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公开(公告)号：US20170320962A1
公开(公告)日：2017-11-09
申请号：US15491378
申请日：2017-04-19
Applicant: GENMAB A/S
Inventor： Joost J. NEIJSSEN , Bart DE GOEIJ , Edward Norbert VAN DEN BRINK , Aran Frank LABRIJN , Rene HOET , Janine SCHUURMAN , Paul PARREN , Jan VAN DE WINKEL
IPC: C07K16/30 , A61K45/06 , C07K16/40 , A61K39/395 , G01N33/574 , C07K16/28 , A61K39/00
Abstract: Isolated monoclonal antibodies which bind to human c-Met, the hepatocyte growth factor receptor, and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and therapeutic and diagnostic methods for using the antibodies are also disclosed.
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公开(公告)号：US20170233497A1
公开(公告)日：2017-08-17
申请号：US15414122
申请日：2017-01-24
Applicant: GENMAB A/S
Inventor： Aran Frank LABRIJN , Joyce I. MEESTERS , Ewald T. J. VAN DEN BREMER , Joost J. NEIJSSEN , Patrick VAN BERKEL , Bart DE GOEIJ , Tom VINK , Jan VAN DE WINKEL , Janine SCHUURMAN , Paul PARREN
CPC classification number: C07K16/468 , A61K2039/505 , C07K16/1063 , C07K16/2809 , C07K16/2863 , C07K16/2887 , C07K16/32 , C07K16/40 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/526 , C07K2317/53 , C07K2317/55 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/6854
Abstract: Novel heterodimeric antibody-Fc-containing proteins, such as bispecific antibodies, and novel methods for producing such proteins
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公开(公告)号：US20240317861A1
公开(公告)日：2024-09-26
申请号：US18539509
申请日：2023-12-14
Applicant: GENMAB A/S
Inventor： Isil ALTINTAS , David SATIJN , Edward VAN DEN BRINK , Dennis VERZIJL , Rik RADEMAKER , Paul PARREN , Bart DE GOEIJ
IPC: C07K16/28 , A61K39/395 , A61K45/06 , A61P35/00 , C07K16/42
CPC classification number: C07K16/2827 , A61K39/3955 , A61K45/06 , A61P35/00 , C07K16/2809 , C07K16/4258 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/35 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/732 , C07K2317/76 , C07K2317/92
Abstract: The present invention relates to novel antibodies and their use in medicine. In particular, the invention relates to bispecific antibodies capable of binding human PD-L1 and capable of binding human CD3. Novel classes of antibodies capable of binding human PD-L1 are also provided. The invention furthermore relates to uses of the antibodies of the invention and to methods, nucleic acid constructs and host cells for producing antibodies of the invention.
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公开(公告)号：US20200270366A1
公开(公告)日：2020-08-27
申请号：US16667369
申请日：2019-10-29
Applicant: GENMAB A/S
Inventor： Joost J. NEIJSSEN , Joyce I. MEESTERS , Bart DE GOEIJ , Aran Frank LABRIJN , Paul PARREN , Janine SCHUURMAN
Abstract: Bispecific antibodies which comprise one antigen-binding region binding to an epitope of human epidermal growth factor receptor 2 (HER2) and one antigen-binding region binding to human CD3, and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and methods for preparing and using the antibodies are also disclosed.
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公开(公告)号：US20200079872A1
公开(公告)日：2020-03-12
申请号：US16548883
申请日：2019-08-23
Applicant: GENMAB A/S
Inventor： Joost J. NEIJSSEN , Bart DE GOEIJ , Edward Norbert VAN DEN BRINK , Aran Frank LABRIJN , Rene HOET , Janine SCHUURMAN , Paul PARREN , Jan VAN DE WINKEL
IPC: C07K16/30 , C07K16/40 , A61K45/06 , A61K39/395 , C07K16/28 , G01N33/574 , A61P35/00
Abstract: Isolated monoclonal antibodies which bind to human c-Met, the hepatocyte growth factor receptor, and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and therapeutic and diagnostic methods for using the antibodies are also disclosed.
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Patent Agency Ranking
公开(公告)号：US20180215827A1
公开(公告)日：2018-08-02
申请号：US15832337
申请日：2017-12-05
Applicant: GENMAB A/S
Inventor： Bart DE GOEIJ , Simone DE HAIJ , Thilo RIEDL , Rene HOET , Ole BAADSGAARD , Jan VAN DE WINKEL , David SATIJN , Paul PARREN , Aran Frank LABRIJN , Joyce MEESTERS , Janine SCHUURMAN , Edward N. VAN DEN BRINK
CPC classification number: C07K16/2863 , A61K2039/505 , C07K16/2809 , C07K16/32 , C07K2317/31 , C07K2317/52 , C07K2317/526 , C07K2317/528 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/77 , C07K2317/92
Abstract: Isolated monoclonal antibodies which bind to human epidermal growth factor receptor 2 (HER2), and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and therapeutic and diagnostic methods for using the antibodies are also disclosed.
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公开(公告)号：US20240209117A1
公开(公告)日：2024-06-27
申请号：US18507869
申请日：2023-11-13
Applicant: GENMAB A/S
Inventor： Aran Frank LABRIJN , Joyce I. MEESTERS , Edwald T. J. VAN DER BREMER , Joost J. NEIJSSEN , Patrick VAN BERKEL , Bart DE GOEIJ , Tom VINK , Jan VAN DE WINKEL , Janine SCHUURMAN , Paul PARREN
CPC classification number: C07K16/468 , C07K16/1063 , C07K16/2809 , C07K16/2863 , C07K16/2887 , C07K16/32 , C07K16/40 , G01N33/6854 , A61K2039/505 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/526 , C07K2317/53 , C07K2317/55 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94
Abstract: Novel heterodimeric antibody-Fc-containing proteins, such as bispecific antibodies, and novel methods for producing such proteins
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公开(公告)号：US20200262932A1
公开(公告)日：2020-08-20
申请号：US16777053
申请日：2020-01-30
Applicant: GENMAB A/S
Inventor： Aran Frank LABRIJN , Joyce I. MEESTERS , Ewald T. J. VAN DEN BREMER , Joost J. NEIJSSEN , Patrick VAN BERKEL , Bart DE GOEIJ , Tom VINK , Jan VAN DE WINKEL , Janine SCHUURMAN , Paul PARREN
Abstract: Novel heterodimeric antibody-Fc-containing proteins, such as bispecific antibodies, and novel methods for producing such proteins
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公开(公告)号：US20180194845A1
公开(公告)日：2018-07-12
申请号：US15832366
申请日：2017-12-05
Applicant: GENMAB A/S
Inventor： Bart DE GOEIJ , Simone DE HAIJ , Thilo RIEDL , Rene HOET , Ole BAADSGAARD , Jan VAN DE WINKEL , David SATIJN , Paul PARREN , Aran Frank LABRIJN , Joyce MEESTERS , Janine SCHUURMAN , Edward N. VAN DEN BRINK
CPC classification number: C07K16/2863 , A61K2039/505 , C07K16/2809 , C07K16/32 , C07K2317/31 , C07K2317/52 , C07K2317/526 , C07K2317/528 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/77 , C07K2317/92
Abstract: Isolated monoclonal antibodies which bind to human epidermal growth factor receptor 2 (HER2), and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and therapeutic and diagnostic methods for using the antibodies are also disclosed.
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公开(公告)号：US20180179286A1
公开(公告)日：2018-06-28
申请号：US15832421
申请日：2017-12-05
Applicant: GENMAB A/S
Inventor： Bart DE GOEIJ , Simone DE HAIJ , Thilo RIEDL , Rene HOET , Ole BAADSGAARD , Jan VAN DE WINKEL , David SATIJN , Paul PARREN , Aran Frank LABRIJN , Joyce MEESTERS , Janine SCHUURMAN , Edward N. VAN DEN BRINK
CPC classification number: C07K16/2863 , A61K2039/505 , C07K16/2809 , C07K16/32 , C07K2317/31 , C07K2317/52 , C07K2317/526 , C07K2317/528 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/77 , C07K2317/92
Abstract: Isolated monoclonal antibodies which bind to human epidermal growth factor receptor 2 (HER2), and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and therapeutic and diagnostic methods for using the antibodies are also disclosed.
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