公开(公告)号：US20210169897A1

公开(公告)日：2021-06-10

申请号：US16769204

申请日：2018-12-06

申请人： Nevakar Inc.

发明人： Vivek Yadav ,  Sriramya Garapati ,  Bronislava Zektser ,  Varun Khurana ,  Iouri V Ilitchev ,  Prem Sagar Akasapu ,  Tushar Hingorani ,  Kumaresh Soppimath ,  Navneet Puri

IPC分类号： A61K31/565 ,  A61K9/00 ,  A61K9/08 ,  A61K47/12 ,  A61K47/14 ,  A61K47/44

摘要： Compositions and methods for injectable and liquid fulvestrant formulations that have fulvestrant at a relatively high concentration stably solubilized before and after injection of the patient are provided.

公开(公告)号：US10052296B2

公开(公告)日：2018-08-21

申请号：US15482196

申请日：2017-04-07

申请人： Nevakar Inc.

发明人： Varun Khurana ,  Vivek Yadav ,  Jack Martin Lipman ,  Tao Zhang ,  Iouri V. Ilitchev ,  Tushar Hingorani ,  Kumaresh Soppimath ,  Navneet Puri

IPC分类号： A61K31/195 ,  A61K9/00 ,  A61K31/167 ,  A61K45/06

CPC分类号： A61K31/195 ,  A61K9/0019 ,  A61K31/167 ,  A61K31/197 ,  A61K45/06 ,  A61K2300/00

摘要： Formulations, methods of manufacturing, methods of stabilizing, kits, and uses as medicament are provided, for example for the treatment of pain. The formulations can comprise gabapentin optionally combined with at least one non-opioid pain drug in an aqueous carrier. The pharmaceutical formulation can have a pH of about 2.0 to about 10.0. The at least one non-opioid pain drug can be acetaminophen. The components can be included in any amount suitable for purposes of obtaining properties desirable for an injectable infusion, for example an intravenous infusion.

公开(公告)号：US20210128507A1

公开(公告)日：2021-05-06

申请号：US17098923

申请日：2020-11-16

申请人： NEVAKAR Inc.

发明人： Varun Khurana ,  Vivek Yadav ,  Jack Martin Lipman ,  Tao Zhang ,  Iouri V. Ilitchev ,  Tushar Hingorani ,  Kumaresh Soppimath ,  Navneet Puri

IPC分类号： A61K31/195 ,  A61K9/00 ,  A61K31/167 ,  A61K45/06 ,  A61K31/197

摘要： Formulations, methods of manufacturing, methods of stabilizing, kits, and uses as medicament are provided, for example for the treatment of pain. The formulations can comprise gabapentin optionally combined with at least one non-opioid pain drug in an aqueous carrier. The pharmaceutical formulation can have a pH of about 2.0 to about 10.0. The at least one non-opioid pain drug can be acetaminophen. The components can be included in any amount suitable for purposes of obtaining properties desirable for an injectable infusion, for example an intravenous infusion.

公开(公告)号：US20200246294A1

公开(公告)日：2020-08-06

申请号：US16644022

申请日：2018-09-27

申请人： Nevakar Inc.

发明人： Varun Khurana ,  Tushar Hingorani ,  Jack Martin Lipman ,  Kumaresh Soppimath

IPC分类号： A61K31/197 ,  A61K31/167 ,  A61K31/192 ,  A61K45/06

摘要： Fixed-dose combination drugs comprising an NSAID as a first drug component and a GABA-type calcium channel blocker as a second drug component are contemplated. Further contemplated aspects also include methods of administration of combination drugs and drugs contained herein.