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公开(公告)号：US20240174959A1
公开(公告)日：2024-05-30
申请号：US18392583
申请日：2023-12-21
发明人： Shoji FURUSAKO , Tsutomu SATOH , Tomohiro NARUMI , Shingo SATO
CPC分类号： C12M25/10 , C08L5/04 , C12M23/20 , C12N5/0676 , C12N5/0682
摘要： There has been demand for an additional method for producing antibodies. The present invention provides: a polymer-coated crosslinked alginate gel fiber in which a core layer containing a crosslinked alginate gel and either antibody-producing cells (e.g., antibody-producing CHO cells) or bioactive-substance-producing cells (e.g., MIN6 cells derived from pancreatic β cells) is coated with a cationic polymer; and a method for producing antibodies, a bioactive substance, etc., using the fiber.
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公开(公告)号：US20240132854A1
公开(公告)日：2024-04-25
申请号：US18269705
申请日：2021-12-27
发明人： Shoji FURUSAKO , Naoto TSUDA , Tsutomu SATOH , Tomohiro NARUMI , Shingo SATO
CPC分类号： C12N5/10 , C07K16/2803 , C08B37/0084 , C12N2533/30 , C12N2533/32 , C12N2533/74 , C12N2535/00 , C12N2537/10
摘要： There has been demand for an additional method for producing antibodies. The present invention provides: a polymer-coated crosslinked alginate gel fiber in which a core layer containing a crosslinked alginate gel and either antibody-producing cells (e.g., antibody-producing CHO cells) or bioactive-substance-producing cells (e.g., MIN6 cells derived from pancreatic β cells) is coated with a cationic polymer; and a method for producing antibodies, a bioactive substance, etc., using the fiber.
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