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公开(公告)号：US20240368306A1
公开(公告)日：2024-11-07
申请号：US18439879
申请日：2024-02-13
Applicant: Genentech, Inc.
Inventor： Xiaocheng CHEN , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC: C07K16/40 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/10 , A61K47/18 , A61K47/22 , A61K47/26 , C07K16/24
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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公开(公告)号：US12098426B2
公开(公告)日：2024-09-24
申请号：US17553210
申请日：2021-12-16
Applicant: GENENTECH, INC.
Inventor： Michael Townsend , Alvernia Francesca Setiadi , Tracy Staton
IPC: A61K39/395 , C07K16/24 , C07K16/28 , C12Q1/6883 , G01N33/564 , A61K39/00
CPC classification number: C12Q1/6883 , A61K39/3955 , C07K16/244 , C07K16/2866 , G01N33/564 , A61K2039/505 , C07K2317/76 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158 , G01N2333/47 , G01N2333/522 , G01N2333/535 , G01N2333/5412 , G01N2333/5421 , G01N2333/8146 , G01N2800/285 , G01N2800/50 , G01N2800/52
Abstract: The present invention concerns markers of multiple sclerosis, their use, and treatment with IL-17 antagonists, including IL-17 antibodies, of subjects with increased levels of such markers.
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公开(公告)号：US20240410009A1
公开(公告)日：2024-12-12
申请号：US18815555
申请日：2024-08-26
Applicant: GENENTECH, INC.
Inventor： Michael Townsend , Alvernia Francesca Setiadi , Tracy Staton
IPC: C12Q1/6883 , A61K39/00 , A61K39/395 , C07K16/24 , C07K16/28 , G01N33/564
Abstract: The present invention concerns markers of multiple sclerosis, their use, and treatment with IL-17 antagonists, including IL-17 antibodies, of subjects with increased levels of such markers.
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公开(公告)号：US20220098668A1
公开(公告)日：2022-03-31
申请号：US17553210
申请日：2021-12-16
Applicant: GENENTECH, INC.
Inventor： Michael Townsend , Alvernia Francesca Setiadi , Tracy Staton
IPC: C12Q1/6883 , G01N33/564 , A61K39/395 , C07K16/28 , C07K16/24
Abstract: The present invention concerns markers of multiple sclerosis, their use, and treatment with IL-17 antagonists, including IL-17 antibodies, of subjects with increased levels of such markers.
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Patent Agency Ranking
公开(公告)号：US11939396B2
公开(公告)日：2024-03-26
申请号：US16916822
申请日：2020-06-30
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC: C07K16/40 , A61K39/395 , C07K16/24 , A61K39/00 , A61K45/06 , A61K47/10 , A61K47/18 , A61K47/22 , A61K47/26
CPC classification number: C07K16/40 , A61K39/3955 , A61K39/39591 , C07K16/244 , C12Y304/21059 , A61K2039/505 , A61K45/06 , A61K47/10 , A61K47/183 , A61K47/22 , A61K47/26 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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公开(公告)号：US10738131B2
公开(公告)日：2020-08-11
申请号：US15893238
申请日：2018-02-09
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC: C07K16/40 , A61K39/395 , A61K47/18 , A61K47/22 , A61K47/26 , A61K47/10 , A61K45/06 , C07K16/24 , A61K39/00
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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公开(公告)号：US11708608B2
公开(公告)日：2023-07-25
申请号：US15525460
申请日：2015-11-10
Applicant: Genentech, Inc.
Inventor： Rajita Khosla , Vladimir Ramirez-Carrozzi , Tracy Staton , Brian Yaspan , Joseph Arron , David Choy , Amy Dressen
IPC: C12Q1/68 , C12Q1/6883 , G01N33/68
CPC classification number: C12Q1/6883 , G01N33/6869 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172 , Y02A50/30
Abstract: The invention relates to methods of treating a patient suffering from an IL-33-mediated disorder, such as asthma, comprising administering to the patient an IL-33 axis binding antagonist based on the genotype of the /L1RL1gene, the genotype of a polymorphism in genomic vicinity to the IL-33 gene, the expression level of periostin or the expression level of soluble ST2. The invention further relates to methods of determining whether a patient is at increased risk of an IL-33-mediated disorder, as well as methods of determining whether a patient suffering from such a disorder is likely to respond to a treatment comprising an IL-33 axis binding antagonist, based on the genotype of the /L1RL1gene the genotype of a polymorphism in genomic vicinity to the IL-33 gene, the expression level of periostin or the expression level of soluble ST2.
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公开(公告)号：US11236391B2
公开(公告)日：2022-02-01
申请号：US15662079
申请日：2017-07-27
Applicant: Genentech, Inc.
Inventor： Michael Townsend , Alvernia Francesca Setiadi , Tracy Staton
IPC: A61K39/395 , C07K16/24 , C07K16/28 , C12Q1/6883 , G01N33/564 , A61K39/00
Abstract: The present invention concerns markers of multiple sclerosis, their use, and treatment with IL-17 antagonists, including IL-17 antibodies, of subjects with increased levels of such markers.
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公开(公告)号：US10752703B2
公开(公告)日：2020-08-25
申请号：US16544421
申请日：2019-08-19
Applicant: Genentech, Inc.
Inventor： Xiaocheng Chen , Mark Dennis , Janet Jackman , James T. Koerber , Mason Lu , Henry R. Maun , Kathila Rajapaksa , Saroja Ramanujan , Tracy Staton , Lawren Wu , Tangsheng Yi
IPC: C07K16/40 , A61K39/395 , A61K39/00 , A61K47/18 , A61K47/22 , A61K47/26 , A61K47/10 , A61K45/06 , C07K16/24
Abstract: The invention provides compositions including anti-tryptase antibodies and pharmaceutical compositions thereof, as well as methods of using the same.
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