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    RESIZABLE VALVE BASE FOR CARDIOVASCULAR VALVE ASSEMBLY
    1.
    发明申请
    RESIZABLE VALVE BASE FOR CARDIOVASCULAR VALVE ASSEMBLY 审中-公开
    用于心脏瓣膜组件的可固定阀座

    公开(公告)号：US20130274872A1

    公开(公告)日：2013-10-17

    申请号：US13995559

    申请日：2012-01-05

    Applicant: Ivan Vesely

    Inventor： Ivan Vesely

    IPC: A61F2/24

    CPC classification number: A61F2/2403 ,  A61F2/2412 ,  A61F2250/001 ,  A61F2250/006 ,  F04C2270/0421

    Abstract: A resizable valve base for a cardiovascular valve assembly that is comprised of the resizable valve base and a valve member that is detachably coupled thereto. The resizable valve base has adjustable dimensions to allow use with both small and large size valve members. The valve base comprises a frame comprised of a plurality of frame sections, and each frame section includes a mounting portion and a pair of arcuate portions extending from opposite sides of the mounting portion. The valve base also includes a plurality of joining elements for joining together the frame sections to define a generally cylindrical opening having a diameter, wherein said plurality of joining elements allow adjacent frame sections to move towards or away from each other in order to modify the diameter of the opening, thereby moving the valve base between a collapsed position and an expanded position.

    Abstract translation: 用于心血管瓣膜组件的可调整大小的阀座，其由可调节尺寸的阀座和可拆卸地联接到其上的阀构件组成。 可调节尺寸的阀座具有可调节的尺寸，以允许与小尺寸和大尺寸阀构件一起使用。 阀座包括由多个框架部分构成的框架，并且每个框架部分包括安装部分和从安装部分的相对侧延伸的一对弓形部分。 阀座还包括多个连接元件，用于将框架部分接合在一起以限定具有直径的大致圆柱形开口，其中所述多个接合元件允许相邻的框架部分朝彼此移动或远离彼此移动，以便改变直径 从而使阀座在折叠位置和展开位置之间移动。

    BIOREACTOR FOR ENGINEERED TISSUE
    5.
    发明申请
    BIOREACTOR FOR ENGINEERED TISSUE 有权
    工程组织生物反应器

    公开(公告)号：US20120288911A1

    公开(公告)日：2012-11-15

    申请号：US13394471

    申请日：2011-05-12

    Applicant: Marvi A. Matos ,  William B. Carlson ,  Ivan Vesely ,  Yansong Gu

    Inventor： Marvi A. Matos ,  William B. Carlson ,  Ivan Vesely ,  Yansong Gu

    IPC: C12N11/00 ,  B01J19/18

    CPC classification number: C12M25/16 ,  C12M21/08 ,  C12M33/00

    Abstract: A system for generating a tissue construct includes a mixing chamber, a piston chamber, a reaction chamber, and a pump. The mixing chamber is configured to receive a hydrogel solution and a cell suspension solution. The piston chamber includes a first piston and is configured to receive a mixture of the hydrogel solution and the cell suspension solution from the mixing chamber. The first piston is configured to push the mixture through one or more capillaries into the reaction chamber. The reaction is configured to receive the mixture and a cross-linking initiator. The pump is configured to move the mixture through the reaction chamber such that the mixture and the cross-linking initiator combine to form an encapsulated cell material.

    Abstract translation: 用于产生组织结构的系统包括混合室，活塞室，反应室和泵。 混合室构造成接收水凝胶溶液和细胞悬液。 活塞室包括第一活塞并且构造成从混合室接收水凝胶溶液和细胞悬浮液的混合物。 第一活塞构造成将混合物推动通过一个或多个毛细管进入反应室。 该反应被配置为接收混合物和交联引发剂。 泵被配置为使混合物移动通过反应室，使得混合物和交联引发剂结合形成封装的细胞材料。

    Bioprosthetic cardiovascular valve system
    6.
    发明授权
    Bioprosthetic cardiovascular valve system 有权
    生物假体心血管瓣系统

    公开(公告)号：US07776083B2

    公开(公告)日：2010-08-17

    申请号：US11319349

    申请日：2005-12-28

    Applicant: Ivan Vesely

    Inventor： Ivan Vesely

    IPC: A61F2/24 ,  A61F2/06 ,  A61M29/00

    CPC classification number: A61F2/2409 ,  A61B2017/2944 ,  A61B2090/3929 ,  A61B2090/397 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/243 ,  A61F2/2439 ,  A61F2220/0066

    Abstract: A cardiovascular valve system including a permanent base unit that is affixed to the patient using conventional sutures or staples, and a collapsible valve having a collapsible frame that mates with the permanent base unit, and supports valve leaflets. An installed collapsible frame may be re-collapsed and disengaged from the permanent housing. A new collapsible valve is then installed, to resume the function of the prosthesis.

    Abstract translation: 一种心血管瓣系统，其包括使用常规缝合线或吻合钉固定在患者身上的永久基座单元，以及具有与永久性基座单元配合的可折叠框架的可折叠阀，并支撑瓣膜单元。 安装的可折叠框架可能被重新折叠并与永久外壳脱离。 然后安装新的可折叠阀，以恢复假体的功能。

    CARDIOVASCULAR VALVE ASSEMBLY WITH RESIZABLE DOCKING STATION
    8.
    发明申请
    CARDIOVASCULAR VALVE ASSEMBLY WITH RESIZABLE DOCKING STATION 审中-公开
    心脏瓣膜组装与可调节的锁定站

    公开(公告)号：US20080004696A1

    公开(公告)日：2008-01-03

    申请号：US11760840

    申请日：2007-06-11

    Applicant: Ivan Vesely

    Inventor： Ivan Vesely

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2230/0054 ,  A61F2250/001 ,  A61F2250/006 ,  A61F2250/0082

    Abstract: A cardiovascular valve assembly comprised of a base member and an exchangeable valve member detachably mountable thereto. The base member includes a tubular body. The valve member includes a valve frame that supports a plurality of valve leaflets. The diameter of the tubular body can be increased to receive an exchangeable valve member having larger dimensions.

    Abstract translation: 一种心血管阀组件，其包括可拆卸地安装到其上的基部构件和可更换阀构件。 基部构件包括管状体。 阀构件包括支撑多个瓣叶的阀框架。 可以增加管状体的直径以接收具有较大尺寸的可更换的阀构件。

    System for minimally invasive insertion of a bioprosthetic heart valve
    9.
    发明授权
    System for minimally invasive insertion of a bioprosthetic heart valve 失效
    用于微生物插入生物假体心脏瓣膜的系统

    公开(公告)号：US06569196B1

    公开(公告)日：2003-05-27

    申请号：US09597918

    申请日：2000-06-19

    Applicant: Ivan Vesely

    Inventor： Ivan Vesely

    IPC: A61F224

    CPC classification number: A61F2/2409 ,  A61B2017/2944 ,  A61F2/2412 ,  A61F2/243 ,  A61F2250/0059 ,  A61F2250/006

    Abstract: A system for minimally invasive insertion of a bioprosthetic heart valve. The system includes a collapsible tissue-based valve system, a catheter-based valve delivery system, a surgical platform and a device tracking and visualization system. The collapsible valve system includes: (i) a permanent outer frame (10) that is affixed to the patient using conventional sutures or staples, and (ii) a collapsible valve (20) having a collapsible inner frame (21) that mates with the outer frame (10), and supports valve leaflets (13). The inner frame (21) is moved to a collapsed position and located at the previously installed outer frame (10). The inner frame (21) is then expanded to lock the inner frame (21) to the outer frame (10). The inner frame (21) may be re-collapsed and disengaged from the outer frame (10). A new collapsible valve (20) is then installed, to resume the function of the prosthesis.

    Abstract translation: 用于微生物插入生物假体心脏瓣膜的系统。 该系统包括可折叠的基于组织的阀系统，基于导管的阀输送系统，手术平台和设备跟踪和可视化系统。 可折叠阀系统包括：（i）使用常规缝合线或吻合钉固定到患者的永久外框架（10），和（ii）具有可折叠内框架（21）的可折叠阀门（20），所述可折叠内框架（21） 外框架（10），并支撑阀传单（13）。 内框架（21）移动到折叠位置并且位于预先安装的外框架（10）处。 然后将内框架（21）膨胀以将内框架（21）锁定到外框架（10）。 内框架（21）可以与外框架（10）重新折叠并脱开。 然后安装新的可折叠阀（20），以恢复假体的功能。

    Three-dimensional tracking and imaging system
    10.
    发明授权
    Three-dimensional tracking and imaging system 失效
    三维跟踪和成像系统

    公开(公告)号：US6019725A

    公开(公告)日：2000-02-01

    申请号：US813662

    申请日：1997-03-07

    Applicant: Ivan Vesely ,  Wayne L. Smith

    Inventor： Ivan Vesely ,  Wayne L. Smith

    IPC: A61B17/34 ,  A61B5/06 ,  A61B8/00 ,  A61B8/08 ,  G01S7/521 ,  G01S15/89

    CPC classification number: A61B8/0841 ,  G01S15/8993 ,  G01S7/52087 ,  A61B5/06 ,  A61B8/0833 ,  G01S7/52079 ,  Y10S128/916

    Abstract: A 3-D tracking and imaging system (1600) for tracking the position of a surgical instrument (e.g., a catheter, probe, a sensor, needle or the like) inserted into a body, and displaying a 3-D image showing the position of the surgical instrument in reference to a 3-D image of the environment surrounding the surgical instrument. The 3-D tracking and imaging system (1600) aiding a physician in the guidance of the surgical instrument inside the body.

    Abstract translation: 一种用于跟踪插入到身体中的外科器械（例如，导管，探头，传感器，针等）的位置的3D跟踪和成像系统（1600），并且显示示出位置的3-D图像 参考手术器械周围环境的三维图像。 三维跟踪和成像系统（1600）帮助医师在身体内的手术器械的引导中。

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