公开(公告)号：US12031176B2

公开(公告)日：2024-07-09

申请号：US16940517

申请日：2020-07-28

Applicant: HITACHI HIGH-TECH CORPORATION

Inventor： Masataka Shirai ,  Tomoyuki Sakai ,  Kenko Uchida

IPC: C12Q1/68 ,  C12N15/10 ,  C12Q1/6806 ,  C12Q1/6809 ,  C12Q1/6837 ,  C40B40/08 ,  C40B50/06 ,  G01N33/543

CPC classification number: C12Q1/6837 ,  C12N15/1003 ,  C12N15/1093 ,  C12N15/1096 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/6809 ,  C40B40/08 ,  C40B50/06 ,  G01N33/54306

Abstract: The purpose of the present invention is to provide a single cell analysis device in which the improvement of the nucleic acid capturing efficiency and the improvement of the cell capturing efficiency are both achieved and a highly accurate single cell analysis data is thereby obtained. The present invention relates to an improvement of a cell analysis device including a two-dimensional array chip having a plurality of cell capture parts capable of capturing a single cell in each of the capture parts, and nucleic acid capture parts corresponding to the respective cell capture parts, the nucleic acid capture parts being capable of capturing a nucleic acid extracted from the cell captured by the cell capture part.

公开(公告)号：US11733205B2

公开(公告)日：2023-08-22

申请号：US17253805

申请日：2018-06-22

Applicant: HITACHI HIGH-TECH CORPORATION

Inventor： Satoshi Takahashi ,  Ryoji Inaba ,  Takashi Anazawa ,  Tomoyuki Sakai ,  Yusuke Goto

IPC: G01N27/453 ,  G01N27/447 ,  G01N30/74 ,  G01N21/64

CPC classification number: G01N27/44756 ,  G01N27/44721 ,  G01N30/74 ,  G01N2021/6463

Abstract: The present invention aims to provide an electrophoresis apparatus which makes it possible to execute protein analysis with a high throughput. The electrophoresis apparatus according to the present invention is equipped with a capillary array which is configured by arraying a plurality of capillaries, a measurement light irradiation unit which irradiates with measurement light, a first lens array which includes a plurality of first lenses which are arrayed in correspondence with the plurality of capillaries, a second lens array which includes a plurality of second lenses which are arrayed in correspondence with the plurality of capillaries, and a light receiving unit which receives light which is incident upon the capillaries via the first lens array from the measurement light irradiation unit via the second lens array.

公开(公告)号：US12092607B2

公开(公告)日：2024-09-17

申请号：US18341078

申请日：2023-06-26

Applicant: Hitachi High-Tech Corporation

Inventor： Satoshi Takahashi ,  Ryoji Inaba ,  Takashi Anazawa ,  Tomoyuki Sakai ,  Yusuke Goto

IPC: G01N27/447 ,  G01N21/64 ,  G01N30/74

CPC classification number: G01N27/44756 ,  G01N27/44721 ,  G01N2021/6463 ,  G01N27/44791 ,  G01N30/74

Abstract: The present invention aims to provide an electrophoresis apparatus which makes it possible to execute protein analysis with a high throughput. The electrophoresis apparatus according to the present invention is equipped with a capillary array which is configured by arraying a plurality of capillaries, a measurement light irradiation unit which irradiates with measurement light, a first lens array which includes a plurality of first lenses which are arrayed in correspondence with the plurality of capillaries, a second lens array which includes a plurality of second lenses which are arrayed in correspondence with the plurality of capillaries, and a light receiving unit which receives light which is incident upon the capillaries via the first lens array from the measurement light irradiation unit via the second lens array.