公开(公告)号：US20180289696A1

公开(公告)日：2018-10-11

申请号：US15887797

申请日：2018-02-02

Applicant: Durect Corporation

Inventor： Su Il Yum ,  Grant Schoenhard ,  Arthur J. Tipton ,  John W. Gibson ,  John C. Middleton ,  Roger Fu ,  Michael S. Zamloot

IPC: A61K31/485 ,  A61K47/14 ,  A61K31/4458 ,  A61K47/26 ,  A61K9/48 ,  A61K9/00 ,  A61K47/38

Abstract: Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of compounds.

公开(公告)号：US09517271B2

公开(公告)日：2016-12-13

申请号：US14957148

申请日：2015-12-02

Applicant: Durect Corporation

Inventor： Su Il Yum ,  Grant Schoenhard ,  Arthur J. Tipton ,  John W. Gibson ,  John C. Middleton ,  Roger Fu ,  Michael S. Zamloot

IPC: A61K47/38 ,  A61K9/48 ,  A61K47/26 ,  A61K47/14 ,  A61K31/485 ,  A61K31/4458

CPC classification number: A61K31/485 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4825 ,  A61K9/4858 ,  A61K9/4866 ,  A61K31/4458 ,  A61K47/14 ,  A61K47/26 ,  A61K47/38 ,  Y10S514/96

Abstract: Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of compounds.

公开(公告)号：US08945614B2

公开(公告)日：2015-02-03

申请号：US13786118

申请日：2013-03-05

Applicant: Durect Corporation

Inventor： Su Il Yum ,  Grant Schoenhard ,  Arthur J. Tipton ,  John W. Gibson ,  John C. Middleton ,  Roger Fu ,  Michael S. Zamloot

IPC: A61K9/64 ,  A61K31/44 ,  A61K47/00 ,  A61K9/48 ,  A61K31/485 ,  A61K47/26 ,  A61K31/4458

CPC classification number: A61K31/485 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4825 ,  A61K9/4858 ,  A61K9/4866 ,  A61K31/4458 ,  A61K47/14 ,  A61K47/26 ,  A61K47/38 ,  Y10S514/96

Abstract: Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of compounds.

公开(公告)号：US20130295168A1

公开(公告)日：2013-11-07

申请号：US13786109

申请日：2013-03-05

Applicant: Durect Corporation

Inventor： Su Il Yum ,  Grant Schoenhard ,  Arthur J. Tipton ,  John W. Gibson ,  John C. Middleton

IPC: A61K9/48 ,  A61K31/485

CPC classification number: A61K31/485 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4825 ,  A61K9/4858 ,  A61K9/4866 ,  A61K31/4458 ,  A61K47/14 ,  A61K47/26 ,  A61K47/38 ,  Y10S514/96

Abstract: Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of compounds.

公开(公告)号：US20130287845A1

公开(公告)日：2013-10-31

申请号：US13786110

申请日：2013-03-05

Applicant: Durect Corporation

Inventor： Su Il Yum ,  Grant Schoenhard ,  Arthur J. Tipton ,  John W. Gibson ,  John C. Middleton

IPC: A61K9/48 ,  A61K31/4458 ,  A61K31/485

CPC classification number: A61K31/485 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4825 ,  A61K9/4858 ,  A61K9/4866 ,  A61K31/4458 ,  A61K47/14 ,  A61K47/26 ,  A61K47/38 ,  Y10S514/96

Abstract: Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of compounds.

公开(公告)号：US08974821B2

公开(公告)日：2015-03-10

申请号：US13786109

申请日：2013-03-05

Applicant: Durect Corporation

Inventor： Su Il Yum ,  Grant Schoenhard ,  Arthur J. Tipton ,  John W. Gibson ,  John C. Middleton ,  Roger Fu ,  Michael S. Zamloot

IPC: A61K9/64 ,  A61K31/44 ,  A61K47/00 ,  A61K9/48 ,  A61K31/485 ,  A61K47/26 ,  A61K31/4458

CPC classification number: A61K31/485 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4825 ,  A61K9/4858 ,  A61K9/4866 ,  A61K31/4458 ,  A61K47/14 ,  A61K47/26 ,  A61K47/38 ,  Y10S514/96

Abstract: Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of compounds.

公开(公告)号：US20140342985A1

公开(公告)日：2014-11-20

申请号：US14259033

申请日：2014-04-22

Applicant: DURECT CORPORATION

Inventor： John W. Gibson ,  Arthur J. Tipton

IPC: A61K47/34 ,  A61K38/09

CPC classification number: A61K47/34 ,  A61K9/0024 ,  A61K9/1635 ,  A61K9/1647 ,  A61K9/2031 ,  A61K38/09 ,  A61K38/24

Abstract: Polymeric devices for controlled release of an active agent of interest are provided. The active agent is provided within a biodegradable polymer system to supply a polymeric device for controlled release of the active agent. The polymer system is a copolymer or a polymer blend comprising a hydrophobic component and a hydrophilic component, and the polymer system does not form a hydrogel when contacted with, or immersed in an aqueous system, for example when the device is implanted in a subject. When the device is administered to a subject, for example, when it is implanted, the device releases the active agent in a controlled fashion without a lag period, or with a minimal lag period. Methods for producing the polymeric devices are also provided, as are methods of using the polymeric devices to provide for controlled release of an active agent in a subject.

Abstract translation: 提供了用于感兴趣的活性剂的控制释放的聚合装置。 活性剂提供在可生物降解的聚合物体系内，以提供用于活性剂的受控释放的聚合物装置。 聚合物体系是包含疏水组分和亲水组分的共聚物或聚合物共混物，并且聚合物体系当与例如当将该装置植入受试者中时与水系统接触或浸没在水系统中时不形成水凝胶。 当将装置施用于受试者时，例如，当其被植入时，该装置以受控的方式释放活性剂，而没有滞后期或具有最小滞后期。 还提供了生产聚合物装置的方法，以及使用聚合物装置来提供受试者中活性剂的受控释放的方法。

公开(公告)号：US20130281480A1

公开(公告)日：2013-10-24

申请号：US13786118

申请日：2013-03-05

Applicant: Durect Corporation

Inventor： Su Il Yum ,  Grant Schoenhard ,  Arthur J. Tipton ,  John W. Gibson ,  John C. Middleton

IPC: A61K47/26

CPC classification number: A61K31/485 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4825 ,  A61K9/4858 ,  A61K9/4866 ,  A61K31/4458 ,  A61K47/14 ,  A61K47/26 ,  A61K47/38 ,  Y10S514/96

Abstract: Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of compounds.

公开(公告)号：US09918982B2

公开(公告)日：2018-03-20

申请号：US15342956

申请日：2016-11-03

Applicant: DURECT CORPORATION

Inventor： Su Il Yum ,  Grant Schoenhard ,  Arthur J. Tipton ,  John W. Gibson ,  John C. Middleton ,  Roger Fu ,  Michael S. Zamloot

IPC: A61K31/485 ,  A61K47/38 ,  A61K9/00 ,  A61K9/48 ,  A61K47/26 ,  A61K47/14 ,  A61K31/4458

CPC classification number: A61K31/485 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4825 ,  A61K9/4858 ,  A61K9/4866 ,  A61K31/4458 ,  A61K47/14 ,  A61K47/26 ,  A61K47/38 ,  Y10S514/96

Abstract: Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of compounds.

公开(公告)号：US20170165255A1

公开(公告)日：2017-06-15

申请号：US15342956

申请日：2016-11-03

Applicant: DURECT CORPORATION

Inventor： Su Il Yum ,  Grant Schoenhard ,  Arthur J. Tipton ,  John W. Gibson ,  John C. Middleton ,  Roger Fu ,  Michael S. Zamloot

IPC: A61K31/485 ,  A61K9/00 ,  A61K9/48

CPC classification number: A61K31/485 ,  A61K9/0053 ,  A61K9/48 ,  A61K9/4825 ,  A61K9/4858 ,  A61K9/4866 ,  A61K31/4458 ,  A61K47/14 ,  A61K47/26 ,  A61K47/38 ,  Y10S514/96

Abstract: Dosage forms and drug delivery devices suitable for administration of pharmaceutical compounds and compositions, including the oral drug administration of compounds.