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1.发明授权Antibody modulating the differentiation and function of dendritic cells via binding intercellular adhesion molecule-1 and use thereof 有权通过结合细胞间粘附分子-1调节树突状细胞的分化和功能的抗体及其用途公开(公告)号：US09115198B2
公开(公告)日：2015-08-25
申请号：US13684160
申请日：2012-11-22
Applicant: DINONA INC.
Inventor： Seong-Hoe Park , Kyeong-Cheon Jung , Youngmee Bae , Seong-Pyo Park , Yoon-Kyung Jeon
IPC: C07K16/28
CPC classification number: C07K16/2821
Abstract: The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and prolong the graft survival. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.
Abstract translation: 本发明涉及结合人细胞间粘附分子-1（ICAM-1）的抗体，其中抗体能够调节树突状细胞的分化状态并延长移植物存活。 此外，本发明提供了包含该抗体的药物组合物及其用于治疗疾病的方法。
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2.发明申请Antibody Modulating The Differentiation And Function Of Dendritic Cells Via Binding Intercellular Adhesion Molecule-1 And Use Thereof 审中-公开抗体通过结合细胞间粘附分子-1调节树突状细胞的分化和功能及其用途公开(公告)号：US20130142811A1
公开(公告)日：2013-06-06
申请号：US13684160
申请日：2012-11-22
Applicant: Dinona Inc.
Inventor： Seong-Hoe Park , Kyeong-Cheon Jung , Youngmee Bae , Seong-Pyo Park , Yoon-Kyung Jeon
IPC: C07K16/28
CPC classification number: C07K16/2821
Abstract: The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and prolong the graft survival. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.
Abstract translation: 本发明涉及结合人细胞间粘附分子-1（ICAM-1）的抗体，其中抗体能够调节树突状细胞的分化状态并延长移植物存活。 此外，本发明提供了包含该抗体的药物组合物及其用于治疗疾病的方法。
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