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公开(公告)号：US11456518B2
公开(公告)日：2022-09-27
申请号：US16896096
申请日：2020-06-08
摘要： A method for manufacturing a radio frequency (RF) applicator which includes covering a ceramic insert with a coating, wherein the ceramic insert has dimensions that substantially match an internal volume of an open-ended, hollow waveguide, and wherein the ceramic insert has a recess therein configured to accept a radio frequency emitter, heating the waveguide to a temperature that is above a melting point of the coating, placing the coated ceramic insert into the internal volume of the heated waveguide, wherein the internal volume is completely filled except for the recess, and cooling the waveguide, ceramic insert, and coating to a temperature below the melting point of the coating so that the coating solidifies and fills gaps between facing surfaces of the insert and the waveguide.
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2.发明授权公开(公告)号：US11994549B1
公开(公告)日：2024-05-28
申请号：US18401526
申请日：2023-12-31
CPC分类号： G01R29/10 , G01R29/0821 , G01R29/0878
摘要： A method for determining an electromagnetic field spatial distribution of a radio frequency (RF) antenna which includes the steps of emitting with the RF antenna, a plurality of RF energy pulses into a homogeneous medium; performing a plurality of thermoacoustic signal measurements of the plurality of RF energy pulses, wherein each of the thermoacoustic signal measurements is performed in a similar manner; utilizing a variance in the plurality of thermoacoustic signal measurements to generate a reconstructed pressure distribution for a volume located within the homogeneous medium; and calculating the RF antenna electromagnetic field spatial distribution within the volume based upon the reconstructed pressure distribution for the volume located within the homogeneous medium.
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公开(公告)号：US11844650B1
公开(公告)日：2023-12-19
申请号：US18130192
申请日：2023-04-03
CPC分类号： A61B8/485 , G01N29/043 , G01N29/0654 , G01N29/2431 , G02F1/2255
摘要： A thermoacoustic measurement probe includes an open-ended hollow radio-frequency (RF) waveguide; at least two RF feeds positioned within the open-ended hollow RF waveguide, wherein each RF feed is configured to provide RF energy; and a thermoacoustic transducer, wherein the open-ended hollow RF waveguide, in the form of a sleeve, surrounds and is mechanically joined to the thermoacoustic transducer.
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公开(公告)号：US11369272B1
公开(公告)日：2022-06-28
申请号：US17554675
申请日：2021-12-17
摘要： An RF applicator has an open-ended waveguide having an aperture and a dielectric cone extending through the aperture and is electrically connected to an RF source that is configured to generate RF energy pulses. A top fin is mounted to an inner top surface of the waveguide and comprises a conductive material, is electrically connected to the RF source, and has dimensions configured to optimize a bandwidth that the RF applicator applies to tissue. A bottom fin is mounted to an inner bottom surface of the waveguide and comprises a conductive material electrically isolated from the RF source, with dimensions configured to optimize a bandwidth that the RF applicator applies to tissue. A dielectric cone is inserted into the waveguide. A filler material between inner surfaces of the waveguide and the solid dielectric cone can fill gaps and has a dielectric constant similar to the dielectric cone.
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公开(公告)号：US20200303803A1
公开(公告)日：2020-09-24
申请号：US16896096
申请日：2020-06-08
摘要： A method for manufacturing a radio frequency (RF) applicator which includes covering a ceramic insert with a coating, wherein the ceramic insert has dimensions that substantially match an internal volume of an open-ended, hollow waveguide, and wherein the ceramic insert has a recess therein configured to accept a radio frequency emitter, heating the waveguide to a temperature that is above a melting point of the coating, placing the coated ceramic insert into the internal volume of the heated waveguide, wherein the internal volume is completely filled except for the recess, and cooling the waveguide, ceramic insert, and coating to a temperature below the melting point of the coating so that the coating solidifies and fills gaps between facing surfaces of the insert and the waveguide.
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公开(公告)号：US10682059B1
公开(公告)日：2020-06-16
申请号：US16235039
申请日：2018-12-28
摘要： A radio frequency applicator comprises an open-ended, hollow waveguide having an aperture therein. A solid insert is positioned within the waveguide. The solid insert has a recess formed therein that is aligned with the aperture. Filler material is provided between facing surfaces of the waveguide and the insert to fill gaps therebetween. A radio frequency (RF) source extends through the aperture and into the recess and is configured to generate RF energy pulses.
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公开(公告)号：US11337676B2
公开(公告)日：2022-05-24
申请号：US16714848
申请日：2020-02-12
摘要： A method and system for optimizing RF energy delivery to a tissue ROI with a thermoacoustic system includes directing with a RF applicator, RF energy pulses into the tissue ROI having an object of interest and a reference separated by a boundary; detecting with a thermoacoustic transducer, a multi-polar thermoacoustic signal generated at the boundary in response to the RF energy pulses and processing the multi-polar acoustic signal to determine a peak-to-peak amplitude; detecting with the thermoacoustic transducer, an artifact multi-polar thermoacoustic signal generated at a location other than the boundary and processing it to determine a peak-to-peak amplitude; utilizing an electromagnetic model coupled with a model of patient anatomy to place dielectric or conducting materials near the thermoacoustic transducer or the RF applicator to optimize a signal-to-noise ratio of the multi-polar thermoacoustic signal generated at the boundary or minimize the artifact multi-polar thermoacoustic signal generated at a location other than the boundary; and directing with the RF applicator, RF energy pulses into the ROI for a thermoacoustic measurement and determine a parameter of the object of interest.
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公开(公告)号：US11304606B2
公开(公告)日：2022-04-19
申请号：US16182650
申请日：2018-11-07
摘要： A method and system for enhancing radio frequency energy delivery to a tissue region of interest. The method and system direct with a radio frequency (RF) applicator, one or more RF energy pulses into the tissue region of interest, the tissue region of interest comprising an object of interest and at least one reference that are separated by at least one boundary; detect with an acoustic receiver, at least one bipolar acoustic signal generated in the tissue region of interest in response to the RF energy pulses and processing the at least one bipolar acoustic signal to determine a peak-to-peak amplitude thereof; adjust the RF applicator to maximize the peak-to-peak amplitude of bipolar acoustic signals generated in the tissue region of interest in response to RF energy pulses generated by the adjusted RF applicator; and direct with the adjusted RF applicator, one or more RF energy pulses into the region of interest.
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公开(公告)号：US20210321873A1
公开(公告)日：2021-10-21
申请号：US17230480
申请日：2021-04-14
摘要： A thermoacoustic transducer integrating at least one piezoelectric element having a first surface and a second surface, a potential electrode that is electrically connected to the second surface, a ground electrode that is electrically connected to the first surface, a switch electrically connected to both the potential electrode and the ground electrode, a timer configured to match a pulse emanating from a radio-frequency emitter, further wherein the potential electrode and the ground electrode are electrically connected through an impedance when the switch is in an active state, further wherein the potential electrode and the ground electrode are not electrically connected when the switch is in an inactive state; and a housing accommodating the at least one piezoelectric element, potential electrode, ground electrode, and switch.
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公开(公告)号：US20210244384A1
公开(公告)日：2021-08-12
申请号：US16714848
申请日：2020-02-12
摘要： A method and system for optimizing RF energy delivery to a tissue ROI with a thermoacoustic system includes directing with a RF applicator, RF energy pulses into the tissue ROI having an object of interest and a reference separated by a boundary; detecting with a thermoacoustic transducer, a multi-polar thermoacoustic signal generated at the boundary in response to the RF energy pulses and processing the multi-polar acoustic signal to determine a peak-to-peak amplitude; detecting with the thermoacoustic transducer, an artifact multi-polar thermoacoustic signal generated at a location other than the boundary and processing it to determine a peak-to-peak amplitude; utilizing an electromagnetic model coupled with a model of patient anatomy to place dielectric or conducting materials near the thermoacoustic transducer or the RF applicator to optimize a signal-to-noise ratio of the multi-polar thermoacoustic signal generated at the boundary or minimize the artifact multi-polar thermoacoustic signal generated at a location other than the boundary; and directing with the RF applicator, RF energy pulses into the ROI for a thermoacoustic measurement and determine a parameter of the object of interest.
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