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公开(公告)号：US20190209872A1
公开(公告)日：2019-07-11
申请号：US16326258
申请日：2017-08-17
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Robert Michael STARUCH , Shyam BHARAT , Shriram SETHURAMAN , Vijay PARTHASARATHY , Ajay ANAND , Ehsan DEHGHAN MARVAST
CPC classification number: A61N7/02 , A61B5/0036 , A61B5/015 , A61B5/055 , A61B5/4836 , A61B5/4848 , A61B8/483 , A61B8/485 , A61B8/5261 , A61B90/04 , A61B2017/00084 , A61B2017/00106 , A61B2017/00123 , A61B2017/00128 , A61B2018/00791 , A61B2018/00898 , A61B2034/101 , A61B2090/0472 , A61B2090/374 , A61B2090/378 , A61B2560/0276 , A61N2007/0039 , A61N2007/0052 , G01R33/4804 , G01R33/4814 , G01S7/52036 , G01S7/52042 , G01S15/8993
Abstract: A system (100) includes an imaging system (130), and a therapy control device (122). The imaging system (130) generates temperature maps (140) and strain maps (142) of localized tissues of a patient. The therapy control device (122) includes one or more computer processors configured to detect at least one failure mode (300, 302, 304, 400) of generated mild hyperthermia in the localized tissues of the patient according to at least one of the temperature maps, the strain maps, or a signal indicative of detected inertial cavitation. In some embodiments, the therapy control device either halts therapy or issues a warning.
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Patent Agency Ranking
公开(公告)号：US20160346031A1
公开(公告)日：2016-12-01
申请号：US15116965
申请日：2015-02-03
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Ajay ANAND , SHRIRAM SETHURAMAN , SHENG-WEN HUANG , Junbo LI
CPC classification number: A61B18/14 , A61B18/1492 , A61B18/1815 , A61B2018/00577 , A61B2018/00642 , A61B2018/00648 , A61B2018/00714 , A61B2018/00791 , A61B2018/00845 , A61B2018/00994 , A61N7/02
Abstract: The invention relates to a heat sink parameter determination apparatus for determining a parameter of a heat sink like a blood vessel within an object such as a person (3) by minimizing a deviation between a measured temperature distribution, which has preferentially been measured by ultrasound thermometry, and a modeled temperature distribution, wherein the modeled temperature distribution is modeled based on a provided heat source parameter like the location of an ablation needle (2) and the heat sink parameter to be determined by using a given thermal model. This determination of heat sink parameters, which may be geometric and/or flow parameters, considers the real temperature distribution and is thus based on real heat sink influences on the temperature distribution. This can lead to an improved determination of heat sink parameters and hence to a more accurate temperature distribution which may be determined based on the determined heat sink parameters.
Abstract translation: 本发明涉及一种散热器参数确定设备，用于通过将测量的温度分布（其优先通过超声波测温法测量）之间的偏差最小化来确定诸如人（3）的物体内的血管的参数， 以及建模的温度分布，其中基于所提供的热源参数（例如消融针（2）的位置）和通过使用给定的热模型来确定的散热器参数来建模所建模的温度分布。 散热参数的这种确定可以是几何和/或流量参数，因此考虑到实际的温度分布，因此基于实际的散热器对温度分布的影响。 这可以导致散热器参数的改进的确定，从而可以基于所确定的散热器参数来确定更准确的温度分布。
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公开(公告)号：US20200261059A1
公开(公告)日：2020-08-20
申请号：US16061455
申请日：2016-12-20
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Minnan XU , Balasundar Iyyavu RAJU , Ajay ANAND
Abstract: A Doppler ultrasound instrument (10) includes ultrasound pulse control and data acquisition electronics (12, 24, 26) for acquiring Doppler ultrasound data, an N-channel connector port (14) for simultaneously operatively connecting up to N ultrasound transducer patches (16) where N is an integer equal to or greater than two, and an electronic processor (30) programmed to concurrently determine up to N blood flow velocities corresponding to up to N patches operatively connected to the N channel connector port. The blood flow velocity for each patch may be determined by: determining transducer blood flow velocities for ultrasound transducers (60) of a transducer array of the patch; and determining the blood flow velocity for the patch as a highest determined transducer blood flow velocity or as an aggregation of highest determined transducer blood flow velocities.
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公开(公告)号：US20180304100A1
公开(公告)日：2018-10-25
申请号：US15769078
申请日：2016-10-13
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Shyam BHARAT , Ajay ANAND , Robert Michael STARUCH , Shriram SETHURAMAN , Vijay PARTHASARATHY , Ehsan DEHGHAN MARVAST
CPC classification number: A61N5/1048 , A61N5/1031 , A61N5/1037 , A61N5/1038 , A61N5/1039 , A61N7/02 , A61N2005/1087
Abstract: A method includes generating a hyperthermia heat plan for tissue of interest, generating a hyperthermia adapted radiation therapy plan for the tissue of interest, controlling a heat source (126) to deliver heat to the tissue of interest according to the hyperthermia heat plan, and controlling a radiation source of a radiation therapy system (100) to deliver radiation to the tissue of interest according to the hyperthermia adapted radiation therapy plan. A system includes a radiation treatment planner (124) configured to generate a hyperthermia adapted radiation therapy plan for the tissue of interest, a radiation therapy system (100) configured to deliver radiation in accordance with the hyperthermia adapted radiation therapy plan, and a hyperthermia heat delivery system (126) configured to deliver heat in accordance with a hyperthermia plan.
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公开(公告)号：US20180168552A1
公开(公告)日：2018-06-21
申请号：US15562202
申请日：2016-03-31
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： William SHI , Ajay ANAND , Sheng-Wen HUANG , Shriram SETHURAMAN , Hua XIE
CPC classification number: A61B8/485 , A61B8/085 , A61B8/5223 , A61B8/587 , A61B18/12 , A61B18/1477 , A61B2017/00106 , A61B2018/00577 , A61B2018/0212 , A61B2018/1869 , A61N7/02 , A61N2007/0052
Abstract: A medium of interest is interrogated according to ultrasound elastography imaging. A preliminary elasticity-spatial-map is formed. This map is calibrated against a reference elasticity-spatial-map that comprises an array (232) of different (240) elasticity values. The reference map is formed to be reflective of ultrasonic shear wave imaging of a reference medium. The reference medium is not, nor located at, the medium of interest, and may be homogeneous. Shear waves that are propagating in a medium are tracked by interrogating the medium. From tracking locations on opposite sides of an ablated-tissue border, propagation delay of a shear wave in the medium and of another shear wave are measured. The two shear waves result from respectively different pushes (128) that are separately issued. A processor decides, based on a function of the two delays, that the border crosses between the two locations. The calibrated map is dynamically updated and may include post-ablation border expansion (346) and time-annotated previous stages (344, 348).
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公开(公告)号：US20170360407A1
公开(公告)日：2017-12-21
申请号：US15540792
申请日：2015-12-17
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Shriram SETHURAMAN , Ajay ANAND , William Tao SHI
Abstract: An apparatus for deriving tissue temperature from thermal strain includes a thermal strain measuring module. The module uses ultrasound (156, 158) to measure thermal strain in a region, within a subject, that surrounds a location (166a, 166f) where a temperature sensor is disposed. Also included is a temperature measurement module configured for, via the sensor, measuring a temperature at the sensor while the sensor is inside the subject. Further included is a patient-specific thermal-strain-to-temperature-change proportionality calibration module. The calibration module is configured for calibrating (S238) a coefficient and for doing so based on a measurement of a temperature parameter at that location derived from output of the temperature measurement module and on a measurement of thermal strain at that location obtained via the strain measuring module. The coefficient is usable, in conjunction with a thermal strain measurement derived from another location within the region, in evaluating (S242), for that other location, another temperature parameter.
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