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1.发明申请公开(公告)号：US20190300887A1
公开(公告)日：2019-10-03
申请号：US15937622
申请日：2018-03-27
申请人： Dominic Man-Kit Lam , Olivia Yee-Yee Lam , Han Lei
发明人： Dominic Man-Kit Lam , Olivia Yee-Yee Lam , Han Lei
IPC分类号： C12N15/81 , G01N33/576 , A61K39/29 , A61K9/00 , A61K9/48
摘要： In the invention described here, the approach is to formulate an edible vaccine based on N-terminal yeast surface display expression platform that producing S.cerevisiae EBY100/pYD5-preS2/S(adw) and S.cerevisiae EBY100/pYD5-preS2/S(adr) for protecting and treating human against hepatitis B virus (HBV) infection, suggesting that yeast surface display expression system expressing HBsAg antigen has potential as a prophylactic treatment for HBV in human via oral vaccination. The technology developed in this patent application can also be used to produce edible (oral) vaccines for preventing and treating other infectious diseases in human.
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公开(公告)号：US11103571B2
公开(公告)日：2021-08-31
申请号：US16847342
申请日：2020-04-13
摘要： In the invention described here, the approach is to formulate an edible vaccine based on N-terminal yeast surface display expression systems including S. cerevisiae EBY100/pYD5-VP28, S. cerevisiae EBY100/pYD5-VP28-VP24 and S. cerevisiae EBY100/pYD5-VP24 for preventing shrimps such as L. vannamei, P. monodon and M. rosenbergii species from white spot syndrome virus (WSSV) infection, suggesting that yeast surface display expression system expressing WSSV antigen has potential as a prophylactic treatment for WSSV in shrimps via oral vaccination. The technology developed in this patent application can also be used to produce edible (oral) vaccines for preventing and treating other infectious diseases in animals and human.
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公开(公告)号：US10793866B2
公开(公告)日：2020-10-06
申请号：US15937622
申请日：2018-03-27
申请人： Dominic Man-Kit Lam , Olivia Yee-Yee Lam , Han Lei
发明人： Dominic Man-Kit Lam , Olivia Yee-Yee Lam , Han Lei
IPC分类号： A61K38/00 , A61K39/00 , C07K14/00 , A61K38/16 , A61K39/12 , C12N15/81 , G01N33/576 , A61K39/29 , A61K9/48 , A61K9/00
摘要： In the invention described here, the approach is to formulate an edible vaccine based on N-terminal yeast surface display expression platform that producing S.cerevisiae EBY100/pYD5-preS2/S(adw) and S.cerevisiae EBY100/pYD5-preS2/S(adr) for protecting and treating human against hepatitis B virus (HBV) infection, suggesting that yeast surface display expression system expressing HBsAg antigen has potential as a prophylactic treatment for HBV in human via oral vaccination. The technology developed in this patent application can also be used to produce edible (oral) vaccines for preventing and treating other infectious diseases in human.
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4.发明申请公开(公告)号：US20190298817A1
公开(公告)日：2019-10-03
申请号：US15648863
申请日：2017-07-13
IPC分类号： A61K39/12
摘要： In the invention described here, the approach is to formulate an edible vaccine based on N-terminal yeast surface display expression systems including S. cerevisiae EBY100/pYD5-VP28, S. cerevisiae EBY100/pYD5-VP28-VP24 and S. cerevisiae EBY100/pYD5-VP24 for preventing shrimps such as L. vannamei, P. monodon and M. rosenbergii species from white spot syndrome virus (WSSV) infection, suggesting that yeast surface display expression system expressing WSSV antigen has potential as a prophylactic treatment for WSSV in shrimps via oral vaccination. The technology developed in this patent application can also be used to produce edible (oral) vaccines for preventing and treating other infectious diseases in animals and human.
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公开(公告)号：US09752739B2
公开(公告)日：2017-09-05
申请号：US13220002
申请日：2011-08-29
申请人： Steven Holscher , Han Lei
发明人： Steven Holscher , Han Lei
IPC分类号： F21S9/02 , F21S9/00 , F21V29/00 , F21V21/30 , F21V29/507 , F21V29/74 , F21Y115/10
CPC分类号： H02J9/061 , F21S9/022 , F21V21/30 , F21V29/507 , F21V29/74 , F21Y2115/10 , H02J7/007 , H02J7/022 , H02J7/041 , H02J7/045 , H03K5/24 , Y10T307/625
摘要： An emergency lighting assembly is provided having a housing with one or more adjustable lamp assemblies for aiming the light at selected areas. The lamp assembly is mounted in the housing by a ball and socket arrangement. The lamp assembly has a substantially spherical shape with a front section made of a heat conducting material and a rear section made of a plastic material. The front section has an opening on a front side having a lens and a base spaced from the front side supporting the light source. The light source in one embodiment is an LED which is coupled to the front section to conduct heat from the LED away from the LED and the housing. The rear section has an opening in the rear side that receives a fixed stop member to limit pivoting movement of the lamp assembly with respect to the housing. The rear section also includes a projection oriented to contact the stop member to limit rotation of the lamp assembly with respect to the housing.
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公开(公告)号：US08092936B2
公开(公告)日：2012-01-10
申请号：US12341787
申请日：2008-12-22
申请人： Zhou Xiankai , Han Lei , Gu Hongjuan , Shen Xi
发明人： Zhou Xiankai , Han Lei , Gu Hongjuan , Shen Xi
IPC分类号： H01M2/00
CPC分类号： H01M2/348 , H01M2/04 , H01M2/043 , H01M2/0456 , H01M2/046 , H01M2/0473 , H01M2/206 , H01M2/305 , H01M6/5038 , H01M10/0422 , H01M10/0431 , H01M10/0587 , H01M10/615 , H01M10/625 , H01M10/633 , H01M10/637 , H01M10/6553 , H01M10/6571 , H01M10/658 , Y02E60/12 , Y02T10/7011
摘要： There is disclosed a core for an electrochemical cell that comprises an anode sheet, a cathode sheet, and a separator sheet disposed between the anode sheet and cathode sheet. The anode sheet, cathode sheet, and separator sheet are wound to form a flattened coil structure. The flattened coil structure has opposed flattened sides and opposed arcuate sides. The anode and cathode sheets terminate at the same or different arcuate sides. Further, the separator sheet may terminate at one of the arcuate sides.
摘要翻译： 公开了一种用于电化学电池的芯，其包括阳极片，阴极片和布置在阳极片和阴极片之间的隔片片。 缠绕阳极片，阴极片和隔片片以形成扁平线圈结构。 扁平线圈结构具有相对的平坦侧面和相对的弧形侧面。 阳极和阴极片终止于相同或不同的弧形侧面。 此外，隔板可以在其中一个弧形侧面终止。
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公开(公告)号：US08865335B2
公开(公告)日：2014-10-21
申请号：US12341704
申请日：2008-12-22
申请人： Han Lei , Gu Hongjuan , Zheng Weixin , Shen Xi
发明人： Han Lei , Gu Hongjuan , Zheng Weixin , Shen Xi
IPC分类号： H01M6/10 , H01M10/615 , H01M10/6553 , H01M2/20 , H01M2/34 , H01M10/0587 , H01M10/6571 , H01M6/50 , H01M2/30 , H01M10/625 , H01M10/04 , H01M10/658 , H01M2/04
CPC分类号： H01M2/348 , H01M2/04 , H01M2/043 , H01M2/0456 , H01M2/046 , H01M2/0473 , H01M2/206 , H01M2/305 , H01M6/5038 , H01M10/0422 , H01M10/0431 , H01M10/0587 , H01M10/615 , H01M10/625 , H01M10/633 , H01M10/637 , H01M10/6553 , H01M10/6571 , H01M10/658 , Y02E60/12 , Y02T10/7011
摘要： An electrochemical storage cell is disclosed that comprises a cathode sheet, an anode sheet, and a separator sheet between the cathode and anode sheets. A metal foil current collector extends from a longitudinal edge of the cathode sheet. A further metal foil current collector extends from a longitudinal edge of the anode sheet. The anode sheet, cathode sheet, and separator sheet are wound in a flattened coil shape to produce a core in which the metal foil current collector of the cathode sheet extends beyond the separator sheet at one end of the core and the metal current collector of the anode sheet extends beyond the separator sheet at an opposite end of the core. Overlying layers of the metal foil current collector of the cathode sheet are compressed together and placed in electrical communication with a positive terminal of the cell while overlying layers of the metal foil current collector of the anode sheet are compressed together and placed in electrical communication a negative terminal of the cell.
摘要翻译： 公开了一种电化学蓄电池，其包括在阴极和阳极片之间的阴极片，阳极片和隔片片。 金属箔集电体从阴极片的纵向边缘延伸。 另外的金属箔集电体从阳极片的纵向边缘延伸出来。 阳极片，阴极片和隔片片卷绕成扁平的线圈形状，以制造核心，其中阴极片的金属箔集电器延伸超过芯的一端处的隔离片，并且金属集电体 阳极片在芯的相对端处延伸超过隔板。 阴极片的金属箔集电体的上层被压缩在一起并且与电池的正极端子电连通，同时阳极片的金属箔集电体的上层被压缩在一起并且被放置在电气连通中 终端的单元格。
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