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公开(公告)号：US20240023849A1
公开(公告)日：2024-01-25
申请号：US18344273
申请日：2023-06-29
IPC分类号： A61B5/1486 , A61B5/145
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/14546
摘要： Embodiments of the invention provide compositions useful in implantable devices such as analyte sensors as well as methods for making and using such compositions and devices. In typical embodiments of the invention, the device is a glucose sensor comprising an analyte modulating layer formed from acrylate hydrogel composition that modulates the diffusion of glucose through the analyte modulating layer and which further comprises a bioactive agent selected to enhance the biocompatibility of analyte sensors when implanted in vivo.
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公开(公告)号：US20170248542A1
公开(公告)日：2017-08-31
申请号：US15595687
申请日：2017-05-15
发明人： Steven C. Jacks , Raghavendhar Gautham , Bradley C. Liang , Megan E. Little , Daniel E. Pesantez , Rajiv Shah
IPC分类号： G01N27/416 , A61B5/145
CPC分类号： G01N27/416 , A61B5/1451 , A61B5/14532 , A61B2562/02 , A61B2562/125 , C23C28/00 , C25D3/52 , C25D3/567 , C25D5/18 , C25D7/00 , G01N27/30 , G01N27/327
摘要： A physiological characteristic sensor, a method for forming a physiological characteristic sensor, and a method for forming a platinum deposit having a rough surface are presented here. The method for forming a physiological characteristic sensor includes immersing a sensor electrode in a platinum electrolytic bath. Further, the method includes performing an electrodeposition process by sequentially applying a pulsed signal to the sensor electrode, wherein the pulsed signal includes a repeated cycle of a first current and a second current different from the first current, and applying a non-pulsed continuous signal to the sensor electrode, wherein the non-pulsed continuous signal includes a non-repeated application of a third current, to form a platinum deposit on the sensor electrode.
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公开(公告)号：US20240358294A1
公开(公告)日：2024-10-31
申请号：US18763620
申请日：2024-07-03
发明人： Jia Yao , Daniel E. Pesantez , Anuradha Biswas Bhatia , Akhil Srinivasan , Guangping Zhang , Andrea Varsavsky , Raghavendhar Gautham
IPC分类号： A61B5/1486 , A61B5/00 , A61B5/145 , A61L31/04 , A61L31/14 , C09D5/16 , C12Q1/00 , C12Q1/26 , C12Q1/54
CPC分类号： A61B5/14865 , A61B5/1451 , A61B5/14532 , A61L31/04 , A61L31/14 , C09D5/1681 , C12Q1/006 , C12Q1/26 , C12Q1/54 , A61B5/41 , A61L2400/18
摘要： Embodiments of the invention provide optimized polymeric surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These polymer surfaces have a constellation of features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a polymer surface with the disclosed constellation of features.
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公开(公告)号：US20220240823A1
公开(公告)日：2022-08-04
申请号：US17162885
申请日：2021-01-29
发明人： Ashwin K. Rao , Qingling Yang , Ellis Garai , Daniel E. Pesantez
IPC分类号： A61B5/1486 , A61B5/145
摘要： Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes, and associated architectures, as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.
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5.发明申请公开(公告)号：US20190274600A1
公开(公告)日：2019-09-12
申请号：US16241591
申请日：2019-01-07
IPC分类号： A61B5/145 , A61B5/1486 , C12Q1/00
摘要： Embodiments of the invention provide analyte sensors having optimized electrodes and/or configurations of electrode elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.
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公开(公告)号：US11642454B2
公开(公告)日：2023-05-09
申请号：US16893145
申请日：2020-06-04
发明人： Chia-Hung Chiu , Rebecca K. Gottlieb , Ellis Garai , Akhil Srinivasan , Andrea Varsavsky , Adam S. Trock , Ashwin K. Rao , Hsifu Wang , Daniel E. Pesantez , Isabella Ella Miya , Xinrui Zhang , Guruguhan Meenakshisundaram
CPC分类号： A61M5/14248 , A61M5/162 , A61M5/16831 , A61M5/1723 , A61M37/0015 , A61M39/10 , A61M2005/14252 , A61M2037/0023 , A61M2205/50 , A61M2205/8206 , A61M2205/8243 , A61M2230/201
摘要： A fluid infusion system includes a housing configured to be adhesively coupled to an anatomy of the user. The housing comprises a communication device configured to wirelessly communicate a physiological characteristic to a communication component of a fluid infusion device. The fluid infusion system includes a fluid flow path from the fluid infusion device into the anatomy of the user, and the fluid flow path is configured to extend from the housing for insertion into the anatomy of the user.
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公开(公告)号：US20210024972A1
公开(公告)日：2021-01-28
申请号：US16523882
申请日：2019-07-26
发明人： Daniel E. Pesantez , Ashwin K. Rao , Ellis Garai , Rui Kong , Michael E. Miller
IPC分类号： C12Q1/00 , A61B5/145 , A61B5/1486 , G01N27/327
摘要： Embodiments of the invention provide multilayer analyte sensors having elements and/or architectures that function to improve oxygen delivery to sensor enzymes in manner that enhances sensor function, as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.
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公开(公告)号：US09681828B2
公开(公告)日：2017-06-20
申请号：US14267739
申请日：2014-05-01
发明人： Steven C. Jacks , Raghavendhar Gautham , Bradley C. Liang , Megan E. Little , Daniel E. Pesantez , Rajiv Shah
CPC分类号： G01N27/416 , A61B5/1451 , A61B5/14532 , A61B2562/02 , A61B2562/125 , C23C28/00 , C25D3/52 , C25D3/567 , C25D5/18 , C25D7/00 , G01N27/30 , G01N27/327
摘要： A physiological characteristic sensor, a method for forming a physiological characteristic sensor, and a method for forming a platinum deposit having a rough surface are presented here. The method for forming a physiological characteristic sensor includes immersing a sensor electrode in a platinum electrolytic bath. Further, the method includes performing an electrodeposition process by sequentially applying a pulsed signal to the sensor electrode and applying a non-pulsed continuous signal to the sensor electrode to form a platinum deposit on the sensor electrode.
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9.发明申请MICROARRAY ELECTRODES USEFUL WITH ANALYTE SENSORS AND METHODS FOR MAKING AND USING THEM 审中-公开具有分析仪传感器的MICROARRAY电极及其制造和使用方法公开(公告)号：US20140163346A1
公开(公告)日：2014-06-12
申请号：US13707400
申请日：2012-12-06
CPC分类号： A61B5/14532 , A61B5/14865 , A61B2562/028 , A61B2562/046 , C12Q1/006
摘要： Embodiments of the invention provide analyte sensors having optimized electrodes and/or configurations of electrode elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.
摘要翻译： 本发明的实施例提供具有优化的电极和/或电极元件的构造的分析物传感器以及用于制造和使用这种传感器的方法。 本发明的典型实施方案包括用于治疗糖尿病的葡萄糖传感器。
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公开(公告)号：US12042284B2
公开(公告)日：2024-07-23
申请号：US15878313
申请日：2018-01-23
发明人： Jia Yao , Daniel E. Pesantez , Anuradha Biswas Bhatia , Akhil Srinivasan , Guangping Zhang , Andrea Varsavsky , Raghavendhar Gautham
IPC分类号： A61B5/1486 , A61B5/145 , A61L31/04 , A61L31/14 , C09D5/16 , C12Q1/00 , C12Q1/26 , C12Q1/54 , A61B5/00
CPC分类号： A61B5/14865 , A61B5/1451 , A61B5/14532 , A61L31/04 , A61L31/14 , C09D5/1681 , C12Q1/006 , C12Q1/26 , C12Q1/54 , A61B5/41 , A61L2400/18
摘要： Embodiments of the invention provide optimized polymeric surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These polymer surfaces have a constellation of features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a polymer surface with the disclosed constellation of features.
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