公开(公告)号：US20190126281A1

公开(公告)日：2019-05-02

申请号：US16116801

申请日：2018-08-29

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Yong CHU ,  Jeffrey MARKS ,  Jacob FREUDENTHAL ,  Mingsong CHEN ,  Tiong Han TOH ,  Mauro AGUANNO ,  Lik Seng LAU ,  Lian Seng LOH ,  Kok Siong TEO ,  Zeng Wei CHU ,  Xin MATHERS ,  Michael UY ,  Huei Steven YEO ,  Kuan Moon BOO ,  Way Xuang LEE ,  Chin Yong KOO ,  Wei Fuh TEO ,  Soo Yong LAU ,  Hon Siu SHIN ,  Zeqi TAN ,  Thomas WESSEL ,  David WOO

IPC: B01L7/00 ,  G01N21/27 ,  G01N21/64 ,  C12Q1/6806 ,  G01N35/02

Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.

公开(公告)号：US20240416335A1

公开(公告)日：2024-12-19

申请号：US18739087

申请日：2024-06-10

Applicant: Life Technologies Holdings PTE Limited ,  Life Technologies Corporation

Inventor： Wui Khen Kevin LIAW ,  Kuan Moon Boo ,  Huei Steven YEO ,  Wern Yuh FOO ,  Joshua Mathew MEAD ,  Justina Linkai BONG ,  Mikko MAKINEN ,  Mio Xiu Lu LING ,  Way Xuang LEE ,  Wen Lun CHAN ,  Yunxiang LIU

IPC: B01L3/02

Abstract: Multichannel pipettes, electroporation systems utilizing the multichannel pipettes and methods for electroporating a cell. The electroporation system includes a multichannel pipette, a pipette tip(s), a pipette docking assembly, and a pulse generator. The pipette docking assembly includes a pipette station, a pipette station guard, and a reservoir.

公开(公告)号：US20240150699A1

公开(公告)日：2024-05-09

申请号：US18468504

申请日：2023-09-15

Applicant: LIFE TECHNOLOGIES HOLDINGS PTE LIMITED ,  LIFE TECHNOLOGIES CORPORATION

Inventor： Han WEI ,  Chee Wai CHAN ,  Wui Khen LIAW ,  Shan Hua DONG ,  See Chen GOH ,  Huei Steven YEO ,  Harmon Cosme SICAT, JR. ,  Mio Xiu Lu LING ,  Josh M. MEAD ,  Mikko MAKINEN ,  Beng Heng LIM ,  Kuan Moon BOO ,  Justina Linkai BONG ,  Chye Sin NG ,  Wee Liam LIM ,  Li Yang LIM ,  Way Xuang LEE

IPC: C12M1/42 ,  B01L3/02

CPC classification number: C12M35/02 ,  B01L3/0217 ,  B01L3/0275 ,  B01L2200/025 ,  B01L2200/0647 ,  B01L2300/0645 ,  B01L2300/12

Abstract: An electroporation system including one or more of a pipette, a pipette tip, a pipette docking assembly, and a pulse generator. The pipette docking assembly includes a pipette station, a pipette station guard, and a reservoir (e.g., a buffer tube). A method for transfecting a cell with a payload including providing an electroporation system, providing the cell, providing the payload, introducing the cell and the payload into a pipette tip, and electroporating the cell within the pipette tip by operating the electroporation system.

公开(公告)号：US20160230210A1

公开(公告)日：2016-08-11

申请号：US15017488

申请日：2016-02-05

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Mingsong CHEN ,  Kuan Moon BOO ,  Tiong Han TOH ,  Mauro AGUANNO ,  Soo Yong LAU ,  Huei Steven YEO ,  Wei Fuh TEO

IPC: C12Q1/68 ,  B01L7/00 ,  G01N21/64

CPC classification number: C12Q1/686 ,  B01L7/52 ,  B01L2200/10 ,  B01L2300/0654 ,  B01L2300/0829 ,  B01L2300/168 ,  B01L2300/18 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/6458 ,  G01N2021/6463 ,  G02B21/244

Abstract: An instrument for biological analysis includes a base, an excitation source, an optical sensor, an excitation optical system, and an emission optical system. The base is configured to receive a sample holder comprising a plurality of biological samples. The optical sensor is configured to receive emissions from the biological samples in response to the excitation source. The instrument may additionally include a sensor lens enclosed by a lens case and a focusing mechanism including a gear that engages the lens case, the focusing mechanism being accessible outside the enclosure for adjusting a focus. The may instrument further include a sensor aperture dispose along an emission optical path and a blocking structure disposed to cooperate with the sensor aperture such that none of the reflected radiation from an illuminated surface near the sample holder is received by the optical sensor that does not also reflect off another surface of the instrument.

Abstract translation: 用于生物分析的仪器包括基座，激发源，光学传感器，激发光学系统和发射光学系统。 基座被配置为接收包括多个生物样品的样品架。 光学传感器被配置为响应于激发源接收来自生物样品的发射。 该仪器还可以包括由透镜壳体包围的传感器透镜和包括与透镜壳体接合的齿轮的聚焦机构，聚焦机构可在外壳外部接近以调节焦点。 仪器还可以包括沿着发射光路设置的传感器孔径和设置成与传感器孔径配合的阻挡结构，使得来自样品保持器附近的被照射表面的反射的辐射没有被也不是的光学传感器接收 反射出仪器的另一个表面。