-
公开(公告)号:US20180243243A1
公开(公告)日:2018-08-30
申请号:US15949736
申请日:2018-04-10
申请人: Nevakar, Inc.
发明人: Vivek Yadav , Sriramya Garapati , Tushar Hingorani , Iouri V. Ilitchev , Prem Sagar Akasapu , Kumaresh Soppimath , Navneet Puri
IPC分类号: A61K31/137 , A61K9/00 , A61P9/02
CPC分类号: A61K31/137 , A61K9/0019 , A61K47/12 , A61K47/183 , A61P9/02
摘要: The inventive subject matter is directed to compositions and methods for ready-to-inject norepinephrine compositions with improved stability. Most preferably, compositions presented herein are substantially antioxidant free and exhibit less than 10% isomerization of R-nor epinephrine and exhibit less than 5% degradation of total norepinephrine.
-
公开(公告)号:US10052296B2
公开(公告)日:2018-08-21
申请号:US15482196
申请日:2017-04-07
申请人: Nevakar Inc.
发明人: Varun Khurana , Vivek Yadav , Jack Martin Lipman , Tao Zhang , Iouri V. Ilitchev , Tushar Hingorani , Kumaresh Soppimath , Navneet Puri
IPC分类号: A61K31/195 , A61K9/00 , A61K31/167 , A61K45/06
CPC分类号: A61K31/195 , A61K9/0019 , A61K31/167 , A61K31/197 , A61K45/06 , A61K2300/00
摘要: Formulations, methods of manufacturing, methods of stabilizing, kits, and uses as medicament are provided, for example for the treatment of pain. The formulations can comprise gabapentin optionally combined with at least one non-opioid pain drug in an aqueous carrier. The pharmaceutical formulation can have a pH of about 2.0 to about 10.0. The at least one non-opioid pain drug can be acetaminophen. The components can be included in any amount suitable for purposes of obtaining properties desirable for an injectable infusion, for example an intravenous infusion.
-
公开(公告)号:US20210169897A1
公开(公告)日:2021-06-10
申请号:US16769204
申请日:2018-12-06
申请人: Nevakar Inc.
发明人: Vivek Yadav , Sriramya Garapati , Bronislava Zektser , Varun Khurana , Iouri V Ilitchev , Prem Sagar Akasapu , Tushar Hingorani , Kumaresh Soppimath , Navneet Puri
摘要: Compositions and methods for injectable and liquid fulvestrant formulations that have fulvestrant at a relatively high concentration stably solubilized before and after injection of the patient are provided.
-
公开(公告)号:US10226436B2
公开(公告)日:2019-03-12
申请号:US15883798
申请日:2018-01-30
申请人: Nevakar Inc.
发明人: Navneet Puri , Kumaresh Soppimath , Prem Sagar Akasapu , Vivek Yadav , Iouri V. Ilitchev , Sriramya Garapati , Tushar Hingorani
IPC分类号: A61K31/137 , A61P9/02 , A61K47/12 , A61K47/18 , A61K9/00
摘要: The inventive subject matter is directed to compositions and methods for ready-to-inject norepinephrine compositions with improved stability. Most preferably, compositions presented herein are substantially antioxidant free and exhibit less than 10% isomerization of R-norepinephrine and exhibit less than 5% degradation of total norepinephrine.
-
公开(公告)号:US20210128507A1
公开(公告)日:2021-05-06
申请号:US17098923
申请日:2020-11-16
申请人: NEVAKAR Inc.
发明人: Varun Khurana , Vivek Yadav , Jack Martin Lipman , Tao Zhang , Iouri V. Ilitchev , Tushar Hingorani , Kumaresh Soppimath , Navneet Puri
IPC分类号: A61K31/195 , A61K9/00 , A61K31/167 , A61K45/06 , A61K31/197
摘要: Formulations, methods of manufacturing, methods of stabilizing, kits, and uses as medicament are provided, for example for the treatment of pain. The formulations can comprise gabapentin optionally combined with at least one non-opioid pain drug in an aqueous carrier. The pharmaceutical formulation can have a pH of about 2.0 to about 10.0. The at least one non-opioid pain drug can be acetaminophen. The components can be included in any amount suitable for purposes of obtaining properties desirable for an injectable infusion, for example an intravenous infusion.
-
公开(公告)号:US10159657B2
公开(公告)日:2018-12-25
申请号:US15949736
申请日:2018-04-10
申请人: Nevakar, Inc.
发明人: Vivek Yadav , Sriramya Garapati , Tushar Hingorani , Iouri V. Ilitchev , Prem Sagar Akasapu , Kumaresh Soppimath , Navneet Puri
IPC分类号: A61K31/137 , A61P9/02 , A61K47/12 , A61K47/18 , A61K9/00
摘要: The inventive subject matter is directed to compositions and methods for ready-to-inject norepinephrine compositions with improved stability. Most preferably, compositions presented herein are substantially antioxidant free and exhibit less than 10% isomerization of R-nor epinephrine and exhibit less than 5% degradation of total norepinephrine.
-
公开(公告)号:US20180214394A1
公开(公告)日:2018-08-02
申请号:US15883798
申请日:2018-01-30
申请人: Nevakar, Inc.
发明人: Navneet Puri , Kumaresh Soppimath , Prem Sagar Akasapu , Vivek Yadav , Iouri V. Ilitchev , Sriramya Garapati , Tushar Hingorani
IPC分类号: A61K31/137 , A61K9/00 , A61P9/02
CPC分类号: A61K31/137 , A61K9/0019 , A61K47/12 , A61K47/183 , A61P9/02
摘要: The inventive subject matter is directed to compositions and methods for ready-to-inject norepinephrine compositions with improved stability. Most preferably, compositions presented herein are substantially antioxidant free and exhibit less than 10% isomerization of R-norepinephrine and exhibit less than 5% degradation of total norepinephrine.
-
-
-
-
-
-