公开(公告)号：US09427137B2

公开(公告)日：2016-08-30

申请号：US14891147

申请日：2014-05-15

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Shankar Mosur Venkatesan ,  Pallavi Vajinepalli ,  Vipin Gupta ,  Sushanth Govinahallisathyanarayana ,  Mandar Shirikant Kulkarni

IPC: H04N1/04 ,  A61B1/00 ,  G06T7/00 ,  A61B1/06 ,  A61B1/04 ,  A61B1/303 ,  A61B1/313 ,  A61B3/12 ,  H04N5/225 ,  H04N7/18

CPC classification number: A61B1/00006 ,  A61B1/04 ,  A61B1/0607 ,  A61B1/0661 ,  A61B1/303 ,  A61B1/3132 ,  A61B3/12 ,  G06T7/586 ,  G06T2207/10021 ,  G06T2207/10068 ,  G06T2207/10152 ,  G06T2207/30004 ,  H04N5/2256 ,  H04N7/183 ,  H04N2005/2255

Abstract: A system (100) is provided for imaging a patient's interior. The system comprises an imaging sensor (120) for acquiring a series of images of a region of interest (020) in the patient's interior, and a plurality of light sources (140) for illuminating the region of interest in the patient's interior from different light source directions (152-156). A light controller (160) is provided for controlling individual ones (142-146) of the plurality of light sources (140) to dynamically vary the light source directions (152-156) during said acquiring. Moreover, a processor (180) is provided for obtaining lighting data (164) indicative of the dynamically varying light source directions. The processor (180) is further arranged for using the lighting data to apply a photometric stereo technique to the image data so as to establish a three-dimensional [3D] surface profile of the region of interest. The processor (180) is further provided to detect insufficiently illuminated areas of the region of interest (020-024) in the images acquired by the imaging sensor (120), using the 3D surface profile of the region of interest. Accordingly, the system is enabled to establish a 3D surface profile of the region of interest from a series of images in a convenient and cost-effective manner.

Abstract translation: 提供了一种用于对患者内部进行成像的系统（100）。 该系统包括用于获取患者内部的感兴趣区域（020）的一系列图像的成像传感器（120）和用于从不同的光照射患者内部的感兴趣区域的多个光源（140） 来源方向（152-156）。 提供光控制器（160），用于控制多个光源（140）中的单个（142-146）在所述获取期间动态地改变光源方向（152-156）。 此外，提供处理器（180）以获得指示动态变化的光源方向的照明数据（164）。 处理器（180）还被布置为使用照明数据将光度立体声技术应用于图像数据，以便建立感兴趣区域的三维[3D]表面轮廓。 进一步提供处理器（180）以使用感兴趣区域的3D表面轮廓来检测由成像传感器（120）获取的图像中感兴趣区域（020-024）的未充分照明的区域。 因此，该系统能够以便利且具有成本效益的方式从一系列图像建立感兴趣区域的3D表面轮廓。

公开(公告)号：US10178971B2

公开(公告)日：2019-01-15

申请号：US14784961

申请日：2014-04-10

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Lu Wang ,  Subhendu Seth ,  Pallavi Vajinepalli ,  Vipin Gupta ,  Payal Keswarpu ,  Sarif Kumar Naik

IPC: A61B5/00 ,  A61B1/00 ,  A61B1/303 ,  A61B1/04

Abstract: The invention provides a system (100) for acquiring cervical images which comprises an image acquisition subsystem (120) for acquiring cervical images (122) of a cervical region of a patient during a colposcopy procedure, and a display subsystem (160) for displaying the cervical images on a display (060) by providing image data (162) of the cervical images to the display. According to the invention, the image acquisition subsystem (120) is arranged for, when operating in an interval mode, acquiring the cervical images (122) at predetermined time intervals to obtain a time-series of cervical images showing changes in the cervical region over time, and reporting a progress of said acquiring to the display subsystem. Moreover, the display subsystem (160) is arranged for establishing a progress indicator (400-416) on the display by generating indicator data (164) and providing the indicator data to the display (060), the progress indicator providing visual feedback on the progress of said acquiring to a user. Accordingly, the user is provided with visual feedback on a status of the acquiring of the cervical images. In particular, the progress indicator avoids that the user experiences a loss of control or confusion.

公开(公告)号：US10716613B2

公开(公告)日：2020-07-21

申请号：US14377184

申请日：2013-02-08

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Manfred Mueller ,  Payal Keswarpu ,  Vipin Gupta ,  Celine Firtion

IPC: A61B18/14 ,  A61B5/00 ,  A61B1/04 ,  A61B90/00 ,  A61B1/06 ,  A61B1/07 ,  A61B1/00 ,  A61B17/00 ,  A61B18/00

Abstract: The invention relates to a photonic probe apparatus and a method for probing tissue to detect and mark biological tissue with cancerous or precancerous states. The apparatus involves a probe for illuminating tissue and collecting light from an illuminated tissue region through the probe, a unit for analyzing collected light to determine whether a threshold measure of probability of a cancerous or precancerous lesion in the probed tissue region in contact with the probe is exceeded, and an integrated tissue marking facility which can be activated to mark the probed tissue region through the probe when the threshold measure is exceeded. The photonic probe apparatus and the method are especially suitable for probing regions in squamous and columnar epithelia to detect and mark regions with cervical cancer or cervical intraepithelial neoplasia (CIN).