公开(公告)号：US20060224329A1

公开(公告)日：2006-10-05

申请号：US11292185

申请日：2005-11-30

申请人： David Roth ,  Huaping He ,  Ben Good

发明人： David Roth ,  Huaping He ,  Ben Good

IPC分类号： G06F19/00

CPC分类号： G16B25/00 ,  G16B20/00 ,  G16B30/00 ,  G16B50/00 ,  Y02A90/26

摘要： Methods of rapidly generating and analyzing a plurality of polypeptides are disclosed. More specifically, libraries and arrays of polypeptides are assayed in order to determine their individual immunogenic effect. Based on the immunogenic effect of polypeptides, specific subunit vaccines can be developed.

公开(公告)号：US20060140982A1

公开(公告)日：2006-06-29

申请号：US11291616

申请日：2005-11-30

申请人： David Roth ,  Huaping He

发明人： David Roth ,  Huaping He

IPC分类号： A61K39/04 ,  C12Q1/68 ,  G01N33/554 ,  C07H21/04 ,  C12N15/74 ,  G01N33/569 ,  C07K14/35

CPC分类号： G01N33/5695 ,  A61K39/00 ,  A61K39/04 ,  A61K2039/53 ,  C07K14/35 ,  G01N2469/20

摘要： The present invention provides transcriptionally active Mtb polynucleotides, recombinant Mtb peptides and polypeptides, and immunogenic Mtb antigens. Immunogenic compositions are also provided that may be useful as recombinant, subunit and DNA vaccines. In addition the invention provides diagnostic kits for Mtb.

摘要翻译： 本发明提供转录活性Mtb多核苷酸，重组Mtb肽和多肽，以及免疫原性Mtb抗原。 还提供可用作重组，亚单位和DNA疫苗的免疫原性组合物。 此外，本发明提供了用于Mtb的诊断试剂盒。

公开(公告)号：US07608277B2

公开(公告)日：2009-10-27

申请号：US11291616

申请日：2005-11-30

申请人： David Roth ,  Huaping He

发明人： David Roth ,  Huaping He

IPC分类号： A61K39/04 ,  A61K49/00 ,  A61K39/00

CPC分类号： G01N33/5695 ,  A61K39/00 ,  A61K39/04 ,  A61K2039/53 ,  C07K14/35 ,  G01N2469/20

摘要： The present invention provides transcriptionally active Mtb polynucleotides, recombinant Mtb peptides and polypeptides, and immunogenic Mtb antigens. Immunogenic compositions are also provided that may be useful as recombinant, subunit and DNA vaccines. In addition, the invention provides diagnostic kits for Mtb.

摘要翻译： 本发明提供转录活性Mtb多核苷酸，重组Mtb肽和多肽，以及免疫原性Mtb抗原。 还提供可用作重组，亚单位和DNA疫苗的免疫原性组合物。 此外，本发明提供了用于Mtb的诊断试剂盒。

公开(公告)号：US20060222658A1

公开(公告)日：2006-10-05

申请号：US11291305

申请日：2005-11-30

申请人： David Roth ,  Huaping He

发明人： David Roth ,  Huaping He

IPC分类号： A61K39/12 ,  C07H21/04 ,  C12N15/86 ,  C12P21/06 ,  C07K14/07

CPC分类号： C07K14/005 ,  A61K39/12 ,  A61K39/285 ,  A61K2039/5154 ,  A61K2039/5156 ,  A61K2039/53 ,  C12N2710/24122 ,  C12N2710/24134

摘要： The present invention provides transcriptionally active vaccinia virus polynucleotides, recombinant vaccinia virus polypeptides, and immunogenic vaccinia virus antigens. Immunogenic compositions are also provided that may be useful as recombinant, subunit and DNA vaccines.

摘要翻译： 本发明提供转录活性痘苗病毒多核苷酸，重组痘苗病毒多肽和免疫原性痘苗病毒抗原。 还提供可用作重组，亚单位和DNA疫苗的免疫原性组合物。

公开(公告)号：US20100112008A1

公开(公告)日：2010-05-06

申请号：US12607024

申请日：2009-10-27

申请人： David Roth ,  Huaping He

发明人： David Roth ,  Huaping He

IPC分类号： A61K39/04 ,  C07H21/00 ,  A61P37/04

CPC分类号： G01N33/5695 ,  A61K39/00 ,  A61K39/04 ,  A61K2039/53 ,  C07K14/35 ,  G01N2469/20

摘要： The present invention provides transcriptionally active Mtb polynucleotides, recombinant Mtb peptides and polypeptides, and immunogenic Mtb antigens. Immunogenic compositions are also provided that may be useful as recombinant, subunit and DNA vaccines. In addition the invention provides diagnostic kits for Mtb.

摘要翻译： 本发明提供转录活性Mtb多核苷酸，重组Mtb肽和多肽，以及免疫原性Mtb抗原。 还提供可用作重组，亚单位和DNA疫苗的免疫原性组合物。 此外，本发明提供了用于Mtb的诊断试剂盒。

公开(公告)号：US20080059361A1

公开(公告)日：2008-03-06

申请号：US11933080

申请日：2007-10-31

申请人： David Roth ,  Dylan Salisbury

发明人： David Roth ,  Dylan Salisbury

IPC分类号： G06Q40/00 ,  G06F17/30 ,  G06F17/40

CPC分类号： G06Q30/08 ,  G06Q30/02 ,  G06Q30/0273 ,  G06Q40/04

摘要： A method implemented in a computer system for determining an advertisement in response to an advertising opportunity, wherein the advertising opportunity is an opportunity to place the advertisement on a web page subsequent to a request for the web page by a browser. The computer system receives an indication of the advertising opportunity, and in response to receiving the indication, the computer system determines bids, wherein each bid is associated with an advertisement, selects one of the bids and places the advertisement associated with the selected bid on the web page.

公开(公告)号：US20070102853A1

公开(公告)日：2007-05-10

申请号：US11617052

申请日：2006-12-28

申请人： David Roth

发明人： David Roth

IPC分类号： C21D1/62

CPC分类号： C21B3/06 ,  C21B2400/022 ,  C21D1/62 ,  C22B7/004 ,  C22B7/04 ,  C22B21/0069 ,  F27D3/12 ,  F27D15/02 ,  Y02P10/212 ,  Y02W30/543

摘要： A cooling head for cooling material recovered from an industrial process when the material is disposed in a material container. The cooling head includes a downwardly projecting portion that is shaped to engage the material. A plurality of ribs may extend across a top of the cooling head.

摘要翻译： 当材料设置在材料容器中时，用于从工业过程中回收的用于冷却材料的冷却头。 冷却头包括成形为接合材料的向下突出的部分。 多个肋可延伸穿过冷却头的顶部。

公开(公告)号：US07144000B2

公开(公告)日：2006-12-05

申请号：US11141657

申请日：2005-05-31

申请人： David Roth ,  James J. Dehn ,  Thomas G. Guntly

发明人： David Roth ,  James J. Dehn ,  Thomas G. Guntly

IPC分类号： F02M1/10

CPC分类号： F02M1/02 ,  F02M1/10

摘要： An internal combustion engine including a carburetor. The internal combustion engine includes a choke valve disposed within the carburetor, and a choke lever interconnected with the choke valve for movement with the choke valve. The engine also includes a throttle valve disposed within the carburetor and a throttle lever interconnected with the throttle valve for movement therewith. An intermediate lever is disposed between the throttle lever and the choke lever for movement with the choke and throttle levers. In one embodiment, the engine includes a connecting link coupled between the choke and intermediate levers, the connecting link movable with movement of the choke lever such that movement of the choke lever is translated into movement of the intermediate lever.

公开(公告)号：US20060095532A1

公开(公告)日：2006-05-04

申请号：US11285048

申请日：2005-11-22

申请人： Bret O'Rourke ,  Dawson Dean ,  Chih-Kan Wang ,  Mark Van Antwerp ,  David Roth ,  Chadd Knowlton

发明人： Bret O'Rourke ,  Dawson Dean ,  Chih-Kan Wang ,  Mark Van Antwerp ,  David Roth ,  Chadd Knowlton

IPC分类号： G06F15/167

CPC分类号： H04L29/06 ,  H04L67/2852 ,  H04L69/329

摘要： A cache server includes a media serving engine that is capable of distributing media content. A cache engine is coupled to the media serving engine and capable of caching media content. A set of cache policies is accessible by the cache engine to define the operation of the cache engine. The cache server can be configured to operate as either a cache server or an origin server. The cache server also includes a data communication interface coupled to the cache engine and the media serving engine to allow the cache engine to receive media content across a network and to allow the media serving engine to distribute media content across the network. The cache policies include policies for distributing media content from the media server, policies for handling cache misses, and policies for prefetching media content.

公开(公告)号：US20060043621A1

公开(公告)日：2006-03-02

申请号：US11141657

申请日：2005-05-31

申请人： David Roth ,  James Dehn ,  Thomas Guntly

发明人： David Roth ,  James Dehn ,  Thomas Guntly

IPC分类号： F02M1/02 ,  F02M1/10

CPC分类号： F02M1/02 ,  F02M1/10

摘要： An internal combustion engine including a carburetor. The internal combustion engine includes a choke valve disposed within the carburetor, and a choke lever interconnected with the choke valve for movement with the choke valve. The engine also includes a throttle valve disposed within the carburetor and a throttle lever interconnected with the throttle valve for movement therewith. An intermediate lever is disposed between the throttle lever and the choke lever for movement with the choke and throttle levers. In one embodiment, the engine includes a connecting link coupled between the choke and intermediate levers, the connecting link movable with movement of the choke lever such that movement of the choke lever is translated into movement of the intermediate lever.

摘要翻译： 包括化油器的内燃机。 内燃机包括设置在化油器内的阻塞阀，以及与阻流阀互连的阻塞杆，用于与阻流阀一起移动。 发动机还包括设置在化油器内的节流阀和与节流阀互连以与其一起运动的油门杆。 中间杠杆设置在节流杆和阻风杆之间，用于与扼流器和节流杆一起运动。 在一个实施例中，发动机包括联接在扼流圈和中间杆之间的连接连杆，该连接连杆可随扼流杆的运动而移动，使得阻流杆的运动转换成中间杆的运动。