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公开(公告)号：US11236155B2
公开(公告)日：2022-02-01
申请号：US16829029
申请日：2020-03-25
Applicant: Janssen Pharmaceutica NV
Inventor： Bianca Van Broeck , Marc Mercken , Wilson Edwards , Sanjaya Singh , Jinquan Luo , Sherry La Porte , Rajkumar Ganesan , Chichi Huang
IPC: C07K16/18 , A61K39/00 , A61P25/28 , A61K39/395
Abstract: The invention provides antibodies or antigen binding fragments thereof that bind to 3pE Aβ and methods of making and using the antibodies or antigen binding fragments thereof, including use for formulations, administration and kits. The antibody and antigen binding fragments thereof and methods disclosed are useful for diagnosis, prognosis and treatment of Alzheimer's disease or other β-amyloid-related diseases.
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公开(公告)号：US10787495B2
公开(公告)日：2020-09-29
申请号：US16542751
申请日：2019-08-16
Applicant: Janssen Pharmaceutica NV
Inventor： Mark Macielag , Raymond J. Patch , Rui Zhang , Martin A. Case , Shamina M. Rangwala , James N. Leonard , Raul C. Camacho , Michael J. Hunter , Katharine E. D'Aquino , Wilson Edwards , Ronald V. Swanson , Wenying Jian , Yue-Mei Zhang , Mark J. Wall , Ellen Chi
IPC: A61K47/00 , A61K47/60 , C07K16/00 , A61K39/00 , A61K39/395 , A61K38/12 , A61K38/26 , C07K14/575 , A61K47/68 , C07K16/24 , A61K9/00 , A61K38/17 , C07K1/06 , C07K1/107 , A61K47/64 , A61P3/10 , A61K49/00 , C07K1/12 , C07K1/18 , C07K5/02 , A61P3/08 , A61P3/00 , A61P3/04 , A61P3/06 , A61K38/22 , A61K45/06 , A61K38/00
Abstract: The present invention relates to a monoclonal antibody platform designed to be coupled to therapeutic peptides to increase the half-life of the therapeutic peptide in a subject. The invention also relates to pharmaceutical compositions and methods for use thereof.
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公开(公告)号：US20220106387A1
公开(公告)日：2022-04-07
申请号：US17554461
申请日：2021-12-17
Applicant: Janssen Pharmaceutica NV
Inventor： Bianca Van Broeck , Marc Mercken , Wilson Edwards , Sanjaya Singh , Jinquan Luo , Sherry La Porte , Rajkumar Ganesan , Chichi Huang
IPC: C07K16/18
Abstract: The invention provides antibodies or antigen binding fragments thereof that bind to 3pE Aβ and methods of making and using the antibodies or antigen binding fragments thereof, including use for formulations, administration and kits. The antibody and antigen binding fragments thereof and methods disclosed are useful for diagnosis, prognosis and treatment of Alzheimer's disease or other β-amyloid-related diseases.
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公开(公告)号：US10858413B2
公开(公告)日：2020-12-08
申请号：US16344263
申请日：2017-10-26
Applicant: Janssen Pharmaceutica NV
Inventor： Mark Macielag , Raymond J. Patch , Rui Zhang , Martin A. Case , Mark J. Wall , Yue-Mei Zhang , Shamina M. Rangwala , James N. Leonard , Raul C. Camacho , Michael J. Hunter , Katharine E. D'Aquino , Wilson Edwards , Ronald V. Swanson , Wenying Jian , Ellen Chi
IPC: C07K14/575 , A61K47/68 , A61K38/17 , A61K38/26 , C07K1/06 , C07K1/107 , A61K47/64 , A61P3/10 , A61P3/08 , A61P3/00 , A61P3/04 , A61P3/06 , A61K38/22 , C07K16/24 , A61K9/00 , A61K49/00 , C07K1/12 , C07K1/18 , C07K5/02 , A61K47/60 , A61K45/06 , C07K16/00 , A61K38/00 , A61K39/00
Abstract: The present invention relates to a monoclonal antibody platform designed to be coupled to therapeutic peptides to increase the half-life of the therapeutic peptide in a subject. The invention also relates to pharmaceutical compositions and methods for use thereof.
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公开(公告)号：US10428134B2
公开(公告)日：2019-10-01
申请号：US15794250
申请日：2017-10-26
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： Mark Macielag , Raymond J Patch , Rui Zhang , Martin A Case , Shamina M Rangwala , James N Leonard , Raul C Camacho , Michael J Hunter , Katharine E. D'Aquino , Wilson Edwards , Ronald V Swanson , Wenying Jian , Yue-Mei Zhang , Mark Wall , Ellen Chi
IPC: C07K16/00 , A61K47/68 , A61K47/60 , C07K14/575 , A61K47/64 , A61P3/10 , A61K38/17 , A61K49/00 , C07K1/12 , C07K1/18 , C07K5/02 , A61P3/08 , A61P3/00 , A61P3/04 , A61P3/06 , A61K38/22 , A61K45/06 , C07K16/24 , A61K38/00 , A61K39/00
Abstract: The present invention relates to a monoclonal antibody platform designed to be coupled to therapeutic peptides to increase the half-life of the therapeutic peptide in a subject. The invention also relates to pharmaceutical compositions and methods for use thereof.
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Patent Agency Ranking
公开(公告)号：US12134636B2
公开(公告)日：2024-11-05
申请号：US17085128
申请日：2020-10-30
Applicant: Janssen Pharmaceutica NV
Inventor： Mark Macielag , Raymond J. Patch , Rui Zhang , Martin A. Case , Mark J. Wall , Yue-Mei Zhang , Shamina M. Rangwala , James N. Leonard , Raul C. Camacho , Michael J. Hunter , Katharine E. D'Aquino , Wilson Edwards , Ronald V. Swanson , Wenying Jian , Ellen Chi
IPC: A61K39/395 , A61K9/00 , A61K38/17 , A61K38/22 , A61K38/26 , A61K45/06 , A61K47/60 , A61K47/64 , A61K47/68 , A61K49/00 , A61P3/00 , A61P3/04 , A61P3/06 , A61P3/08 , A61P3/10 , C07K1/06 , C07K1/107 , C07K1/12 , C07K1/18 , C07K5/02 , C07K14/575 , C07K16/00 , C07K16/24 , A61K38/00 , A61K39/00
Abstract: The present invention relates to a monoclonal antibody platform designed to be coupled to therapeutic peptides to increase the half-life of the therapeutic peptide in a subject. The invention also relates to pharmaceutical compositions and methods for use thereof.
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公开(公告)号：US11767354B2
公开(公告)日：2023-09-26
申请号：US17168503
申请日：2021-02-05
Applicant: Janssen Pharmaceutica NV
Inventor： Mark Macielag , Raymond J. Patch , Rui Zhang , Martin A. Case , Shamina M. Rangwala , James N. Leonard , Raul C. Camacho , Michael J. Hunter , Katharine E. D'Aquino , Wilson Edwards , Ronald V. Swanson , Wenying Jian , Yue-Mei Zhang , Mark J. Wall , Ellen Chi
IPC: C07K14/575 , A61K47/68 , C07K16/24 , A61K9/00 , A61K38/17 , A61K38/26 , C07K1/06 , C07K1/107 , A61K47/64 , A61P3/10 , A61K49/00 , C07K1/12 , C07K1/18 , C07K5/02 , A61K47/60 , A61P3/08 , A61P3/00 , A61P3/04 , A61P3/06 , A61K38/22 , A61K45/06 , C07K16/00 , A61K38/00 , A61K39/00
CPC classification number: C07K14/575 , A61K9/0019 , A61K38/17 , A61K38/1709 , A61K38/22 , A61K38/26 , A61K45/06 , A61K47/60 , A61K47/64 , A61K47/68 , A61K47/6811 , A61K47/6845 , A61K47/6883 , A61K49/0032 , A61K49/0052 , A61K49/0056 , A61P3/00 , A61P3/04 , A61P3/06 , A61P3/08 , A61P3/10 , C07K1/061 , C07K1/1072 , C07K1/12 , C07K1/18 , C07K5/0205 , C07K14/57545 , C07K16/00 , C07K16/24 , A61K38/00 , A61K2039/505 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/92 , C07K2317/94 , C07K2319/30
Abstract: The present invention comprises conjugates comprising a monoclonal antibody conjugated to a cyclic PYY peptide. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel conjugates are useful for preventing, treating or ameliorating diseases and disorders disclosed herein.
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公开(公告)号：US10968265B2
公开(公告)日：2021-04-06
申请号：US16344174
申请日：2017-10-26
Applicant: Janssen Pharmaceutica NV
Inventor： Mark Macielag , Raymond J. Patch , Rui Zhang , Martin A. Case , Shamina M. Rangwala , James N. Leonard , Raul C. Camacho , Michael J. Hunter , Katharine E. D'Aquino , Wilson Edwards , Ronald V. Swanson , Wenying Jian , Yue-Mei Zhang , Mark J. Wall , Ellen Chi
IPC: C07K14/575 , A61K47/68 , C07K16/24 , A61K9/00 , A61K38/17 , A61K38/26 , C07K1/06 , C07K1/107 , A61K47/64 , A61P3/10 , A61K49/00 , C07K1/12 , C07K1/18 , C07K5/02 , A61K47/60 , A61P3/08 , A61P3/00 , A61P3/04 , A61P3/06 , A61K38/22 , A61K45/06 , C07K16/00 , A61K38/00 , A61K39/00
Abstract: The present invention comprises conjugates comprising a monoclonal antibody conjugated to a cyclic PYY peptide. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel conjugates are useful for preventing, treating or ameliorating diseases and disorders disclosed herein.
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公开(公告)号：US20180125998A1
公开(公告)日：2018-05-10
申请号：US15794250
申请日：2017-10-26
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： Mark Macielag , Raymond J. Patch , Rui Zhang , Martin A. Case , Shamina M. Rangwala , James N. Leonard , Raul C. Camacho , Michael J. Hunter , Katharine E. D'Aquino , Wilson Edwards , Ronald V. Swanson , Wenying Jian , Yue-Mei Zhang , Mark Wall , Ellen Chi
Abstract: The present invention relates to a monoclonal antibody platform designed to be coupled to therapeutic peptides to increase the half-life of the therapeutic peptide in a subject. The invention also relates to pharmaceutical compositions and methods for use thereof.
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10.发明授权公开(公告)号：US11591379B2
公开(公告)日：2023-02-28
申请号：US16820174
申请日：2020-03-16
Applicant: Janssen Pharmaceutica NV
Inventor： Mark Macielag , Raymond J. Patch , Rui Zhang , Martin A. Case , Shamina M. Rangwala , James N. Leonard , Raul C. Camacho , Michael J. Hunter , Katharine E. D'Aquino , Wilson Edwards , Ronald V. Swanson , Wenying Jian , Yue-Mei Zhang , Mark J. Wall , Ellen Chi
IPC: C07K14/575 , A61K47/68 , C07K16/24 , A61K38/17 , A61K38/26 , A61K47/64 , A61P3/10 , A61K47/60 , A61P3/08 , A61P3/04 , A61P3/06 , A61K38/22 , A61K9/00 , C07K1/06 , C07K1/107 , A61K49/00 , C07K1/12 , C07K1/18 , C07K5/02 , A61P3/00 , A61K45/06 , C07K16/00 , A61K38/00 , A61K39/00
Abstract: The present invention comprises conjugates comprising a monoclonal antibody conjugated to a cyclic PYY peptide. The invention also relates to pharmaceutical compositions and methods for use thereof. The novel conjugates are useful for preventing, treating or ameliorating diseases and disorders disclosed herein.
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