公开(公告)号：US10449283B2

公开(公告)日：2019-10-22

申请号：US15498918

申请日：2017-04-27

申请人： Fenwal, Inc.

发明人： Christopher J. Wegener ,  Bret M. Olson ,  Alaina Schlinker ,  Steven Binninger ,  Avnie A. Kadakia ,  Kyle Thompson ,  Kyle Wolok ,  Melanie Hamilton

IPC分类号： A61M1/34 ,  A61M1/26 ,  C12M1/00 ,  C12M1/26 ,  C12M1/36 ,  G01N33/543 ,  A61M1/36

摘要： A cell processing system includes at least one processor connectable to a source container filled with a biological fluid, the at least one processor including a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet, one or more containers selectively connected to the first outlet; and, and a magnet. The system also includes a controller coupled to the at least one processor and configured to operate the spinning membrane to receive biological fluid from the source container and to direct the target cells to one of the one or more containers, to pause to permit magnetic particles to be associated with the target cells, and to operate the spinning membrane to receive the contents of one of the one or more containers with the magnet applied to the target cells associated with the magnetic particles.

公开(公告)号：US20200009309A1

公开(公告)日：2020-01-09

申请号：US16576484

申请日：2019-09-19

申请人： Fenwal, Inc.

发明人： Christopher J. Wegener ,  Bret M. Olson ,  Alaina Schlinker ,  Steven Binninger ,  Avnie A. Kadakia ,  Kyle Thompson ,  Kyle Wolok ,  Melanie Hamilton

IPC分类号： A61M1/26 ,  C12M1/00 ,  C12M1/26 ,  C12M1/36 ,  G01N33/543

摘要： A cell processing system includes at least one processor connectable to a source container filled with a biological fluid, the processor including a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet, first and second containers selectively connected to the first outlet; and a magnet. The system also includes a controller configured to operate the spinning membrane to receive biological fluid and to direct the target cells to the first container, to pause to permit magnetic particles to be associated with the target cells in the first container, to operate the spinning membrane to receive the contents of the first container with the magnet applied to the target cells associated with the magnetic particles, to remove or deactivate the magnet, and to transfer the target cells to the second container.

公开(公告)号：US11883575B2

公开(公告)日：2024-01-30

申请号：US16576484

申请日：2019-09-19

申请人： Fenwal, Inc.

发明人： Christopher J. Wegener ,  Bret M. Olson ,  Alaina Schlinker ,  Steven Binninger ,  Avnie A. Kadakia ,  Kyle Thompson ,  Kyle Wolok ,  Melanie Hamilton

IPC分类号： A61M1/26 ,  A61M1/36 ,  C12M1/00 ,  C12M1/26 ,  C12M1/36 ,  G01N33/543

CPC分类号： A61M1/262 ,  A61M1/265 ,  A61M1/362 ,  A61M1/3618 ,  C12M23/28 ,  C12M29/14 ,  C12M33/14 ,  C12M41/48 ,  C12M47/04 ,  G01N33/54326 ,  G01N33/54366

摘要： A cell processing system includes at least one processor connectable to a source container filled with a biological fluid, the processor including a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet, first and second containers selectively connected to the first outlet; and a magnet. The system also includes a controller configured to operate the spinning membrane to receive biological fluid and to direct the target cells to the first container, to pause to permit magnetic particles to be associated with the target cells in the first container, to operate the spinning membrane to receive the contents of the first container with the magnet applied to the target cells associated with the magnetic particles, to remove or deactivate the magnet, and to transfer the target cells to the second container.

公开(公告)号：US20170315121A1

公开(公告)日：2017-11-02

申请号：US15498918

申请日：2017-04-27

申请人： Fenwal, Inc.

发明人： Christopher J. Wegener ,  Bret M. Olson ,  Alaina Schlinker ,  Steven Binninger ,  Avnie A. Kadakia ,  Kyle Thompson ,  Kyle Wolok ,  Melanie Hamilton

IPC分类号： G01N33/569 ,  G01N33/543 ,  C12M1/36 ,  C12M1/00 ,  C12M1/26

摘要： A cell processing system includes at least one processor connectable to a source container filled with a biological fluid, the at least one processor including a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet, one or more containers selectively connected to the first outlet; and, and a magnet. The system also includes a controller coupled to the at least one processor and configured to operate the spinning membrane to receive biological fluid from the source container and to direct the target cells to one of the one or more containers, to pause to permit magnetic particles to be associated with the target cells, and to operate the spinning membrane to receive the contents of one of the one or more containers with the magnet applied to the target cells associated with the magnetic particles.