Abstract:
Prostanoic acid derivatives having the formula ##STR1## wherein A represents ethylene group or cis-vinylene group, R.sup.1 and R.sup.2 may be the same or different and each represents hydrogen atom or an alkyl group having 1-3 carbon atoms, R.sup.3 and R.sup.4 may be the same or different and each represents an alkyl group having 1-3 carbon atoms and R.sup.5 represents hydrogen atom or hydroxyl group and the pharmaceutically acceptable salts thereof and a process for the preparation thereof.The compounds are useful as anti-ulcerogenic or bronchodilating agents and may be prepared by oxidizing 9.xi.-hydroxy-15.xi.-protected-hydroxy-20-alkylideneprost-13(trans)-enoic acid derivatives.
Abstract:
Prostacyclin derivatives of formula (I): ##STR1## (wherein R.sup.1 represents a hydrogen atom or a lower alkyl group; R.sup.2 represents an alkenyl group having from 8 to 12 carbon atoms; and n represents an integer of from 1 to 8, inclusive) and pharmaceutically acceptable salts thereof, are valuable pharmaceuticals, showing excellent thrombocyte agglutination inhibitory, coronary blood vessel dilatory and bronchodilatory effects, and may be prepared by introducing the .dbd.CH(CH.sub.2).sub.n COOR.sup.1 side chain onto an appropriate compound by means of a Wittig reaction.
Abstract:
Carbacyclin derivatives with anti-ulcer activity comprise compounds of the general formula (I): ##STR1## (wherein R.sup.1 is selected from the group consisting of a hydrogen atom and an alkyl group having from 1 to 10 carbon atoms; R.sup.2 is selected from the group consisting of a hydrogen atom and a methyl group; and R.sup.3 is selected from the group consisting of a 3-butenyl group, a 4-pentenyl group and a 5-methyl-4-hexenyl group), and pharmaceutically acceptable salts thereof.
Abstract translation:具有抗溃疡活性的卡巴环素衍生物包括通式(I)的化合物:其中R 1选自氢原子和具有1至10个碳原子的烷基; R 2是 选自氢原子和甲基; R3选自3-丁烯基,4-戊烯基和5-甲基-4-己烯基)和药学上可接受的盐 其中。
Abstract:
Compounds of formula (I): ##STR1## have valuable platelet-aggregation inhibitory activities and may be used for the prophylaxis and treatment of such diseases as thrombosis.
Abstract:
Compounds of formula (Ic): ##STR1## having valuable platelet-aggregation inhibitory activities useful for the prophylaxis and treatment of such diseases as thrombosis and pharmaceutical compositions containing said compounds.
Abstract:
A solid electrolytic capacitor is obtained in which a sintered metal serves as an anode and a silver layer serves as a cathode. A surface of sintered metal made of tantalum or the like and having an open porosity ratio of more than 75% is oxidized so that an oxide film made of tantalum pentoxide or the like is deposited thereon. Cavities of the metal are filled with an electrically conductive material. Then, the metal is wound around a lead wire and made into a desired shape and size. The silver layer is formed on this porous metal body. Because a specific surface area of the sintered metal is large, a large capacity is obtained.
Abstract:
A solid electrolytic capacitor having a lowered leakage current characteristic and an improved ESR characteristic; which has been implemented by decreasing the defects contained in the dielectric film of the anode body. It includes a valve metal foil which makes anode and a sintered layer provided on the upper and lower surfaces of the valve metal foil, which sintered layer covering the entire surface of side faces of valve metal foil in three directions with exception of the anode lead portion. A flat plane area of valve metal foil, which makes anode, covered with sintered layer is not less than one half of the flat plane area of sintered layer.
Abstract:
A manufacturing system has an inspection data collecting apparatus that is capable of carrying out, upon receipt of a signal containing measurement data in different formats according to the type of inspection or a measuring instrument, processing in accordance with the signal and the format of data to create data in a certain format, and of transmitting a signal for giving an instruction to the measuring instrument in association with the format compatible with the measuring instrument. All data obtained by the inspections in all steps for manufacturing a product is accumulated as inspection data and exchanged among the steps.
Abstract:
The present invention provides a lens inspection apparatus and an inspection sheet that make is possible to easily evaluate the resolution of a lens at low cost. A lens inspection apparatus can include an inspection sheet having a test pattern, a sliding holding portion for holding the inspection sheet, a light source for introducing a light beam into the test pattern of the inspection sheet held by the sliding holding portion, a rotary holding portion for holding the sliding holding portion so that the sliding holding portion can rotate in a plane, and a measuring section for capturing an image projected on a screen through the inspection sheet and a projection lens to be inspected, and subjecting the image to image processing. The test pattern has a measuring region in which linear light-shielding portions are arranged in stripes so as to achieve a predetermined spatial frequency. By rotating the rotary holding portion, the resolution of the test pattern, in which the light-shielding portions extend in different directions, can be easily evaluated. Accordingly, the invention makes it possible to simply evaluate the lens resolution at a low cost.
Abstract:
Compounds of formula (I): ##STR1## (in which: R.sup.1 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or a heterocyclic-substituted alkyl group; R.sup.2 is an aryl-substituted alkyl group, a heterocyclic-substituted alkyl group or a diarylamino group; R.sup.3 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or an alkenyl group having from 3 to 6 carbon atoms; and each of the bonds represented by .alpha.-.beta. and .gamma.-.delta. is a carbon-carbon single bond or a carbon-carbon double bond;) and pharmaceutically acceptable salts and esters thereof are useful for the treatment and prophylaxis of prostatic hypertrophy. We also provide processes for their preparation.