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1.发明授权公开(公告)号：US10478393B2
公开(公告)日：2019-11-19
申请号：US15564806
申请日：2016-03-30
Applicant: ISP Investments LLC , ELC Management LLC
Inventor： Frédérique Portolan , Jean-Marie Botto , Joel Mantelin , Isabelle Imbert , Nouha Domloge , Daniel B. Yarosh , Nevena Jurukovska-Karaman , Nadine A. Perdonet , Kelly Dong , Edward Pelle
IPC: A61K36/87 , A61K8/9794 , A61Q19/00 , A61Q19/08 , A61K8/9789
Abstract: The present invention relates to the cosmetic use of a combination of a hydrolysed rice extract and a grapeseed extract as an active agent to protect cutaneous cells from pollution. The present invention relates also to a cosmetic method of treatment for protecting skin epidermal cells from atmospheric pollution comprising applying on the skin area to be treated a composition comprising a combination of a hydrolysed rice extract and a grapeseed extract.
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公开(公告)号：US10821069B2
公开(公告)日：2020-11-03
申请号：US15324299
申请日：2015-07-07
Applicant: ISP INVESTMENTS LLC , ELC MANAGEMENT LLC
Inventor： Frédérique Portolan , Valerie Lequoy , Jean-Marie Botto , Joel Mantelin , Isabelle Imbert , Nouha Domloge , Noelle Garcia , Nadine A. Pernodet , Kelly Dong , Edward Pelle , Carl Haney
IPC: A61Q17/04 , A61Q19/08 , A61K8/9728 , A61K8/9789 , A61K8/9794
Abstract: The invention relates to a Truffle extract for skin cosmetic use, comprising compounds having a molecular weight of less than 5 kDa. The invention also relates to a cosmetic method of treatment designed to reduce and/or correct the signs of aging and photo-aging of the skin and keratinous appendages, and to protect the skin against aggressions due to ultraviolet radiation.
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公开(公告)号：US11673905B2
公开(公告)日：2023-06-13
申请号：US15776232
申请日：2016-11-10
Applicant: ELC Management LLC , ISP Investments LLC
Inventor： Elodie Oger , Rachel Chabert , Isabelle Imbert , Jean-Marie Botto , Nouha Domloge , Joel Mantelin , Nadine Pernodet , Kelly Dong , Chia-Wen Chen
IPC: A61K8/44 , C07H1/08 , A61K8/60 , C07H21/02 , A61Q19/08 , A61K8/9789 , C12N15/10 , A61Q19/00 , A61Q17/04 , A61K8/9794
CPC classification number: C07H1/08 , A61K8/44 , A61K8/606 , A61K8/9789 , A61K8/9794 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/08 , C07H21/02 , C12N15/1003 , C12N15/1017 , A61K2800/10 , A61K2800/30 , A61K2800/805
Abstract: The invention relates to a topical composition comprising an extract of Tiger lily (Lilium tigrinum) enriched in low molecular weight RNA. The invention also relates to a method of cosmetic care including the topical application a composition comprising an extract of Tiger lily (Lilium tigrinum) in a physiologically acceptable medium, in order to reduce skin signs of aging and photo-aging. The invention is also directed to a cosmetic method of treatment to improve cell viability, to improve cell protection against particulate matter and against DNA damages, and to reduce cellular senescence.
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公开(公告)号：US20180125778A1
公开(公告)日：2018-05-10
申请号：US15794672
申请日：2017-10-26
Applicant: ELC Management LLC
Inventor： Nadine Pernodet , Klodjan Stafa , Edward Pelle , Kelly Dong , Earl Goyarts , Dawn Layman , Krystle Corallo
IPC: A61K9/00 , C12N15/113 , A61K35/745 , A61K36/185 , A61K38/06 , A61K38/43
CPC classification number: A61K9/0014 , A61K35/745 , A61K35/747 , A61K36/07 , A61K36/185 , A61K36/882 , A61K38/06 , A61K38/07 , A61K38/43 , C12N15/113 , C12N2310/141 , C12N2320/31 , A61K2300/00
Abstract: Topical compositions containing at least one ingredient that stimulates Mir-146a activity in skin cells, methods for treating skin and methods for screening for ingredients that stimulate Mir-146a activity.
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公开(公告)号：US09539196B2
公开(公告)日：2017-01-10
申请号：US14949967
申请日：2015-11-24
Applicant: ELC Management LLC
Inventor： Nadine Pernodet , Kelly Dong , Edward Pelle
CPC classification number: A61K8/64 , A61K8/66 , A61K8/99 , A61Q17/04 , A61Q19/08 , C12Y302/02 , C12Y305/01 , C12Y402/99018
Abstract: Compositions of the invention comprise 8-oxoguanine glycosylase (OGG1) and SIRT6 activating peptide G-A-G-V-S-A-E-NH2. Compositions of the invention exhibit anti-aging effects by promoting the repair of skin cell DNA and/or by protecting skin cell DNA from UV damage.
Abstract translation: 本发明的组合物包含8-氧基鸟嘌呤糖基化酶（OGG1）和SIRT6活化肽G-A-G-V-S-A-E-NH 2。 本发明的组合物通过促进皮肤细胞DNA的修复和/或通过保护皮肤细胞DNA免受紫外线损伤而显示抗衰老作用。
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Patent Agency Ranking
公开(公告)号：US10537517B2
公开(公告)日：2020-01-21
申请号：US16034157
申请日：2018-07-12
Applicant: ELC Management LLC
Inventor： Nadine A. Pernodet , Kelly Dong , Edward Pelle , Daniel B. Yarosh
Abstract: A skin care composition for stimulating selective catabolysis in cells of keratin surfaces comprising at least one autophagy activator and at least one proteasome activator, and a method for improving selective catabolysis in cells of keratin surfaces by treating with the composition.
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7.发明申请公开(公告)号：US20190201322A9
公开(公告)日：2019-07-04
申请号：US14019598
申请日：2013-09-06
Applicant: ELC Management LLC
Inventor： Nadine A. Pernodet , Kelly Dong , Edward Pelle , Daniel B. Yarosh
Abstract: A skin care composition for stimulating selective catabolysis in cells of keratin surfaces comprising at least one autophagy activator and at least one proteasome activator, and a method for improving selective catabolysis in cells of keratin surfaces by treating with the composition.
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公开(公告)号：US10383815B2
公开(公告)日：2019-08-20
申请号：US14019598
申请日：2013-09-06
Applicant: ELC Management LLC
Inventor： Nadine A. Pernodet , Kelly Dong , Edward Pelle , Daniel B. Yarosh
Abstract: A skin care composition for stimulating selective catabolysis in cells of keratin surfaces comprising at least one autophagy activator and at least one proteasome activator, and a method for improving selective catabolysis in cells of keratin surfaces by treating with the composition.
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公开(公告)号：US10022314B2
公开(公告)日：2018-07-17
申请号：US15365109
申请日：2016-11-30
Applicant: ELC Management LLC
Inventor： Nadine Pernodet , Kelly Dong , Edward Pelle
Abstract: Compositions of the invention comprise 8-oxoguanine glycosylase (OGG1) and SIRT6 activating peptide G-A-G-V-S-A-E-NH2. Compositions of the invention exhibit anti-aging effects by promoting the repair of skin cell DNA and/or by protecting skin cell DNA from UV damage.
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10.发明申请Compositions Comprising A Sirt6 Activator As A Component Of A Yeast Ferment Extract And A DNA Repair Enzyme 审中-公开包含Sirt6活化剂作为酵母发酵提取物和DNA修复酶的组分的组合物公开(公告)号：US20170071845A1
公开(公告)日：2017-03-16
申请号：US15365109
申请日：2016-11-30
Applicant: ELC Management LLC
Inventor： Nadine Pernodet , Kelly Dong , Edward Pelle
CPC classification number: A61K8/64 , A61K8/66 , A61K8/99 , A61Q17/04 , A61Q19/08 , C12Y302/02 , C12Y305/01 , C12Y402/99018
Abstract: Compositions of the invention comprise 8-oxoguanine glycosylase (OGG1) and SIRT6 activating peptide G-A-G-V-S-A-E-NH2. Compositions of the invention exhibit anti-aging effects by promoting the repair of skin cell DNA and/or by protecting skin cell DNA from UV damage.
Abstract translation: 本发明的组合物包含8-氧基鸟嘌呤糖基化酶（OGG1）和SIRT6活化肽G-A-G-V-S-A-E-NH 2。 本发明的组合物通过促进皮肤细胞DNA的修复和/或通过保护皮肤细胞DNA免受紫外线损伤而显示抗衰老作用。
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