公开(公告)号：US20240175075A1

公开(公告)日：2024-05-30

申请号：US18527656

申请日：2023-12-04

申请人： IntegenX Inc.

发明人： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey M. Smith ,  Philip Justus Wunderle ,  David King

IPC分类号： C12Q1/6806 ,  B01L3/00 ,  C12Q1/686 ,  G01N27/447

CPC分类号： C12Q1/6806 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  C12Q1/686 ,  G01N27/44743 ,  G01N27/44791 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/041 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/0848 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2400/0406 ,  B01L2400/0478

摘要： An instrument includes a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to close off a fluidic channel in the body. A cartridge interface is configured to engage the cartridge.

公开(公告)号：US11891650B2

公开(公告)日：2024-02-06

申请号：US17181228

申请日：2021-02-22

申请人： INTEGENX, INC.

发明人： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey M. Smith ,  Philip Justus Wunderle ,  David King

IPC分类号： C12Q1/6806 ,  B01L3/00 ,  C12Q1/686 ,  G01N27/447

CPC分类号： C12Q1/6806 ,  B01L3/50273 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502738 ,  C12Q1/686 ,  G01N27/44743 ,  G01N27/44791 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/041 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/087 ,  B01L2300/0848 ,  B01L2300/123 ,  B01L2400/0406 ,  B01L2400/0478 ,  C12Q1/6806 ,  C12Q1/6846 ,  C12Q2565/629

摘要： Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.

公开(公告)号：US10961561B2

公开(公告)日：2021-03-30

申请号：US16250646

申请日：2019-01-17

申请人： IntegenX, Inc.

发明人： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey M. Smith ,  Philip Justus Wunderle ,  David King

IPC分类号： B01L3/00 ,  G01N1/10 ,  C12Q1/6806 ,  C12Q1/686 ,  G01N27/447

摘要： Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.

公开(公告)号：US20190256890A1

公开(公告)日：2019-08-22

申请号：US16250646

申请日：2019-01-17

申请人： IntegenX, Inc.

发明人： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey M. Smith ,  Philip Justus Wunderle ,  David King

IPC分类号： C12Q1/6806 ,  B01L3/00 ,  C12Q1/686 ,  G01N27/447

摘要： Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.

公开(公告)号：US10208332B2

公开(公告)日：2019-02-19

申请号：US15117053

申请日：2015-04-30

申请人： IntegenX Inc.

发明人： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey Smith ,  Philip Justus Wunderle ,  David King

IPC分类号： A61J1/06 ,  B01L3/00 ,  G01N21/00 ,  G01N15/06 ,  C12Q1/6806 ,  C12Q1/686 ,  G01N27/447

摘要： Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.

公开(公告)号：US20210180114A1

公开(公告)日：2021-06-17

申请号：US17181228

申请日：2021-02-22

申请人： INTEGENX, INC.

发明人： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey M. Smith ,  Philip Justus Wunderle ,  David King

IPC分类号： C12Q1/6806 ,  B01L3/00 ,  C12Q1/686 ,  G01N27/447

摘要： Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.

公开(公告)号：US20170002399A1

公开(公告)日：2017-01-05

申请号：US15117053

申请日：2015-04-30

申请人： INTEGENX INC.

发明人： David Eberhart ,  William D. Nielsen ,  Helen Franklin ,  Stevan B. Jovanovich ,  Dennis Lehto ,  Kaiwan Chear ,  David King ,  James Klevenberg ,  Chungsoo Charles Park ,  Corey Smith ,  Philip Justus Wunderle

IPC分类号： C12Q1/68 ,  G01N27/447 ,  B01L3/00

CPC分类号： C12Q1/6806 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/041 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/0848 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2400/0406 ,  B01L2400/0478 ,  C12Q1/686 ,  G01N27/44743 ,  G01N27/44791 ,  C12Q1/6846 ,  C12Q2565/629

摘要： Provided herein is a fluidic cartridge having a body comprising a malleable material and a layer comprising a deformable material bonded to a surface of the body that seals one or more fluidic channels that communicate with one or more valve bodies formed in a surface of the body. The valve can be closed by applying pressure to the deformable material sufficient to crush and close off a fluidic channel in the body. Also provided are a cartridge interface configured to engage the cartridge. Also provided is a system including a cartridge interface and methods of using the cartridge and system.

摘要翻译： 本文提供了一种流体盒，其具有包括可延展材料的主体和包含结合到主体表面的可变形材料的层，所述可变形材料密封与形成在主体表面中的一个或多个阀体连通的一个或多个流体通道。 可以通过向可变形材料施加足够的压力来关闭阀门，以压缩和关闭体内的流体通道。 还提供了构造成接合盒的盒接口。 还提供了包括盒式接口和使用盒和系统的方法的系统。