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公开(公告)号：US10251875B2
公开(公告)日：2019-04-09
申请号：US15976279
申请日：2018-05-10
申请人： Nevakar Inc.
发明人： Navneet Puri , Prem Sagar Akasapu , Irfan A. Mohammed , Kumaresh Soppimath , Iouri V. Ilitchev , Tao Zhang
摘要： The inventive subject matter is directed to compositions and methods for sterile and storage stable low-dose atropine formulations with improved stability. Most preferably, the compositions presented herein are substantially preservative free and exhibit less than 0.35% tropic acid from degradation of atropine. Advantageously, contemplated formulations are also substantially free of preservatives.
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公开(公告)号：US20180325888A1
公开(公告)日：2018-11-15
申请号：US15976279
申请日：2018-05-10
申请人： Nevakar Inc.
发明人： Navneet Puri , Prem Sagar Akasapu , Irfan A. Mohammed , Kumaresh Soppimath , Iouri V. Ilitchev , Tao Zhang
CPC分类号： A61K31/46 , A61K9/0048 , A61K9/08 , A61K47/02 , A61K47/183 , A61K47/38
摘要： The inventive subject matter is directed to compositions and methods for sterile and storage stable low-dose atropine formulations with improved stability. Most preferably, the compositions presented herein are substantially preservative free and exhibit less than 0.35% tropic acid from degradation of atropine. Advantageously, contemplated formulations are also substantially free of preservatives.
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公开(公告)号：US10052296B2
公开(公告)日：2018-08-21
申请号：US15482196
申请日：2017-04-07
申请人： Nevakar Inc.
发明人： Varun Khurana , Vivek Yadav , Jack Martin Lipman , Tao Zhang , Iouri V. Ilitchev , Tushar Hingorani , Kumaresh Soppimath , Navneet Puri
IPC分类号： A61K31/195 , A61K9/00 , A61K31/167 , A61K45/06
CPC分类号： A61K31/195 , A61K9/0019 , A61K31/167 , A61K31/197 , A61K45/06 , A61K2300/00
摘要： Formulations, methods of manufacturing, methods of stabilizing, kits, and uses as medicament are provided, for example for the treatment of pain. The formulations can comprise gabapentin optionally combined with at least one non-opioid pain drug in an aqueous carrier. The pharmaceutical formulation can have a pH of about 2.0 to about 10.0. The at least one non-opioid pain drug can be acetaminophen. The components can be included in any amount suitable for purposes of obtaining properties desirable for an injectable infusion, for example an intravenous infusion.
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公开(公告)号：US20190133981A1
公开(公告)日：2019-05-09
申请号：US16091614
申请日：2017-04-07
申请人： NEVAKAR INC
发明人： Varun KHURANA , Vlvek Yadav , Jack Martin Lipman , Tao Zhang , Iouri V. Illtchev , Tushar Hingorani , Navneet Puri , Kumaresh Soppimath
IPC分类号： A61K31/195 , A61K9/00 , A61K31/197 , A61K31/167
摘要： Formulations, methods of manufacturing, methods of stabilizing, kits, and uses as medicament are provided, for example for the treatment of pain. The formulations can comprise gabapentin optionally combined with at least one non-opioid pain drug in an aqueous carrier. The pharmaceutical formulation can have a pH of about 2.0 to about 10.0. The at least one non-opioid pain drug can be acetaminophen. The components can be included in any amount suitable for purposes of obtaining properties desirable for an injectable infusion, for example an intravenous infusion.
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公开(公告)号：US20210128507A1
公开(公告)日：2021-05-06
申请号：US17098923
申请日：2020-11-16
申请人： NEVAKAR Inc.
发明人： Varun Khurana , Vivek Yadav , Jack Martin Lipman , Tao Zhang , Iouri V. Ilitchev , Tushar Hingorani , Kumaresh Soppimath , Navneet Puri
IPC分类号： A61K31/195 , A61K9/00 , A61K31/167 , A61K45/06 , A61K31/197
摘要： Formulations, methods of manufacturing, methods of stabilizing, kits, and uses as medicament are provided, for example for the treatment of pain. The formulations can comprise gabapentin optionally combined with at least one non-opioid pain drug in an aqueous carrier. The pharmaceutical formulation can have a pH of about 2.0 to about 10.0. The at least one non-opioid pain drug can be acetaminophen. The components can be included in any amount suitable for purposes of obtaining properties desirable for an injectable infusion, for example an intravenous infusion.
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