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1.发明授权公开(公告)号：US09856271B2
公开(公告)日：2018-01-02
申请号：US15113080
申请日：2015-01-20
Applicant: Laurus Labs Private Limited
Inventor： Satyanarayana Chava , Seeta Rama Anjaneyulu Gorantla , Venkata Lakshmi Narasimha Dammalapati , Mani Bushan Kotala , Ravindra Aduri
IPC: C07D498/14 , C07D213/82 , C07D317/30 , C07D319/06 , C07C235/80 , C07C237/16
CPC classification number: C07D498/14 , C07B2200/13 , C07C235/80 , C07C237/16 , C07D213/82 , C07D317/30 , C07D319/06
Abstract: The present invention relates to a novel process for the preparation of dolutegravir and pharmaceutically acceptable salts thereof using novel intermediates.
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2.发明授权Salts of sitagliptin, process for the preparation and pharmaceutical composition therefore 有权西他列汀的盐，因此制备方法和药物组合物公开(公告)号：US09181256B2
公开(公告)日：2015-11-10
申请号：US13985490
申请日：2012-10-12
Applicant: Laurus Labs Private Limited
Inventor： Venkata Sunil Kumar Indukuri , Seeta Ramanjaneyulu Gorantla , Vamsee Krishna Muppidi , Satyanarayana Chava
IPC: C07D487/04 , A61K31/4985 , C07C57/42
CPC classification number: C07C57/42 , A61K31/4985 , C07D487/04
Abstract: The present invention relates to pharmaceutically acceptable acid addition salts of sitagliptin, in particular anti-oxidant acid addition salts of sitagliptin and a process for its preparation. The present invention also provides a pharmaceutical composition using the pharmaceutically acceptable acid addition salts of sitagliptin.
Abstract translation: 本发明涉及西格列汀的药学上可接受的酸加成盐，特别是西格列汀的抗氧化酸加成盐及其制备方法。 本发明还提供了使用西格列汀的药学上可接受的酸加成盐的药物组合物。
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3.发明申请PROCESS FOR THE PREPARATION OF POLYHYDROXYSTILBENE COMPOUNDS BY DEPROTECTION OF THE CORRESPONDING ETHERS 有权通过去除相关物质来制备聚羟基苯乙烯化合物的方法公开(公告)号：US20150031921A1
公开(公告)日：2015-01-29
申请号：US14353869
申请日：2012-11-30
Applicant: LAURUS LABS PRIVATE LIMITED
Inventor： Harish Niranjanlal Dorwal , Sandirane Sabapathy , Seeta Raman Gorantla , Satyanarayana Chava
IPC: C07C37/055
CPC classification number: C07C37/055 , C07C39/23
Abstract: A process for the preparation of polyhydroxystilbene compounds (particularly resveratrol, oxyresveratrol, piceatannol, gnetol and the like) by deprotection of the corresponding ethers using aluminium halide and a secondary amine is provided.
Abstract translation: 提供了通过使用卤化铝和仲胺对相应的醚进行脱保护来制备多羟基茋化合物（特别是白藜芦醇，氧基白藜芦醇，吡哆醇，胶体等）的方法。
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公开(公告)号：US20170313662A1
公开(公告)日：2017-11-02
申请号：US15516206
申请日：2015-10-01
Applicant: Laurus Labs Private Limited
Inventor： Kameswar Rao Chivukula , Veera Karuturi , Rao Venkateswara , Srinivas Benda , Ramachandra Anke , Dharmapuri Gajula , Venkata Rama Krishna Murt Moturu , Venkata Sunil Kumar Indukuri , Seeta Rama Anjaneyulu Gorantla , Satyanarayana Chava
IPC: C07D233/86 , C07C25/13 , C07C22/08 , C07C331/28 , C07C255/49 , C07C2601/16
CPC classification number: C07D233/86 , C07C22/08 , C07C25/13 , C07C255/49 , C07C331/28 , C07C333/08 , C07C335/22 , C07C335/26 , C07C2601/16
Abstract: The present invention relates to an improved process for the preparation of enzalutamide by conventional synthesis, which avoids utilization of microwave irradiation and noxious reagents. The present invention also relates to an improved process for preparation of 4-isothiocyanato-2-(trifluoromethyl) benzonitrile, which is an intermediate in the synthesis of Enzalutamide.
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公开(公告)号：US10730859B2
公开(公告)日：2020-08-04
申请号：US15034797
申请日：2014-11-05
Applicant: Laurus Labs Private Limited
Inventor： Satyanarayana Chava , Seeta Rama Anjaneyulu Gorantla , Venkata Sunil Kumar Indukuri , Sanjay Kumar Dehury , Nagaraju Mekala , Jahangeer Baba Shaik , Durga Prasad Kuchipudi
IPC: C07D403/12
Abstract: The present invention is relates to an improved process for the preparation of pazopanib or a pharmaceutically acceptable salts thereof. The present invention also relates to novel polymorphic Forms of pazopanib hydrochloride, and its intermediates thereof.
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Patent Agency Ranking
6.发明授权公开(公告)号：US10364269B2
公开(公告)日：2019-07-30
申请号：US15573912
申请日：2016-05-21
Applicant: LAURUS LABS PRIVATE LIMITED
Inventor： Sanjay Kumar Dehury , Nagaraju Mekala , Jahangeer Baba Shaik , Srinivasa Rao Buddepu , Lakshmi Kanth Kola , Venkata Sunil Kumar Indukuri , Seeta Rama Anjaneyulu Gorantla , Satyanarayana Chava
IPC: C07K5/103 , A61K47/42 , C07C271/22 , C07D303/36 , C07C271/16 , C07C271/18 , A61K9/00 , A61K38/07
Abstract: The present invention relates to an improved process for the preparation of carfilzomib or a pharmaceutically acceptable salt thereof. The present invention also relates to a process for the preparation of amorphous form of carfilzomib.
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7.发明申请公开(公告)号：US20190085026A1
公开(公告)日：2019-03-21
申请号：US15573912
申请日：2016-05-21
Applicant: LAURUS LABS PRIVATE LIMITED
Inventor： Sanjay Kumar Dehury , Nagaraju Mekala , Jahangeer Baba Shaik , Srinivasa Rao Buddepu , Lakshmi Kanth Kola , Venkata Sunil Kumar Indukuri , Seeta Rama Anjaneyulu Gorantla , Satyanarayana Chava
IPC: C07K5/103
CPC classification number: C07K5/1008 , A61K9/0019 , A61K38/07 , C07C271/16 , C07C271/18 , C07C271/22 , C07D303/36
Abstract: The present invention relates to an improved process for the preparation of carfilzomib or a pharmaceutically acceptable salt thereof. The present invention also relates to a process for the preparation of amorphous form of carfilzomib.
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公开(公告)号：US20180244622A1
公开(公告)日：2018-08-30
申请号：US15755436
申请日：2016-09-02
Applicant: LAURUS LABS PRIVATE LIMITED
Inventor： Suresh Thatipally , Venkata Krishna Reddy , Venkata Lakshmi Narasimha Rao Dammalapati , Satyanarayana Chava
IPC: C07D215/56 , C07C235/80 , C07C237/20
CPC classification number: C07D215/56 , A61K31/47 , C07C235/80 , C07C237/20
Abstract: The present invention provides processes for the preparation of ivacaftor using novel intermediates and a process for its preparation.
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公开(公告)号：US09573902B2
公开(公告)日：2017-02-21
申请号：US14768082
申请日：2014-02-14
Applicant: Laurus Labs Private Limited
Inventor： Suresh Thatipally , Venkata Lakshmi Narasimha Rao Dammalapati , Seeta Ramanjaneyulu Gorantla , Satyanarayana Chava
IPC: A61K31/47 , C07D215/56 , C07D215/48 , C07C227/14 , C07C227/18 , C07C229/30
CPC classification number: C07D215/56 , A61K31/47 , C07C227/14 , C07C227/18 , C07C229/30 , C07D215/48 , C07C229/34
Abstract: The present invention provides novel intermediates of ivacaftor and process for its preparation. The present invention also provides process for the preparation of ivacaftor and pharmaceutically acceptable salt thereof using novel intermediates.
Abstract translation: 本发明提供了新颖的ivacaftor的中间体及其制备方法。 本发明还提供了使用新型中间体制备叶斑病及其药学上可接受的盐的方法。
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10.发明授权Salts of sitagliptin, process from the preparation and pharmaceutical composition therefore 有权西他列汀的盐，因此从制剂和药物组合物的过程公开(公告)号：US09388113B2
公开(公告)日：2016-07-12
申请号：US14872210
申请日：2015-10-01
Applicant: Laurus Labs Private Limited
Inventor： Venkata Sunil Kumar Indukuri , Seeta Ramanjaneyulu Gorantla , Vamsee Krishna Muppidi , Satyanarayana Chava
IPC: C07C57/44 , C07C57/42 , C07D487/04
CPC classification number: C07C57/42 , A61K31/4985 , C07D487/04
Abstract: The present invention relates to pharmaceutically acceptable acid addition salts of sitagliptin, in particular anti-oxidant acid addition salts of sitagliptin and a process for its preparation. The present invention also provides a pharmaceutical composition using the pharmaceutically acceptable acid addition salts of sitagliptin.
Abstract translation: 本发明涉及西格列汀的药学上可接受的酸加成盐，特别是西格列汀的抗氧化酸加成盐及其制备方法。 本发明还提供了使用西格列汀的药学上可接受的酸加成盐的药物组合物。
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