公开(公告)号：US12012593B2

公开(公告)日：2024-06-18

申请号：US17727975

申请日：2022-04-25

Applicant: Miti Biosystems GmbH

Inventor： Guntram Christiansen

IPC: C40B40/02 ,  C07K1/04 ,  C12N15/10 ,  C40B40/10 ,  C40B50/06

CPC classification number: C12N15/1037 ,  C07K1/047 ,  C12N15/1082 ,  C40B40/02 ,  C40B40/10 ,  C40B50/06

Abstract: The invention refers to a replicable genetic package displaying a peptide having at least one intramolecular cyclic bond between two heteroatoms of amino acid side chains, a method of preparing a replicable genetic package, a method of producing a library and a library of replicable genetic package.

公开(公告)号：US11332734B2

公开(公告)日：2022-05-17

申请号：US16361099

申请日：2019-03-21

Applicant: Miti Biosystems GmbH

Inventor： Guntram Christiansen

IPC: C40B40/10 ,  C12N15/10 ,  C40B40/02 ,  C07K1/04 ,  C40B50/06

Abstract: The invention provides a replicable genetic package displaying a cyclic peptide having at least one intramolecular bond between amino acid side chains. Also provided are a method of preparing such a genetic package displaying cyclic peptides having at least one intramolecular bond. Further provided is a library of replicable genetic packages displaying cyclic peptides each having at least one intramolecular cyclic bond between amino acid side chains; and a method of producing such a library.