公开(公告)号：US09498778B2

公开(公告)日：2016-11-22

申请号：US14538565

申请日：2014-11-11

申请人： GENMARK DIAGNOSTICS, INC.

发明人： Scott Corey ,  Brian Murphy ,  Eric Schneider ,  David Walter Wright ,  Dominic Aiello ,  Andrew Fish ,  Jay Srinivasan ,  George Maltezos

IPC分类号： B01L7/00 ,  B01L3/00

CPC分类号： B01L7/52 ,  B01L3/502715 ,  B01L3/502723 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/502761 ,  B01L3/502792 ,  B01L3/505 ,  B01L2200/027 ,  B01L2200/0668 ,  B01L2200/0673 ,  B01L2200/0684 ,  B01L2200/10 ,  B01L2200/14 ,  B01L2300/021 ,  B01L2300/022 ,  B01L2300/0609 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0663 ,  B01L2300/0681 ,  B01L2300/0809 ,  B01L2300/0858 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/123 ,  B01L2300/18 ,  B01L2300/1805 ,  B01L2300/1827 ,  B01L2400/0427 ,  B01L2400/043 ,  B01L2400/0481 ,  B01L2400/0487 ,  C12Q1/6846 ,  C12Q2563/113 ,  C12Q2563/143 ,  C12Q2563/159 ,  C12Q2565/629

摘要： In one embodiment, a multiplex fluid processing cartridge includes a sample well, a deformable fluid chamber, a mixing well with a mixer disposed therein, a lysis chamber including a lysis mixer, an electrowetting grid for microdroplet manipulation, and electrosensor arrays configured to detect analytes of interest. An instrument for processing the cartridge is configured to receive the cartridge and to selectively apply thermal energy, magnetic force, and electrical connections to one or more discrete locations on the cartridge and is further configured to compress the deformable chamber(s) in a specified sequence.

摘要翻译： 在一个实施例中，多重流体处理盒包括样品阱，可变形流体室，与其中设置的混合器的混合井，包括裂解混合器的裂解室，用于微滴操作的电润湿栅格，以及配置成检测分析物的电传感器阵列 出于兴趣。 用于处理盒的装置被配置为接收盒并且选择性地将热能，磁力和电连接施加到盒上的一个或多个离散位置，并且还被配置成以指定的顺序压缩可变形室 。

公开(公告)号：US20210060566A1

公开(公告)日：2021-03-04

申请号：US17095142

申请日：2020-11-11

申请人： GenMark Diagnostics, Inc.

发明人： Scott Corey ,  Brian Murphy ,  Eric Schneider ,  David Walter Wright ,  Dominic Aiello ,  Andrew Fish ,  Jay Srinivasan ,  George Maltezos

IPC分类号： B01L7/00 ,  B01L3/00 ,  C12Q1/6844 ,  C12Q1/6806

摘要： In one embodiment, a multiplex fluid processing cartridge includes a sample well, a deformable fluid chamber, a mixing well with a mixer disposed therein, a lysis chamber including a lysis mixer, an electrowetting grid for microdroplet manipulation, and electrosensor arrays configured to detect analytes of interest. An instrument for processing the cartridge is configured to receive the cartridge and to selectively apply thermal energy, magnetic force, and electrical connections to one or more discrete locations on the cartridge and is further configured to compress the deformable chamber(s) in a specified sequence.

公开(公告)号：US20200156065A1

公开(公告)日：2020-05-21

申请号：US16541893

申请日：2019-08-15

申请人： GenMark Diagnostics, Inc.

发明人： Scott Corey ,  Brian Murphy ,  Eric Schneider ,  David Walter Wright ,  Dominic Aiello ,  Andrew Fish ,  Jay Srinivasan ,  George Maltezos

IPC分类号： B01L3/00 ,  C12Q1/6806

摘要： In one embodiment, a multiplex fluid processing cartridge includes a sample well, a deformable fluid chamber, a mixing well with a mixer disposed therein, a lysis chamber including a lysis mixer, an electrowetting grid for microdroplet manipulation, and electrosensor arrays configured to detect analytes of interest. An instrument for processing the cartridge is configured to receive the cartridge and to selectively apply thermal energy, magnetic force, and electrical connections to one or more discrete locations on the cartridge and is further configured to compress the deformable chamber(s) in a specified sequence.