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公开(公告)号：US20210214771A1
公开(公告)日：2021-07-15
申请号：US17151657
申请日：2021-01-18
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Mingsong CHEN , Kuan Moon BOO , Tiong Han TOH , Mauro AGUANNO , Soo Yong LAU , Huei YEO , Wei Fuh TEO
Abstract: An instrument for biological analysis includes a base, an excitation source, an optical sensor, an excitation optical system, and an emission optical system. The base is configured to receive a sample holder comprising a plurality of biological samples. The optical sensor is configured to receive emissions from the biological samples in response to the excitation source. The instrument may additionally include a sensor lens enclosed by a lens case and a focusing mechanism including a gear that engages the lens case, the focusing mechanism being accessible outside the enclosure for adjusting a focus. The may instrument further include a sensor aperture dispose along an emission optical path and a blocking structure disposed to cooperate with the sensor aperture such that none of the reflected radiation from an illuminated surface near the sample holder is received by the optical sensor that does not also reflect off another surface of the instrument.
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公开(公告)号：US20160230210A1
公开(公告)日：2016-08-11
申请号：US15017488
申请日：2016-02-05
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Mingsong CHEN , Kuan Moon BOO , Tiong Han TOH , Mauro AGUANNO , Soo Yong LAU , Huei Steven YEO , Wei Fuh TEO
CPC classification number: C12Q1/686 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0829 , B01L2300/168 , B01L2300/18 , G01N21/6428 , G01N21/6452 , G01N21/6456 , G01N21/6458 , G01N2021/6463 , G02B21/244
Abstract: An instrument for biological analysis includes a base, an excitation source, an optical sensor, an excitation optical system, and an emission optical system. The base is configured to receive a sample holder comprising a plurality of biological samples. The optical sensor is configured to receive emissions from the biological samples in response to the excitation source. The instrument may additionally include a sensor lens enclosed by a lens case and a focusing mechanism including a gear that engages the lens case, the focusing mechanism being accessible outside the enclosure for adjusting a focus. The may instrument further include a sensor aperture dispose along an emission optical path and a blocking structure disposed to cooperate with the sensor aperture such that none of the reflected radiation from an illuminated surface near the sample holder is received by the optical sensor that does not also reflect off another surface of the instrument.
Abstract translation: 用于生物分析的仪器包括基座，激发源，光学传感器，激发光学系统和发射光学系统。 基座被配置为接收包括多个生物样品的样品架。 光学传感器被配置为响应于激发源接收来自生物样品的发射。 该仪器还可以包括由透镜壳体包围的传感器透镜和包括与透镜壳体接合的齿轮的聚焦机构，聚焦机构可在外壳外部接近以调节焦点。 仪器还可以包括沿着发射光路设置的传感器孔径和设置成与传感器孔径配合的阻挡结构，使得来自样品保持器附近的被照射表面的反射的辐射没有被也不是的光学传感器接收 反射出仪器的另一个表面。
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Patent Agency Ranking
公开(公告)号：US20220011264A1
公开(公告)日：2022-01-13
申请号：US17305651
申请日：2021-07-12
Inventor： Marie MURAKAMI , Kyle BULLOCH , Neil OLSON , Ross WINNICK , Wei Fuh TEO , Michael THACKER
IPC: G01N27/447
Abstract: The present disclosure provides systems for gel electrophoresis and electrotransfer comprising one or more chambers that can removably and interchangeably receive either an electrophoresis cassette, or an electrotransfer cassette, and provides an electrical interface for both electrophoresis and electrotransfer of biomolecules. The present disclosure also provides electrophoresis devices including clamps and electrotransfer cassettes and related devices. Methods for electrophoresis and electrotransfer using the systems and devices of the disclosure are also provided.
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公开(公告)号：US20190126281A1
公开(公告)日：2019-05-02
申请号：US16116801
申请日：2018-08-29
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Yong CHU , Jeffrey MARKS , Jacob FREUDENTHAL , Mingsong CHEN , Tiong Han TOH , Mauro AGUANNO , Lik Seng LAU , Lian Seng LOH , Kok Siong TEO , Zeng Wei CHU , Xin MATHERS , Michael UY , Huei Steven YEO , Kuan Moon BOO , Way Xuang LEE , Chin Yong KOO , Wei Fuh TEO , Soo Yong LAU , Hon Siu SHIN , Zeqi TAN , Thomas WESSEL , David WOO
IPC: B01L7/00 , G01N21/27 , G01N21/64 , C12Q1/6806 , G01N35/02
Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.
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公开(公告)号：US20250155404A1
公开(公告)日：2025-05-15
申请号：US19028055
申请日：2025-01-17
Inventor： Marie MURAKAMI , Kyle BULLOCH , Neil OLSON , Ross WINNICK , Wei Fuh TEO , Michael THACKER
IPC: G01N27/447
Abstract: The present disclosure provides systems for gel electrophoresis and electrotransfer comprising one or more chambers that can removably and interchangeably receive either an electrophoresis cassette, or an electrotransfer cassette, and provides an electrical interface for both electrophoresis and electrotransfer of biomolecules. The present disclosure also provides electrophoresis devices including clamps and electrotransfer cassettes and related devices. Methods for electrophoresis and electrotransfer using the systems and devices of the disclosure are also provided.
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公开(公告)号：US20230273153A1
公开(公告)日：2023-08-31
申请号：US18112933
申请日：2023-02-22
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES HOLDINGS PTE LTD , PIERCE BIOTECHNOLOGY, INC. , THERMO FISHER ISRAEL LTD
Inventor： Chee Woei CHONG , Hwee Siong KUAH , Mio Xiu Lu LING , Kian Soon WONG , Jun Yao LIM , Jia Ni Beatrice LIM , Li Yong ONG , Xin Jie Jeryl CHENG , Kok Shyong CHONG , Zeqi TAN , Kguan Tyng LIM , Wei Fuh TEO , Quoc Cuong DINH , Tong BAO , Beng Heng LIM , Paul HANEY , Brian STEER , Michael THACKER , Boguslawa DWORECKI , Kelli FEATHER-HENIGAN , Xin MATHERS , Shahar SCHLEZINGER , Ronen BENARIEH
IPC: G01N27/447
CPC classification number: G01N27/44739 , G01N27/44708
Abstract: A protein transfer system includes at least one base configured to receive one or more consumable protein transfer stacks and at least one lid configured to cover the base. The lid(s) comprise(s) one or more electrodes for supplying current to the one or more consumable protein transfer stacks. The protein transfer system further includes at least one voltage source configured to supply the current to the one or more consumable protein transfer stacks, one or more processors, and one or more hardware storage devices storing instructions that are executable by the one or more processors to configure the protein transfer system to control operation of the one or more voltage sources.
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公开(公告)号：US20200241023A1
公开(公告)日：2020-07-30
申请号：US16777820
申请日：2020-01-30
Inventor： Kuan Moon BOO , Wei Fuh TEO , Zeqi TAN , Soo Yong LAU , Ming Tiong SIA , Woon Liang SOH , Ching Yee LAM , Shan Hua DONG , Marc HABERSTROH , Michael C. PALLAS , Hardeep Sangha
Abstract: A system for biological analysis includes a housing, a block assembly within the housing having a sample block and a baseplate, a heated cover and a cover carrier. The sample block receives a sample holder comprising an RFID tag. A first drive mechanism generates relative movement between the sample block and the baseplate along a first axis. A second drive mechanism generates relative movement between the heated cover and the cover carrier along a second axis that is different from the first axis. Based on a first command the first drive mechanism releasably engages the sample block and operates the second drive mechanism to releasably engage the heated cover with the cover carrier. The system also includes first and second RFID antennas that receive RFID data from the sample holder RFID tag that is read by at least one RFID reader.
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