Gilvocarcin gene cluster, recombinant production and use thereof
    2.
    发明授权
    Gilvocarcin gene cluster, recombinant production and use thereof 失效
    Gilvocarcin基因簇,重组生产和使用

    公开(公告)号:US07799904B2

    公开(公告)日:2010-09-21

    申请号:US10866089

    申请日:2004-06-14

    CPC分类号: C12N15/52

    摘要: A nucleic acid molecule encoding the gilvocarcin V gene cluster and subunits thereof. Recombinant vectors and host cells comprising a nucleic acid compound encoding the gilvocarcin V gene cluster or subunits thereof. Host cells comprising recombinant vectors encoding the gilvocarcin polyketide synthase and gilvocarcin post-PKS modifying enzymes from Streptomyces griseoflavus can be used to produce gilvocarcin and functional gilvocarcin mutants, analogs and derivatives thereof with application as antibiotics, anticancer agents, immunosuppressants, antivirals, and neuroprotective agents.

    摘要翻译: 编码gvvocarcin V基因簇的核酸分子及其亚单位。 重组载体和宿主细胞,其包含编码gvvocarcin V基因簇或其亚基的核酸化合物。 包含重组载体的宿主细胞可以使用来自灰黄链霉菌(Streptomyces grisoflavus)的编码戈非卡因聚酮化合物合成酶和gilvocarcin后PKS修饰酶的重组载体,其用作抗生素,抗癌剂,免疫抑制剂,抗病毒剂和神经保护剂,可用于产生gilvocarcin和功能性gilvocarcin突变体,其类似物和衍生物 。

    Gilvocarcin gene cluster, recombinant production and use thereof
    5.
    发明申请
    Gilvocarcin gene cluster, recombinant production and use thereof 失效
    Gilvocarcin基因簇,重组生产和使用

    公开(公告)号:US20050048536A1

    公开(公告)日:2005-03-03

    申请号:US10866089

    申请日:2004-06-14

    CPC分类号: C12N15/52

    摘要: A nucleic acid molecule encoding the gilvocarcin V gene cluster and subunits thereof. Recombinant vectors and host cells comprising a nucleic acid compound encoding the gilvocarcin V gene cluster or subunits thereof. Host cells comprising recombinant vectors encoding the gilvocarcin polyketide synthase and gilvocarcin post-PKS modifying enzymes from Streptomyces griseoflavus can be used to produce gilvocarcin and functional gilvocarcin mutants, analogs and derivatives thereof with application as antibiotics, anticancer agents, immunosuppressants, antivirals, and neuroprotective agents.

    摘要翻译: 编码gvvocarcin V基因簇的核酸分子及其亚单位。 重组载体和宿主细胞,其包含编码gvvocarcin V基因簇或其亚基的核酸化合物。 包含重组载体的宿主细胞可以使用来自灰黄链霉菌(Streptomyces grisoflavus)的编码戈非卡因聚酮化合物合成酶和gilvocarcin后PKS修饰酶的重组载体,其用作抗生素,抗癌剂,免疫抑制剂,抗病毒剂和神经保护剂,可用于产生gilvocarcin和功能性gilvocarcin突变体,其类似物和衍生物 。

    Microprocessor-driven laser ceilometers
    7.
    发明授权
    Microprocessor-driven laser ceilometers 失效
    微处理器驱动的激光测距仪

    公开(公告)号:US4511249A

    公开(公告)日:1985-04-16

    申请号:US543782

    申请日:1983-10-20

    CPC分类号: G01S17/95 G01S17/10

    摘要: An improvement to a laser ceilometer and like instruments comprises a laser diode array which includes a plurality of laser diodes, and an array driver driving the laser diode array in accordance with commands from a microprocessor. The laser diodes are GaAs diodes. By utilizing the improvement, service life and reliability of the ceilometer are both increased.

    摘要翻译: 激光雷达测量仪和类似仪器的改进包括包括多个激光二极管的激光二极管阵列和根据来自微处理器的命令驱动激光二极管阵列的阵列驱动器。 激光二极管是GaAs二极管。 通过利用改进,ceilometer的使用寿命和可靠性都有所增加。