110020473A1
公开(公告)日：2011-01-27
申请号：US12812705
申请日：2009-01-19
申请人： Norio Ogata , Takashi Shibata , Kazuhiko Taguchi , Koichi Doi
发明人： Norio Ogata , Takashi Shibata , Kazuhiko Taguchi , Koichi Doi
CPC分类号： A61K33/20 , A61K9/0034 , A61K9/08 , C01B11/022 , A61K2300/00
摘要： There are provided a chlorine dioxide solution composition whose solute includes dissolved chlorine dioxide and chlorite; and a solution composition encapsulating body including a glass vessel or enameled vessel and the chlorine dioxide solution composition hermetically sealed therein.
摘要翻译： 提供二氧化氯溶液组合物，其溶质包括溶解的二氧化氯和亚氯酸盐; 以及包含玻璃容器或搪瓷容器的溶液组合物封装体和密封在其中的二氧化氯溶液组合物。
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公开(公告)号：US08420129B2
公开(公告)日：2013-04-16
申请号：US12812705
申请日：2009-01-19
申请人： Norio Ogata , Takashi Shibata , Kazuhiko Taguchi , Koichi Doi
发明人： Norio Ogata , Takashi Shibata , Kazuhiko Taguchi , Koichi Doi
CPC分类号： A61K33/20 , A61K9/0034 , A61K9/08 , C01B11/022 , A61K2300/00
摘要： There are provided a chlorine dioxide solution composition whose solute includes dissolved chlorine dioxide and chlorite; and a solution composition encapsulating body including a glass vessel or enameled vessel and the chlorine dioxide solution composition hermetically sealed therein.
摘要翻译： 提供二氧化氯溶液组合物，其溶质包括溶解的二氧化氯和亚氯酸盐; 以及包含玻璃容器或搪瓷容器的溶液组合物封装体和密封在其中的二氧化氯溶液组合物。
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3.发明申请REPELLING AGENT, BITE REPELLING AGENT AND ARTHROPOD-BORNE DISEASE PREVENTIVE AGENT 审中-公开回转剂，BITE REPERING AGENT AND ARTHROPOD-BORNE DISEASE PREVENTTIVE AGENT公开(公告)号：US20110183004A1
公开(公告)日：2011-07-28
申请号：US12994458
申请日：2009-05-26
申请人： Hiroyuki Matsuoka , Norio Ogata , Takashi Shibata
发明人： Hiroyuki Matsuoka , Norio Ogata , Takashi Shibata
摘要： The invention provides a measure that can readily prevent arthropod-borne diseases such as malaria that are contracted by 3 to 5 hundred million people worldwide yearly and that cause death of as many as 1.5 to 2.7 million people. By spraying in advance on the skin an arthropod-borne disease preventive agent or the like comprising chlorine dioxide as an effective component thereof, it is possible to provide repelling effect against arthropods such as infected mosquitoes that bear malaria protozoa and also to prevent biting of the skin by the arthropod, thus reducing contraction of the arthropod-borne diseases.
摘要翻译： 本发明提供了一种措施，可以容易地预防全世界每年3亿至5亿人患有节肢动物传播疾病如疟疾，导致多达1.5至270万人死亡。 通过预先在皮肤上喷洒包含二氧化氯作为其有效成分的节肢动物传播疾病预防剂等，可以对节肢动物（例如感染了疟原虫的蚊子）提供排斥效果，并且还可防止咬合 节肢动物的皮肤，从而减少节肢动物传播的疾病的收缩。
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公开(公告)号：US6117913A
公开(公告)日：2000-09-12
申请号：US879072
申请日：1997-06-19
申请人： Akira Shibata , Takashi Shibata , Tomoo Kuge , Norio Ogata , Koji Ataka
发明人： Akira Shibata , Takashi Shibata , Tomoo Kuge , Norio Ogata , Koji Ataka
CPC分类号： A61K31/05 , A61K35/04 , Y10S514/867
摘要： An intestinal juice level regulator comprising, as the active ingredient, creosote or phenolic derivatives constituting creosote. As having the activities to promote the absorption of intestinal juices and/or to retard the secretion of intestinal juices, the active ingredient lowers the intestinal juice level in intestines. As the phenolic derivatives, usable are one or more of guaiacol, creosol, phenol, cresol and xylenol. The regulator is especially effective for retarding the hypersecretion of intestinal juices to be caused by heat-labile or heat-stable enterotoxin of enterotoxigenic Escherichia coli.
摘要翻译： 包含作为活性成分的构成杂酚油的杂酚油或酚衍生物的肠液液位调节剂。 由于具有促进肠液的吸收和/或延缓肠液分泌的活性，所以活性成分降低了肠内肠液中的水平。 作为酚类衍生物，可以使用愈创木酚，cre osol酚，苯酚，甲酚和二甲苯酚中的一种或多种。 调节剂对于阻止肠道致病性大肠杆菌的热不稳定或热稳定肠毒素引起的肠液的分泌过度特别有效。
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公开(公告)号：US5917031A
公开(公告)日：1999-06-29
申请号：US839608
申请日：1997-04-15
申请人： Takanori Miura , Norio Ogata
发明人： Takanori Miura , Norio Ogata
CPC分类号： C12Q1/6844 , C12N15/90 , C12P19/34
摘要： The invention relates to a method of synthesizing polydeoxyribonucleotides which comprises causing a thermostable deoxyribunucleotide polymerase to act on deoxyribonucleotides without using any template and any primers, to the thus-obtained polydeoxyribonucleotides, to a method of screening cDNA libraries using the same as probes, to a method comprising joining the DNA resulting from the above method of synthesis to the 3'--OH terminus of a double-stranded DNA containing a gene derived from cells of a living organism, followed by transfection of such cells with the product of joining and culture of the cells, to thereby cause insertion of the product into chromosomal DNA and production of the protein encoded by the gene, to a method of synthesizing chromosomal DNA and to a method of synthesizing chromosomes. According to the invention, it is possible to create DNA not occurring in the nature and create novel proteins using the thus created genes, hence means for providing novel physiologically or pharmacologically active substances can be provided.
摘要翻译： 本发明涉及一种合成多脱氧核糖核苷酸的方法，其包括使热稳定性脱氧核糖核苷酸聚合酶作用于脱氧核糖核苷酸，而不使用任何模板和任何引物，由此得到的多脱氧核糖核苷酸，使用与探针相同的筛选cDNA文库的方法， 方法包括将由上述合成方法得到的DNA连接到含有来源于活体细胞的基因的双链DNA的3'-OH末端，然后用连接和培养的产物转染该细胞 从而导致产物插入到染色体DNA中并产生由该基因编码的蛋白质，合成染色体DNA的方法和合成染色体的方法。 根据本发明，可以产生不存在于自然界中的DNA，并使用由此产生的基因产生新的蛋白质，因此可以提供提供新的生理学或药理学活性物质的手段。
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6.发明授权Polyarylene sulfide from aromatic compound having at least three functional groups 失效具有至少三个官能团的芳族化合物的聚芳硫醚
公开(公告)号：US5231163A
公开(公告)日：1993-07-27
申请号：US746819
申请日：1991-08-15
申请人： Wataru Kosaka , Minoru Senga , Norio Ogata , Tatsuya Housaki
发明人： Wataru Kosaka , Minoru Senga , Norio Ogata , Tatsuya Housaki
CPC分类号： C08G75/025 , C08G75/0222 , C08G75/0231 , C08K7/14
摘要： A polyarylene sulfide has an inherent viscosity [.eta..sub.i n h ] of 0.1 to 0.5 dl/g, a weight-average molecular weight of 1.times.10.sup.4 to 2.times.10.sup.5 ; a ratio of the inherent viscosity [.eta..sub.i n h ] to a calculated viscosity [.eta.].sub.calc ([.eta..sub.i n h /[.eta.].sub.calc) of 0.4/1 to 0.8/1; and a degree of whiteness of 50 or higher when measured in accordance with whiteness testing procedures (JIS P8123). The polyarylene sulfide is prepared by reaction by contacting at least one member of a metallic sulfide (A) selected from an alkali metal sulfide and an alkali metal hydrosulfide with a dihalogen aromatic compound (B) and an aromatic compound (C) having three or more than three functional groups in a polar solvent in a molar ratio of the dihalogen aromatic compound (B) to the metallic sulfide (A) [(B)/(A)] ranging from 1.035/1 to 1.300/1 and in a molar ratio of the aromatic compound (C) to the dihalogen aromatic compound (B) [(C)/(B)] ranging from 0.003/1 to 0.05/1.A polyarylene sulfide resin composition contains the polyarylene sulfide having the above properties and and at least one member of a filler selected from a fiber filler and a powdery or granular filler.The polyarylene sulfide resin composition has the mechanical strength, heat resistance, long-term stability, and chemical resistance superior to the polyarylene sulfide.
摘要翻译： 聚芳硫醚的特性粘度[η]为0.1〜0.5dl / g，重均分子量为1×10 4〜2×105; 特性粘度[η] h与计算出的粘度η（h /η/ calc）的比值为0.4 / 1至0.8 / 1; 并且根据白度测试程序（JIS P8123）测量时白度为50或更高。 通过使选自碱金属硫化物和碱金属氢硫化物的金属硫化物（A）的至少一种与二卤代芳香族化合物（B）和具有三个以上的碱金属硫化物的芳香族化合物（C）接触而使反应来制备聚芳硫醚 在极性溶剂中的三官能团，二卤代芳香族化合物（B）与金属硫化物（A）[（B）/（A）]的摩尔比为1.035 / 1〜1.300 / 1，摩尔比 的芳族化合物（C）与二卤代芳香族化合物（B）[（C）/（B）]的比例为0.003 / 1〜0.05 / 1。 聚芳硫醚树脂组合物含有具有上述性能的聚芳硫醚和至少一种选自纤维填料和粉末或颗粒填料的填料。 聚芳硫醚树脂组合物具有优于聚芳硫醚的机械强度，耐热性，长期稳定性和耐化学性。
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公开(公告)号：US07045664B2
公开(公告)日：2006-05-16
申请号：US10525528
申请日：2003-07-29
申请人： Kazuyuki Hirano , Norio Ogata
发明人： Kazuyuki Hirano , Norio Ogata
摘要： In a process for producing bisphenol A, an adduct of bisphenol A with phenol is promptly recovered in highly purity and high efficiency from a reaction mother liquor in the case of singling out bisphenol A from a reaction product. An adduct layer of bisphenol A with phenol is formed by crystallizing an adduct of bisphenol A with phenol from a solution of bisphenol A in phenol to form a slurry, the bisphenol A being produced by reacting phenol and acetone in the presence of an acid catalyst, subjecting the resultant slurry to a solid-liquid separation treatment, and thereafter removing the phenol from solid components, characterized by pouring onto a filter, a slurry solution of bisphenol A in phenol, the slurry solution containing in a crystalline state, an adduct of bisphenol A having an average particle size in the range of 0.05 to 1 mm with phenol, and filtering the slurry solution under reduced pressure in an atmosphere of an inert gas stream at 30 to 80° C. containing oxygen in a concentration of at most 5,000 ppm by volume.
摘要翻译： 在双酚A的制造方法中，在从反应产物中挑出双酚A的情况下，双酚A与苯酚的加合物能够以高纯度和高效率从反应母液中迅速回收。 双酚A与苯酚的加合物层通过在双酚A在苯酚中的溶液中结晶双酚A与苯酚的加合物形成浆料而形成，双酚A是通过使苯酚和丙酮在酸催化剂存在下反应生成的， 将所得浆料进行固液分离处理，然后从固体成分中除去苯酚，其特征在于将过滤器倾倒在双酚A在苯酚中的浆状溶液，含有结晶态的浆液，双酚的加合物 A的平均粒径在0.05〜1mm的范围内与苯酚反应，并在30〜80℃的惰性气体气氛中减压浓缩至多5000ppm的氧气过滤浆液 按体积计算。
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公开(公告)号：US20050222467A1
公开(公告)日：2005-10-06
申请号：US10508012
申请日：2003-03-19
申请人： Masahiro Kodama , Kazuyuki Hirano , Norio Ogata
发明人： Masahiro Kodama , Kazuyuki Hirano , Norio Ogata
摘要： In the process for producing bisphenol A comprising crystallizing an adduct of bisphenol A and phenol from a phenol solution of bisphenol A obtained by reacting phenol and acetone in the presence of an acid catalyst, treating the formed slurry by solid-liquid separation and removing phenol from the solid component, a layer of the crystalline adduct is formed on a filter by filtering slurry (1) comprising the crystalline adduct, washing the layer of the adduct with a washing liquid, dissolving the layer of the adduct in a solution comprising phenol, producing slurry (2) comprising the crystalline adduct by crystallization, and separating the crystalline adduct by centrifugation of slurry (2). When bisphenol A is separated from the reaction mixture, the adduct of bisphenol A and phenol can be recovered from the mother liquor of the reaction efficiently at a high purity in accordance with the above process.
摘要翻译： 在生产双酚A的方法中，包括在酸催化剂存在下，通过苯酚和丙酮反应得到的双酚A的苯酚溶液中结晶双酚A和苯酚的加合物，通过固液分离处理形成的浆料并除去酚 通过过滤包含结晶加合物的浆料（1）在洗涤液上形成一层结晶加合物，用洗涤液洗涤加合物层，将加合物层溶解在包含苯酚的溶液中，产生 浆料（2）通过结晶包含结晶加合物，并通过离心浆料（2）分离结晶加合物。 当从反应混合物中分离出双酚A时，根据上述方法，双酚A和苯酚的加合物能够以高纯度有效地从反应的母液中回收。
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公开(公告)号：US5635587A
公开(公告)日：1997-06-03
申请号：US357405
申请日：1994-12-16
申请人： Yoshinari Koyama , Norio Ogata , Hiroshi Nishitani
发明人： Yoshinari Koyama , Norio Ogata , Hiroshi Nishitani
CPC分类号： C01D3/18 , C01D3/14 , C08G75/025 , C08G75/0254 , C08G75/0259 , C08G75/0272 , C08G75/0281
摘要： A process for efficiently manufacturing high purity polyarylene sulfide. The process comprises feeding a liquid or gaseous sulfur compound (e.g. hydrogen sulfide) to a mixture comprising lithium hydroxide and a non-lithium hydroxide solid compound (e.g. alkali metal chloride or alkaline earth metal chloride) in a non-protonic organic solvent (e.g. N-methyl-2-pyrrolidone), separating the alkali metal chloride or alkaline earth metal chloride, adjusting the sulfur content of the reaction mixture, feeding a dihalogeno aromatic compound e.g. p-dichlorobenzene) to effect a polycondensation reaction, and adding of an alkali metal hydroxide (e.g. sodium hydroxide) to recover lithium ion.
摘要翻译： 一种有效制造高纯度聚芳硫醚的方法。 该方法包括在包含氢氧化锂和非氢氧化锂固体化合物（例如碱金属氯化物或碱土金属氯化物）的混合物中将液体或气态硫化合物（例如硫化氢）供入非质子有机溶剂（例如N - 甲基-2-吡咯烷酮），分离碱金属氯化物或碱土金属氯化物，调节反应混合物的硫含量，加入二卤代芳族化合物，例如 对二氯苯）进行缩聚反应，加入碱金属氢氧化物（如氢氧化钠）回收锂离子。
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公开(公告)号：US4919911A
公开(公告)日：1990-04-24
申请号：US285031
申请日：1988-12-16
申请人： Daigo Shirota , Masao Omori , Hiroyasu Yamato , Norio Ogata
发明人： Daigo Shirota , Masao Omori , Hiroyasu Yamato , Norio Ogata
CPC分类号： C01D15/04 , C08G75/0281
摘要： The present invention provides a method of recovering a lithium chloride, which comprises reacting a dihalogenated aromatic compound and an alkali metal sulfide and/or alkali metal hydrogen sulfide in a polar solvent under the pressure of lithium chloride, separating a solvent insoluble component from the resultant reaction mixture to obtain a solution, and calcinating a residue obtained by removing volatile substances from the resultant solution, as well as a method of recovering a lithium chloride, which comprises reacting a dihalogenated aromatic compound and an alkali metal sulfide and/or alkali metal hydrogen sulfide in a polar solvent under the pressure of lithium chloride, separating the granular polymer ingredient from the resultant reaction mixture subjecting the liquid suspension obtained by said separation to solid-liquid separation and calcinating the residue obtained by removing volatile substances from the resultant solution component.
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