Invention Grant
US09115198B2 Antibody modulating the differentiation and function of dendritic cells via binding intercellular adhesion molecule-1 and use thereof
有权
通过结合细胞间粘附分子-1调节树突状细胞的分化和功能的抗体及其用途
- Patent Title: Antibody modulating the differentiation and function of dendritic cells via binding intercellular adhesion molecule-1 and use thereof
- Patent Title (中): 通过结合细胞间粘附分子-1调节树突状细胞的分化和功能的抗体及其用途
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Application No.: US13684160Application Date: 2012-11-22
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Publication No.: US09115198B2Publication Date: 2015-08-25
- Inventor: Seong-Hoe Park , Kyeong-Cheon Jung , Youngmee Bae , Seong-Pyo Park , Yoon-Kyung Jeon
- Applicant: DINONA INC.
- Applicant Address: KR Seoul
- Assignee: Dinona Inc.
- Current Assignee: Dinona Inc.
- Current Assignee Address: KR Seoul
- Agency: Alston & Bird LLP
- Main IPC: C07K16/28
- IPC: C07K16/28
Abstract:
The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and prolong the graft survival. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.
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