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公开(公告)号:US20220152014A1
公开(公告)日:2022-05-19
申请号:US17508267
申请日:2021-10-22
Applicant: Gilead Sciences, Inc.
Inventor: Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC: A61K31/47 , A61K31/352 , A61K31/4709 , A61K31/497 , A61K31/501 , A61K31/513 , A61K31/5377 , A61K31/541 , C07D215/14 , C07D311/58 , C07D401/10 , C07D403/10 , C07D405/10 , C07D413/12 , C07D413/14 , C07D417/10 , C07D471/04 , C07D519/00
Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号:US20200163953A1
公开(公告)日:2020-05-28
申请号:US16667572
申请日:2019-10-29
Applicant: Gilead Sciences, Inc.
Inventor: Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC: A61K31/47 , A61K31/541 , C07D215/14 , C07D413/12 , A61K31/5377 , A61K31/513 , C07D401/10 , A61K31/4709 , C07D417/10 , C07D403/10 , A61K31/497 , A61K31/501 , C07D405/10 , C07D413/14 , C07D471/04 , C07D519/00 , C07D311/58 , A61K31/352
Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号:US20230041518A1
公开(公告)日:2023-02-09
申请号:US17379175
申请日:2021-07-19
Applicant: Gilead Sciences, Inc.
Inventor: Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC: A61K31/47 , A61K31/4375 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04
Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号:US11116760B2
公开(公告)日:2021-09-14
申请号:US16667306
申请日:2019-10-29
Applicant: Gilead Sciences, Inc.
Inventor: Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC: C07D413/14 , A61K31/5377 , A61K31/47 , A61K31/4375 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号:US20220226337A1
公开(公告)日:2022-07-21
申请号:US17550591
申请日:2021-12-14
Applicant: Gilead Sciences, Inc.
Inventor: Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC: A61K31/5377 , A61K31/343 , A61K31/353 , A61K31/357 , A61K31/416 , A61K31/4375 , A61K31/4709 , A61K31/513 , A61K31/519 , A61K31/538 , A61K31/541 , A61K45/06 , C07D295/00 , C07D307/87 , C07D319/18 , C07D405/10 , C07D407/10 , C07D413/14 , C07D471/04
Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号:US20200155563A1
公开(公告)日:2020-05-21
申请号:US16667373
申请日:2019-10-29
Applicant: Gilead Sciences, Inc.
Inventor: Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC: A61K31/5377 , A61K31/541 , A61K45/06 , C07D405/10 , A61K31/4709 , A61K31/357 , C07D319/18 , C07D413/14 , A61K31/513 , C07D307/87 , A61K31/343 , C07D295/00 , A61K31/538 , C07D407/10 , A61K31/353 , A61K31/416 , C07D471/04 , A61K31/4375 , A61K31/519
Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号:US20200155538A1
公开(公告)日:2020-05-21
申请号:US16667306
申请日:2019-10-29
Applicant: Gilead Sciences, Inc.
Inventor: Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC: A61K31/47 , A61K45/06 , C07D215/14 , C07D401/10 , A61K31/4709 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D401/14 , C07D407/14 , A61K31/506 , A61K31/501 , A61K31/5355 , C07D413/12 , C07D417/12 , A61K31/541 , A61K31/517 , A61K31/4375 , C07D471/04 , C07D487/04 , A61K31/519
Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号:US20250032473A1
公开(公告)日:2025-01-30
申请号:US18740078
申请日:2024-06-11
Applicant: Gilead Sciences, Inc.
Inventor: Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC: A61K31/47 , A61K31/4375 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D215/18 , C07D401/04 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D475/02 , C07D487/04 , C07D491/04 , C07D491/06 , C07D491/08 , C07D498/10 , C07D513/04
Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号:US12053462B2
公开(公告)日:2024-08-06
申请号:US17379175
申请日:2021-07-19
Applicant: Gilead Sciences, Inc.
Inventor: Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC: C07D215/02 , A61K31/4375 , A61K31/47 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D215/18 , C07D401/04 , C07D413/04 , C07D417/14 , C07D475/02 , C07D491/04 , C07D491/06 , C07D491/08 , C07D498/10 , C07D513/04
CPC classification number: A61K31/47 , A61K31/4375 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D215/18 , C07D401/04 , C07D413/04 , C07D417/14 , C07D475/02 , C07D491/04 , C07D491/06 , C07D491/08 , C07D498/10 , C07D513/04
Abstract: The present disclosure provides a compound of Formula (I):
or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.-
公开(公告)号:US11174256B2
公开(公告)日:2021-11-16
申请号:US16667532
申请日:2019-10-29
Applicant: Gilead Sciences, Inc.
Inventor: Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC: C07D471/04 , A61K31/437 , A61K31/541
Abstract: The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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