公开(公告)号：US11414370B2

公开(公告)日：2022-08-16

申请号：US16965426

申请日：2018-12-11

申请人： IOI OLEO GMBH

发明人： Dirk Lochmann ,  Sebastian Reyer ,  Michael Stehr

IPC分类号： C07C67/08 ,  B01J31/12 ,  C07C67/60

摘要： A process is described for the preparation of polyglycerol fatty acid esters from a reaction mixture to which a metallic catalyst is added, as well as to a method for the purification of an intermediate synthesis product which contains excess fatty acid in addition to polyglycerol fatty acid esters. Compared with the prior art, a significantly improved yield and a higher process speed is obtained along with more economic use of raw materials, auxiliary materials, solvents and energy.

公开(公告)号：US12121613B2

公开(公告)日：2024-10-22

申请号：US17277825

申请日：2019-07-01

申请人： IOI OLEO GMBH

发明人： Dirk Lochmann ,  Sebastian Reyer ,  Sharareh Salar Behzadi ,  Michael Stehr ,  Andreas Zimmer

IPC分类号： A61K9/20 ,  A61K8/02 ,  A61K8/37 ,  A61K9/00 ,  A61K9/16 ,  A61K31/155

CPC分类号： A61K9/2054 ,  A61K8/0245 ,  A61K8/375 ,  A61K9/0075 ,  A61K9/1617 ,  A61K9/1694 ,  A61K9/2013 ,  A61K9/2095 ,  A61K31/155

摘要： The invention relates to lipophilic transport particles for cosmetic or pharmaceutical active ingredients. The lipophilic transport particles comprise polyglycerol fatty acid ester as a main constituent and, because of the absence of polymorphic transformations, even during long storage, neither have volume changes nor allow the problem of expulsion of the adhering or enclosed active ingredient, due to intense structuring of the crystal lattice and associated compaction, to arise, and therefore the degree of loading with active ingredient and the release profile are stable.

公开(公告)号：US12030852B2

公开(公告)日：2024-07-09

申请号：US17378967

申请日：2019-01-23

申请人： IOI Oleo GmbH

发明人： Dirk Lochmann ,  Sebastian Reyer ,  Michael Stehr

IPC分类号： C07C67/02 ,  C07C67/03 ,  C07C67/08 ,  C07C69/675 ,  C07C69/732 ,  C12P7/62

CPC分类号： C07C69/675 ,  C07C67/02 ,  C07C67/03 ,  C07C67/08 ,  C07C69/732 ,  C12P7/62 ,  C12Y301/01

摘要： The invention relates to a method for producing fatty alcohol esters of 3-hydroxybutyric acid and their acylated derivatives, as well as the products thus obtained and their use.

公开(公告)号：US11492321B2

公开(公告)日：2022-11-08

申请号：US17378950

申请日：2019-01-23

申请人： IOI Oleo GmbH

发明人： Dirk Lochmann ,  Sebastian Reyer ,  Michael Stehr

IPC分类号： C07C67/10

摘要： The invention relates to a method for producing capped (blocked) 3-hydroxybutyric acids and their salts and esters, as well as the products obtainable in this way and their use.

公开(公告)号：US12091383B2

公开(公告)日：2024-09-17

申请号：US17378962

申请日：2019-01-23

申请人： IOI Oleo GmbH

发明人： Dirk Lochmann ,  Sebastian Reyer ,  Michael Stehr

IPC分类号： C07C69/675 ,  C07C67/08 ,  C12P7/62

CPC分类号： C07C69/675 ,  C07C67/08 ,  C12P7/62 ,  C07C67/08 ,  C07C69/675

摘要： The invention relates to a method for producing lipids comprising structural units based on glycerides of 3-hydroxybutyric and/or 3-alkoxybutyric acids as well as the products thus obtained and their use.

公开(公告)号：US20240294456A1

公开(公告)日：2024-09-05

申请号：US18645646

申请日：2024-04-25

申请人： IOI Oleo GmbH

发明人： Dirk Lochmann ,  Sebastian Reyer ,  Michael Stehr

IPC分类号： C07C69/675 ,  C07C67/02 ,  C07C67/03 ,  C07C67/08 ,  C07C69/732 ,  C12P7/62

CPC分类号： C07C69/675 ,  C07C67/02 ,  C07C67/03 ,  C07C67/08 ,  C07C69/732 ,  C12P7/62 ,  C12Y301/01

摘要： The invention relates to a method for producing fatty alcohol esters of 3-hydroxybutyric acid and their acylated derivatives, as well as the products thus obtained and their use.

公开(公告)号：US11919851B2

公开(公告)日：2024-03-05

申请号：US17379204

申请日：2019-01-23

申请人： IOI Oleo GmbH

发明人： Dirk Lochmann ,  Sebastian Reyer ,  Michael Stehr

IPC分类号： C07C67/08 ,  A23L33/10 ,  A61K31/22 ,  C07C69/675

CPC分类号： C07C69/675 ,  A23L33/10 ,  A61K31/22 ,  C07C67/08

摘要： The invention relates to a method for producing polyol esters, especially polyglycerol esters, of optionally acylated 3-hydroxybutyric acid, as well as the products thus obtained and their use.