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公开(公告)号:US11318327B2
公开(公告)日:2022-05-03
申请号:US16665360
申请日:2019-10-28
申请人: Elekta, Inc.
摘要: The present disclosure relates to a method for use in adaptive radiotherapy and a treatment planning device. The method may comprise accessing a first medical image and a second medical image that represent a region of interest of a patient at different times. Each medical image is segmented into a target region and at least one non-target region. The method may further comprise accessing a deformation vector field including a plurality of vectors, wherein each vector defines a geometric transformation to map a respective voxel in the first medical image to a corresponding voxel in the second medical image. The method may further comprise generating a modified deformation vector field by: identifying a first vector in the deformation vector field that maps a voxel in the first medical image to a voxel that is in a non-target region in the second medical image; and determining whether the first vector causes a distance between the mapped voxel and the target region to increase and, if so, reducing the magnitude of the first vector. The method may further comprise post-processing the modified deformation vector field to compensate for changes in the shape or size of the target region.
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公开(公告)号:US10668300B2
公开(公告)日:2020-06-02
申请号:US15836474
申请日:2017-12-08
申请人: Elekta, Inc.
发明人: Sami Hissoiny , Michel Moreau
摘要: Radiation treatment planning and administration can include a Monte Carlo computer simulation tool to simulate photo-generated electrons in tissue. In the simulation, electrons that have left tissue voxels and entered air voxels can be evaluated to identify electrons that are circling along a spiraling trajectory in the air voxels. After at least one full spiraling circumference or other specified distance has been traversed using a detailed electron transport model, a simpler linear ballistic motion model can be instituted. This speeds simulation while accurately accounting for spiraling electrons that re-enter tissue voxels.
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公开(公告)号:US20190070436A1
公开(公告)日:2019-03-07
申请号:US15697667
申请日:2017-09-07
申请人: Elekta, Inc.
摘要: The present disclosure relates to a method for use in adaptive radiotherapy and a treatment planning device. The method may comprise accessing a first medical image and a second medical image that represent a region of interest of a patient at different times. Each medical image is segmented into a target region and at least one non-target region. The method may further comprise accessing a deformation vector field including a plurality of vectors, wherein each vector defines a geometric transformation to map a respective voxel in the first medical image to a corresponding voxel in the second medical image. The method may further comprise generating a modified deformation vector field by: identifying a first vector in the deformation vector field that maps a voxel in the first medical image to a voxel that is in a non-target region in the second medical image; and determining whether the first vector causes a distance between the mapped voxel and the target region to increase and, if so, reducing the magnitude of the first vector. The method may further comprise post-processing the modified deformation vector field to compensate for changes in the shape or size of the target region.
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公开(公告)号:US09974977B2
公开(公告)日:2018-05-22
申请号:US14924553
申请日:2015-10-27
申请人: Elekta, Inc.
IPC分类号: G01D18/00 , A61N5/10 , A61B5/055 , A61B6/03 , A61B8/08 , G06T7/33 , G06T7/11 , A61B90/00 , A61B34/20
CPC分类号: A61N5/1065 , A61B5/055 , A61B6/032 , A61B8/085 , A61B2034/2065 , A61B2090/367 , A61N5/1037 , A61N5/1038 , A61N5/1039 , A61N5/1049 , A61N2005/1055 , A61N2005/1058 , A61N2005/1061 , G06T7/11 , G06T7/337 , G06T2207/10081 , G06T2207/10088 , G06T2207/10132 , G06T2207/20021 , G06T2207/30096
摘要: An adaptive therapy delivery system can receive imaging information including a volumetric image comprising a target such as a tumor or one or more other structures, and can receive imaging information corresponding to one or more imaging slices comprising different portions of the target, such as imaging slices acquired at different times after acquisition of the volumetric image. The system can spatially register information from an earlier-acquired image with a portion of the target included in a later-acquired one of the imaging slices. The system can then determine an updated location of the target indicated by the spatially-registered information. Using the updated location, the system can generate an updated therapy protocol to control delivery of a therapy beam.
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公开(公告)号:US20230082049A1
公开(公告)日:2023-03-16
申请号:US17658783
申请日:2022-04-11
申请人: Elekta, Inc.
发明人: Michel Moreau
摘要: Techniques are described for contouring of a region of interest based on imaging parameters of spatial imaging data and guided by user input of locations in the spatial imaging data, which may be used for segmentation or radiation treatment planning. An approach is described of combining a new paint brush tool with an edge-detection algorithm to correct for both the jagged contours and the painting routine not being executed often enough. By using an edge-detection algorithm, the user does not need to focus as much attention on moving the mouse accurately because the system will find the true organ boundary (e.g., using the image gradient) automatically, which may also lead to more time savings.
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公开(公告)号:US20200061389A1
公开(公告)日:2020-02-27
申请号:US16665360
申请日:2019-10-28
申请人: Elekta, Inc.
摘要: The present disclosure relates to a method for use in adaptive radiotherapy and a treatment planning device. The method may comprise accessing a first medical image and a second medical image that represent a region of interest of a patient at different times. Each medical image is segmented into a target region and at least one non-target region. The method may further comprise accessing a deformation vector field including a plurality of vectors, wherein each vector defines a geometric transformation to map a respective voxel in the first medical image to a corresponding voxel in the second medical image. The method may further comprise generating a modified deformation vector field by: identifying a first vector in the deformation vector field that maps a voxel in the first medical image to a voxel that is in a non-target region in the second medical image; and determining whether the first vector causes a distance between the mapped voxel and the target region to increase and, if so, reducing the magnitude of the first vector. The method may further comprise post-processing the modified deformation vector field to compensate for changes in the shape or size of the target region.
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公开(公告)号:US20190175940A1
公开(公告)日:2019-06-13
申请号:US15836474
申请日:2017-12-08
申请人: Elekta, Inc.
发明人: Sami Hissoiny , Michel Moreau
IPC分类号: A61N5/10
CPC分类号: A61N5/1031 , A61N5/1037 , A61N5/1038 , A61N5/1039 , A61N5/1064 , A61N2005/1034 , A61N2005/1052 , A61N2005/1055 , A61N2005/1058 , A61N2005/1061
摘要: Radiation treatment planning and administration can include a Monte Carlo computer simulation tool to simulate photo-generated electrons in tissue. In the simulation, electrons that have left tissue voxels and entered air voxels can be evaluated to identify electrons that are circling along a spiraling trajectory in the air voxels. After at least one full spiraling circumference or other specified distance has been traversed using a detailed electron transport model, a simpler linear ballistic motion model can be instituted. This speeds simulation while accurately accounting for spiraling electrons that re-enter tissue voxels.
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公开(公告)号:US10300305B2
公开(公告)日:2019-05-28
申请号:US15957056
申请日:2018-04-19
申请人: Elekta, Inc.
摘要: An adaptive therapy delivery system can receive imaging information including a volumetric image comprising a target such as a tumor or one or more other structures, and can receive imaging information corresponding to one or more imaging slices comprising different portions of the target, such as imaging slices acquired at different times after acquisition of the volumetric image. The system can spatially register information from an earlier-acquired image with a portion of the target included in a later-acquired one of the imaging slices. The system can then determine an updated location of the target indicated by the spatially-registered information. Using the updated location, the system can generate an updated therapy protocol to control delivery of a therapy beam.
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公开(公告)号:US10300303B2
公开(公告)日:2019-05-28
申请号:US15387689
申请日:2016-12-22
申请人: Elekta Ltd. , ELEKTA, INC.
摘要: An image-guided therapy delivery system includes a therapy generator configured to generate a therapy beam directed to a time-varying therapy locus within a therapy recipient, an imaging input configured to receive imaging information about a time-varying target locus within the therapy recipient, and a therapy controller. The therapy generator includes a therapy output configured to direct the therapy beam according to a therapy protocol. The therapy controller is configured to automatically generate a predicted target locus using information indicative of an earlier target locus extracted from the imaging information, a cyclic motion model, and a specified latency, and automatically generate an updated therapy protocol to align the time-varying therapy locus with the predicted target locus.
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公开(公告)号:US20180243585A1
公开(公告)日:2018-08-30
申请号:US15957056
申请日:2018-04-19
申请人: Elekta, Inc.
CPC分类号: A61N5/1065 , A61B5/055 , A61B6/032 , A61B8/085 , A61B2034/2065 , A61B2090/367 , A61N5/1037 , A61N5/1038 , A61N5/1039 , A61N5/1049 , A61N2005/1055 , A61N2005/1058 , A61N2005/1061 , G06T7/11 , G06T7/337 , G06T2207/10081 , G06T2207/10088 , G06T2207/10132 , G06T2207/20021 , G06T2207/30096
摘要: An adaptive therapy delivery system can receive imaging information including a volumetric image comprising a target such as a tumor or one or more other structures, and can receive imaging information corresponding to one or more imaging slices comprising different portions of the target, such as imaging slices acquired at different times after acquisition of the volumetric image. The system can spatially register information from an earlier-acquired image with a portion of the target included in a later-acquired one of the imaging slices. The system can then determine an updated location of the target indicated by the spatially-registered information. Using the updated location, the system can generate an updated therapy protocol to control delivery of a therapy beam.
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