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1.发明授权Antibody modulating the differentiation and function of dendritic cells via binding intercellular adhesion molecule-1 and use thereof 有权通过结合细胞间粘附分子-1调节树突状细胞的分化和功能的抗体及其用途公开(公告)号：US09115198B2
公开(公告)日：2015-08-25
申请号：US13684160
申请日：2012-11-22
Applicant: DINONA INC.
Inventor： Seong-Hoe Park , Kyeong-Cheon Jung , Youngmee Bae , Seong-Pyo Park , Yoon-Kyung Jeon
IPC: C07K16/28
CPC classification number: C07K16/2821
Abstract: The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and prolong the graft survival. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.
Abstract translation: 本发明涉及结合人细胞间粘附分子-1（ICAM-1）的抗体，其中抗体能够调节树突状细胞的分化状态并延长移植物存活。 此外，本发明提供了包含该抗体的药物组合物及其用于治疗疾病的方法。
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Patent Agency Ranking
2.发明授权Acute leukemia and lymphoblastic lymphoma-specific CD43 epitope and use thereof 有权急性白血病和淋巴细胞淋巴瘤特异性CD43表位及其用途公开(公告)号：US08753636B2
公开(公告)日：2014-06-17
申请号：US13842942
申请日：2013-03-15
Applicant: Dinona Inc.
Inventor： Seong-Hoe Park , Kyeong-Cheon Jung , Eun-Young Choi , Seong-Pyo Park
IPC: A61K39/395
CPC classification number: C07K16/3061 , A61K47/6815 , A61K47/6829 , A61K47/6849 , A61K47/6898 , A61K49/0021 , A61K49/0043 , A61K49/0058 , A61K51/1027 , B82Y5/00 , C07K14/70596 , C07K16/2896 , C07K2317/34 , Y10S435/81
Abstract: The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.
Abstract translation: 本发明涉及在人急性白血病和淋巴细胞淋巴瘤细胞上表达的CD43表位及其用途。 更具体地说，本发明涉及在人急性白血病，淋巴细胞淋巴瘤细胞上表达但不在成熟造血细胞，造血干细胞和非造血细胞上表达的CD43表位以及其在急性白血病和淋巴母细胞淋巴瘤上的诊断和治疗应用 。
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公开(公告)号：US09746474B2
公开(公告)日：2017-08-29
申请号：US14269018
申请日：2014-05-02
Applicant: DINONA INC.
Inventor： Seong-Hoe Park , Kyeong-Cheon Jung , Eun-Young Choi , Seong-Pyo Park
IPC: G01N33/574 , A61K47/48 , A61K49/00 , A61K51/10 , B82Y5/00 , C07K14/705 , C07K16/28
CPC classification number: G01N33/57426 , A61K47/6815 , A61K47/6829 , A61K47/6849 , A61K47/6898 , A61K49/0021 , A61K49/0043 , A61K49/0058 , A61K51/1027 , B82Y5/00 , C07K14/70596 , C07K16/2896 , C07K2317/34 , G01N2333/70596
Abstract: The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.
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4.发明申请Acute Leukemia And Lymphoblastic Lymphoma-Specific CD43 Epitope and Use Thereof 审中-公开急性白血病和淋巴细胞淋巴瘤特异性CD43表位及其用途公开(公告)号：US20140342374A1
公开(公告)日：2014-11-20
申请号：US14269018
申请日：2014-05-02
Applicant: Dinona Inc.
Inventor： Seong-Hoe Park , Kyeong-Cheon Jung , Eun-Young Choi , Seong-Pyo Park
IPC: G01N33/574
CPC classification number: G01N33/57426 , A61K47/6815 , A61K47/6829 , A61K47/6849 , A61K47/6898 , A61K49/0021 , A61K49/0043 , A61K49/0058 , A61K51/1027 , B82Y5/00 , C07K14/70596 , C07K16/2896 , C07K2317/34 , G01N2333/70596
Abstract: The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.
Abstract translation: 本发明涉及在人急性白血病和淋巴细胞淋巴瘤细胞上表达的CD43表位及其用途。 更具体地说，本发明涉及在人急性白血病，淋巴细胞淋巴瘤细胞上表达但不在成熟造血细胞，造血干细胞和非造血细胞上表达的CD43表位以及其在急性白血病和淋巴母细胞淋巴瘤上的诊断和治疗应用 。
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5.发明申请Acute Leukemia And Lymphoblastic Lymphoma-Specific CD43 Epitope and Use Thereof 有权急性白血病和淋巴细胞淋巴瘤特异性CD43表位及其用途公开(公告)号：US20130287683A1
公开(公告)日：2013-10-31
申请号：US13842942
申请日：2013-03-15
Applicant: DINONA INC.
Inventor： Seong-Hoe Park , Kyeong-Cheon Jung , Eun-Young Choi , Seong-Pyo Park
IPC: C07K16/30
CPC classification number: C07K16/3061 , A61K47/6815 , A61K47/6829 , A61K47/6849 , A61K47/6898 , A61K49/0021 , A61K49/0043 , A61K49/0058 , A61K51/1027 , B82Y5/00 , C07K14/70596 , C07K16/2896 , C07K2317/34 , Y10S435/81
Abstract: The present invention relates to a CD43 epitope expressed on human acute leukemia and lymphoblastic lymphoma cells and its use. More particularly, the present invention relates to a CD43 epitope expressed on human acute leukemia, lymphoblastic lymphoma cells, but not on mature hematopoietic cells, hematopoietic stem cells and non-hematopoietic cells, and to its diagnostic and therapeutic application on acute leukemia and lymphoblastic lymphoma.
Abstract translation: 本发明涉及在人急性白血病和淋巴细胞淋巴瘤细胞上表达的CD43表位及其用途。 更具体地说，本发明涉及在人急性白血病，淋巴细胞淋巴瘤细胞上表达但不在成熟造血细胞，造血干细胞和非造血细胞上表达的CD43表位以及其在急性白血病和淋巴母细胞淋巴瘤上的诊断和治疗应用 。
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6.发明申请Antibody Modulating The Differentiation And Function Of Dendritic Cells Via Binding Intercellular Adhesion Molecule-1 And Use Thereof 审中-公开抗体通过结合细胞间粘附分子-1调节树突状细胞的分化和功能及其用途公开(公告)号：US20130142811A1
公开(公告)日：2013-06-06
申请号：US13684160
申请日：2012-11-22
Applicant: Dinona Inc.
Inventor： Seong-Hoe Park , Kyeong-Cheon Jung , Youngmee Bae , Seong-Pyo Park , Yoon-Kyung Jeon
IPC: C07K16/28
CPC classification number: C07K16/2821
Abstract: The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and prolong the graft survival. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.
Abstract translation: 本发明涉及结合人细胞间粘附分子-1（ICAM-1）的抗体，其中抗体能够调节树突状细胞的分化状态并延长移植物存活。 此外，本发明提供了包含该抗体的药物组合物及其用于治疗疾病的方法。
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