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    Treatment and planning for lymphocytes sparing radiotherapy
    2.
    发明授权
    Treatment and planning for lymphocytes sparing radiotherapy 有权

    公开(公告)号：US12102842B2

    公开(公告)日：2024-10-01

    申请号：US17802766

    申请日：2021-02-26

    Applicant: Universiteit Maastricht

    Inventor： Philippe Lambin ,  Ludwig Jerome Dubois

    IPC: A61N5/10

    CPC classification number: A61N5/1031 ,  A61N5/1064 ,  A61N5/1071 ,  A61N2005/1087

    Abstract: The present document relates to providing a radiation treatment plan for treatment of a neoplasm, including the steps of: obtaining an image including the neoplasm and obtaining first segmentation data for segmenting at least one target-volume to be targeted with radiation. Further identifying any organs-at-risk and segmenting these. The method further comprises identifying lymphocyte-rich-organs in the image, and obtaining third segmentation data for segmenting the lymphocyte-rich-organs. The planning system then obtains radiation dose regime data, including first, second and third dose regime data. The planning system then determines a radiation treatment plan which provides treatment process parameters for operating one or more radiation beams for radiation treatment of the neoplasm, The process parameters are determined to apply the radiation at a first radiation dose to the target volume which corresponds with the first dose regime data, apply the radiation at a minimized second radiation dose to the or each organs-at-risk, and apply the radiation at a third radiation dose to the or each lymphocyte-rich-organ which corresponds with the third dose regime data, wherein the third radiation dose amount is minimized.

    SYSTEMS AND METHODS FOR FAULT DETECTION IN EMISSION-GUIDED RADIOTHERAPY
    3.
    发明公开
    SYSTEMS AND METHODS FOR FAULT DETECTION IN EMISSION-GUIDED RADIOTHERAPY 审中-公开

    公开(公告)号：US20240316365A1

    公开(公告)日：2024-09-26

    申请号：US18731698

    申请日：2024-06-03

    Applicant: RefleXion Medical, Inc.

    Inventor： Peter Demetri OLCOTT ,  Matthew Francis BIENIOSEK

    IPC: A61N5/10

    CPC classification number: A61N5/1075 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1081 ,  A61N2005/1052 ,  A61N2005/1095

    Abstract: Disclosed herein are systems and methods for monitoring calibration of positron emission tomography (PET) systems. In some variations, the systems include an imaging assembly having a gantry comprising a plurality of positron emission detectors. A housing may be coupled to the gantry, and the housing may include a bore and a radiation source holder spaced away from a patient scan region within the bore. A processor may be configured to receive positron emission data from the positron emission detectors and to distinguish the positron emission data from the radiation source holder and from the patient scan region. A fault signal may be generated when the positron emission data from the radiation source holder exceeds one or more threshold parameters or criteria.

    Ionizing-radiation beamline monitoring system
    4.
    发明授权
    Ionizing-radiation beamline monitoring system 有权

    公开(公告)号：US12017091B2

    公开(公告)日：2024-06-25

    申请号：US18462606

    申请日：2023-09-07

    Applicant: Integrated Sensors, LLC

    Inventor： Peter S. Friedman

    IPC: A61N5/10 ,  A61N5/00 ,  G01T1/40 ,  G01T1/161 ,  G01T1/29

    CPC classification number: A61N5/1067 ,  A61N5/00 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1064 ,  G01T1/40 ,  A61N2005/1059 ,  A61N5/1077 ,  A61N2005/1087 ,  G01T1/1612 ,  G01T1/29

    Abstract: Embodiments are directed generally to an ionizing-radiation beamline monitoring system that includes a vacuum chamber structure with vacuum compatible flanges through which an incident ionizing-radiation beam enters the monitoring system. Embodiments further include at least one scintillator within the vacuum chamber structure that can be at least partially translated in the ionizing-radiation beam while oriented at an angle greater than 10 degrees to a normal of the incident ionizing-radiation beam, a machine vision camera coupled to a light-tight structure at atmospheric/ambient pressure that is attached to the vacuum chamber structure by a flange attached to a vacuum-tight viewport window with the camera and lens optical axis oriented at an angle of less than 80 degrees with respect to a normal of the scintillator, and at least one ultraviolet (“UV”) illumination source facing the scintillator in the ionizing-radiation beam for monitoring a scintillator stability comprising scintillator radiation damage.

    Method for real-time correction of a spatial position of a central beam of radiation therapy devices and of a patient position
    6.
    发明授权
    Method for real-time correction of a spatial position of a central beam of radiation therapy devices and of a patient position 有权

    公开(公告)号：US11986675B2

    公开(公告)日：2024-05-21

    申请号：US17286808

    申请日：2019-11-06

    Applicant: STÄDTISCHES KLINIKUM DESSAU

    Inventor： Markus Wösle

    IPC: A61N5/10

    CPC classification number: A61N5/1064 ,  A61N5/103 ,  A61N5/1045 ,  A61N5/1047 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107

    Abstract: A method provides real-time correction of the spatial position of the central beam of radiation therapy devices and therapy simulators, along with the patient position. In particular, the method relates to the real-time correction of irradiation positions of the collimator and/or the position of the patient positioning table during the performance of radiation therapy or therapy simulation. Positional deviations of the central beam of existing radiation therapy devices are reduced. Position adjustments of the collimator elements and/or of the patient support table are carried out through functional connections of separate control modules via separate adjustment devices. Those are added to the collimator and/or patient support table. Calculation of the correction movements takes place outside the radiation therapy device in the irradiation planning system and/or in at least one microcontroller of the control system of the radiation therapy device.

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