公开(公告)号：US20090077975A1

公开(公告)日：2009-03-26

申请号：US11918608

申请日：2006-04-18

申请人： Christian Scholz ,  Andreas Heilos ,  Stefan Hoffmann

发明人： Christian Scholz ,  Andreas Heilos ,  Stefan Hoffmann

IPC分类号： F23M5/00

CPC分类号： F27D1/04 ,  F23R3/005 ,  F23R2900/00005 ,  F27D1/0006 ,  F27D1/14

摘要： The invention relates to a heat shield element for lining a combustion chamber wall, to a combustion chamber and to a gas turbine. The heat shield element comprises a hot side that can be exposed to a hot medium, a wall side opposite said hot side, and a peripheral side adjoining the hot side and the wall side and having a peripheral side surface. Relief slots are introduced into the material in an area of the heat shield element that is susceptible to material cracks induced by thermal stress, thereby limiting crack propagation.

摘要翻译： 本发明涉及一种用于将燃烧室壁，燃烧室和燃气轮机衬套的隔热元件。 隔热元件包括可以暴露于热介质的热侧，与热侧相对的壁面和与热侧和壁侧相邻并具有周边侧表面的周边。 在隔热元件的易受热应力引起的材料裂纹敏感的区域中的材料中引入浮雕槽，从而限制裂纹扩展。

公开(公告)号：US07942007B2

公开(公告)日：2011-05-17

申请号：US11918608

申请日：2006-04-18

申请人： Christian Scholz ,  Andreas Heilos ,  Stefan Hoffmann

发明人： Christian Scholz ,  Andreas Heilos ,  Stefan Hoffmann

IPC分类号： F02C1/00

CPC分类号： F27D1/04 ,  F23R3/005 ,  F23R2900/00005 ,  F27D1/0006 ,  F27D1/14

摘要： The invention relates to a heat shield element for lining a combustion chamber wall, to a combustion chamber and to a gas turbine. The heat shield element comprises a hot side that can be exposed to a hot medium, a wall side opposite said hot side, and a peripheral side adjoining the hot side and the wall side and having a peripheral side surface. Relief slots are introduced into the material in an area of the heat shield element that is susceptible to material cracks induced by thermal stress, thereby limiting crack propagation.

摘要翻译： 本发明涉及一种用于将燃烧室壁，燃烧室和燃气轮机衬套的隔热元件。 隔热元件包括可以暴露于热介质的热侧，与热侧相对的壁面和与热侧和壁侧相邻并具有周边侧表面的周边。 在隔热元件的易受热应力引起的材料裂纹敏感的区域中的材料中引入浮雕槽，从而限制裂纹扩展。

公开(公告)号：US09604075B2

公开(公告)日：2017-03-28

申请号：US13684463

申请日：2012-11-23

申请人： Christian Scholz

发明人： Christian Scholz

IPC分类号： A61N5/10

CPC分类号： A61N5/1031 ,  A61N5/1047

摘要： A method for calculating local part radiation doses in a radiotherapy system for applying a total radiation dose in a target volume with several beams is provided. The method includes determining at least one first control plane for controlling the dosing of the beams, determining at least one second control plane for controlling the positioning of the beams, and allocating beams to the first and second control planes. The method also includes, for at least one side of a first control plane, calculating in isolation of the corresponding local part radiation doses of all the beams allocated to the first control plane.

公开(公告)号：US08790659B2

公开(公告)日：2014-07-29

申请号：US13569353

申请日：2012-08-08

申请人： Christian Scholz ,  Elke Faatz ,  Urban Schmitt ,  Peter Schaarschmidt

发明人： Christian Scholz ,  Elke Faatz ,  Urban Schmitt ,  Peter Schaarschmidt

IPC分类号： A61K39/245

CPC分类号： C12N15/62 ,  C12N9/90 ,  G01N33/536 ,  G01N33/54393 ,  Y02A50/57

摘要： Disclosed are a recombinant DNA molecule encoding a fusion protein comprising a SlpA chaperone and a target polypeptide wherein human FK506 binding proteins (FKBPs) are excluded as target polypeptides, a corresponding expression vector encoding said fusion protein as well as host cells transformed with said expression vector. Also disclosed are a method for producing the fusion protein, a recombinantly produced fusion protein comprising a SlpA chaperone and a target polypeptide. A further aspect of the invention is the use of the recombinantly produced fusion protein, and a reagent kit containing a recombinantly produced fusion protein comprising a SlpA chaperone and a target polypeptide.

摘要翻译： 公开了编码包含SlpA伴侣和靶多肽的融合蛋白的重组DNA分子，其中人FK506结合蛋白（FKBP）被排除为靶多肽，编码所述融合蛋白的相应表达载体以及用所述表达载体转化的宿主细胞 。 还公开了产生融合蛋白的方法，重组产生的包含SlpA伴侣和靶多肽的融合蛋白。 本发明的另一方面是使用重组产生的融合蛋白，以及含有重组产生的包含SlpA伴侣和靶多肽的融合蛋白的试剂盒。

公开(公告)号：US08541518B2

公开(公告)日：2013-09-24

申请号：US12920143

申请日：2009-02-10

申请人： Gerhard Albrecht ,  Klaus Lorenz ,  Christian Scholz ,  Petra Wagner

发明人： Gerhard Albrecht ,  Klaus Lorenz ,  Christian Scholz ,  Petra Wagner

IPC分类号： C08F2/04 ,  C08F224/00 ,  C08F2/10 ,  C04B28/28

CPC分类号： C08F220/04 ,  C08F220/26

摘要： A process for the preparation of a copolymer in a semicontinuous mode of operation in a polymerization apparatus containing a polymerization reactor connected to a metering device, in each case acid monomer being initially introduced into the metering device and polyether macromonomer and water into the polymerization reactor, acid monomer being metered from the metering device into the polymerization reactor, the metering of the acid monomer into the polymerization reactor being effected in such a way that first a polymerization pH is established in the aqueous medium and then, until the conversion of 70 mol % of the polyether macromonomer initially introduced into the polymerization reactor, acid monomer is passed into the polymerization reactor in an amount per unit time such that the pH in the aqueous medium deviates by not more than ±0.3 from the initially established polymerization pH.

摘要翻译： 在含有连接到计量装置的聚合反应器的聚合装置中制备半连续操作模式的共聚物的方法，每种情况下，酸性单体最初引入计量装置和聚醚大分子单体和水进入聚合反应器， 酸性单体从计量装置计量到聚合反应器中，酸性单体计量到聚合反应器中的方式是首先在水性介质中建立聚合pH，然后直到70mol％ 的最初引入聚合反应器的聚醚大分子单体，酸单体以每单位时间的量进入聚合反应器，使得水介质中的pH从最初建立的聚合pH偏离不大于±0.3。

公开(公告)号：US08536251B2

公开(公告)日：2013-09-17

申请号：US13132990

申请日：2009-11-25

申请人： Silke Flakus ,  Klaus Lorenz ,  Helmut Mack ,  Christian Scholz ,  Petra Wagner ,  Barbara Wimmer ,  Angelika Hartl ,  Martin Winklbauer ,  Manfred Bichler

发明人： Silke Flakus ,  Klaus Lorenz ,  Helmut Mack ,  Christian Scholz ,  Petra Wagner ,  Barbara Wimmer ,  Angelika Hartl ,  Martin Winklbauer ,  Manfred Bichler

IPC分类号： C04B24/26 ,  C08L53/00 ,  C08L39/04 ,  C08L27/04 ,  C08L29/00 ,  C08K5/00 ,  C08F16/12 ,  C08F220/12 ,  C08F12/30 ,  C08F30/02

CPC分类号： C08F216/1416 ,  C04B24/2605 ,  C04B24/2647 ,  C04B24/267 ,  C04B28/02 ,  C04B28/04 ,  C04B2103/30 ,  C04B2103/408 ,  C08F220/06 ,  C04B14/06

摘要： The invention relates to a copolymer comprising i) 3 to 40 mol % of an isoprenolpolyether derivative structural unit α ii) 3 to 40 mol % of a vinyloxypolyether derivative structural unit β and iii) 35 to 93 mol % of an acid structural unit γ, the structural units of the copolymer which belong to the vinyloxypolyether derivative structural unit β having longer side chains than the structural units which belong to the isoprenolpolyether derivative structural unit α.

摘要翻译： 本发明涉及一种共聚物，其包含i）3至40mol％的异戊二烯聚醚衍生物结构单元αii）3至40mol％的乙烯氧基聚醚衍生物结构单元β和iii）35至93mol％的酸性结构单元γ， 属于乙烯氧基聚醚醚衍生物结构单元β的共聚物的结构单元具有比属于异戊二烯聚醚衍生物结构单元α的结构单元更长的侧链。

公开(公告)号：US20130079579A1

公开(公告)日：2013-03-28

申请号：US13627734

申请日：2012-09-26

申请人： Mark Hastenteufel ,  Iwan Kawrakow ,  Christian Scholz

发明人： Mark Hastenteufel ,  Iwan Kawrakow ,  Christian Scholz

IPC分类号： A61N5/10

CPC分类号： A61N5/10 ,  A61N5/1031 ,  A61N5/1065 ,  A61N2005/1061 ,  A61N2005/1074 ,  A61N2005/1087

摘要： A method and a device for regulating a therapeutic beam directed at an object are provided. The method includes displaying at least one multidimensional image data record encompassing at least one target area of the object. The method also includes determining the treatment beam dosage directed at the at lest one target area, and recording and optionally visualizing an isoline or isosurface dependent on the treatment beam dosage in the at least one multidimensional image data record. The method includes adjusting the isoline or isosurface such that the isoline or isosurface approximates a contour of the target area as closely as possible or corresponds to the contour, and regulating the treatment beam dosage by evaluation of the adjusted isoline or isosurface.

摘要翻译： 提供了一种用于调节针对物体的治疗束的方法和装置。 该方法包括显示包含对象的至少一个目标区域的至少一个多维图像数据记录。 该方法还包括确定针对最少一个目标区域的治疗束剂量，以及取决于至少一个多维图像数据记录中的治疗束剂量的记录和任选地显现等值线或等值面。 该方法包括调整等值线或等值面，使得等值线或等值面近似于目标区域的轮廓尽可能接近或对应于轮廓，并且通过评估调整的等值线或等值面来调节治疗束的剂量。

公开(公告)号：US07604935B2

公开(公告)日：2009-10-20

申请号：US11584887

申请日：2006-10-23

申请人： Barbara Upmeier ,  Ralf Bollhagen ,  Alfred Engel ,  Elke Faatz ,  Peter Schaarschmidt ,  Christian Scholz ,  Toralf Zarnt

发明人： Barbara Upmeier ,  Ralf Bollhagen ,  Alfred Engel ,  Elke Faatz ,  Peter Schaarschmidt ,  Christian Scholz ,  Toralf Zarnt

IPC分类号： C12Q1/70 ,  C12N7/01 ,  A61K39/20

CPC分类号： C07K14/005 ,  C07K2319/35 ,  C12N2770/36222 ,  Y10S530/826

摘要： A soluble rubella E1 antigen variant is disclosed that comprises amino acids 334-409 of the native rubella E1 peptide, but lacks the C-terminal end and at least the transmembrane region and the anchor segment as well as at least the amino acids 143 to 164. Also described is a recombinant DNA molecule encoding the rubella E1 antigen variants which are recombinantly expressed as a chaperone fusion protein, refolded into a soluble and immunoreactive conformation, and further used for the serological detection of anti-rubella antibodies. In addition, also disclosed is a method for the detection, determination and quantification of anti-rubella antibodies of IgG and/or IgM subclass in a sample wherein the rubella E1 antigen is used as a capture reagent and/or binding partner for the antibodies.

摘要翻译： 公开了可溶性风疹E1抗原变体，其包含天然风疹E1肽的氨基酸334-409，但缺少C末端和至少跨膜区和锚定区以及至少氨基酸143至164 还描述了编码风疹E1抗原变体的重组DNA分子，其被重组表达为伴侣融合蛋白，重折叠成可溶性和免疫反应性构象，并进一步用于抗风疹抗体的血清学检测。 此外，还公开了用于检测，测定和定量样品中IgG和/或IgM亚类的抗风疹抗体的方法，其中所述风疹E1抗原用作抗体的捕获试剂和/或结合配偶体。

公开(公告)号：US07278628B2

公开(公告)日：2007-10-09

申请号：US10503561

申请日：2003-01-30

申请人： Christian Scholz

发明人： Christian Scholz

IPC分类号： B01F3/04

CPC分类号： A61L9/125 ,  Y10S261/88

摘要： Apparatus for dosing gaseous and/or vaporous substances An apparatus for dosing gaseous and/or vaporous substances, in particular for generating varying scents, includes a multitude of packaged storage containers (1) from which different gases and/or vapors are driven out by a carrier medium. On their inlet sides, the storage containers are connected to a common carrier medium manifold (13) via a shut-off device (4) assigned to each storage container that can be actuated, and on their outlet sides to a joint homogenization chamber (8). Both the carrier medium manifold and the homogenization chamber are connected to a carrier medium source using a regulating valve (5, 9). Check valves (6, 7) are integrated in the gas passages to the storage container and from the storage container to the homogenization chamber. A dosing apparatus designed based on this principle is characterized by low space requirements and materially separate volume flows that can be exactly timed and dosed.

摘要翻译： 用于计量气态和/或蒸气物质的装置用于给气体和/或蒸气物质进行投配，特别是用于产生不同气味的装置包括多个包装的储存容器（1），不同的气体和/或蒸汽从其中被 载体介质。 在其入口侧，储存容器通过分配给可以被致动的每个储存容器的切断装置（4）连接到共同的载体介质歧管（13），并且在它们的出口侧连接到接头均化室（8 ）。 载体介质歧管和均质室都使用调节阀（5,9）连接到载体介质源。 止回阀（6,7）集成在储存容器和从储存容器到匀浆室的气体通道中。 基于该原理设计的计量装置的特征在于具有低空间要求和能够精确定时和计量的物质上独立的体积流量。

公开(公告)号：US20060247402A1

公开(公告)日：2006-11-02

申请号：US10551268

申请日：2004-03-05

申请人： Toshimi Matsumoto ,  Sven Asmus ,  Gerhard Albrecht ,  Klaus Lorenz ,  Petra Wagner ,  Christian Scholz

发明人： Toshimi Matsumoto ,  Sven Asmus ,  Gerhard Albrecht ,  Klaus Lorenz ,  Petra Wagner ,  Christian Scholz

IPC分类号： C08F224/00

CPC分类号： C04B24/2647 ,  C04B24/267 ,  C04B24/2688 ,  C04B40/0039 ,  C04B2111/34 ,  C04B24/06 ,  C04B24/121 ,  C04B24/122 ,  C04B24/18 ,  C04B24/32 ,  C04B24/38 ,  C04B38/10 ,  C04B2103/10 ,  C04B2103/20 ,  C04B2103/304 ,  C04B2103/44 ,  C04B2103/50 ,  C04B2103/61

摘要： The present invention concerns a cement additive containing copolymers comprising one or more constitutional units represented by formula A: (A) R1 is hydrogen, an alkyl group having 1 to 4 carbon atoms, an alkenyl group having 1 to 4 carbon atoms or an aryl group having 6 to 9 carbon atoms; R2 is hydrogen or an alkyl group having 1 to 9 carbon atoms, an alkenyl group having 1 to 9 carbon atoms or an aryl group having 6 to 9 carbon atoms; T is alkylene (including straight-chain and branched alkylene) having 1 to 4 carbon atoms or arylene having 6 to 9 carbon atoms; n is 0 or 1; S1 and S2 are, independently of one another, —OCkH2k— or —OCH2CHR3—, with the proviso that k is 2 or 3, R3 is an alkyl group having 1 to 9 carbon atoms, an aryl group having 6 to 9 carbon atoms; and 6

摘要翻译： 本发明涉及包含一种或多种由式A表示的结构单元的共聚物的水泥添加剂：（A）R 1是氢，具有1至4个碳原子的烷基，具有1个 至4个碳原子或具有6至9个碳原子的芳基; R2是氢或碳原子数1〜9的烷基，碳原子数1〜9的烯基或碳原子数6〜9的芳基。 T是具有1至4个碳原子的亚烷基（包括直链和支链亚烷基）或具有6至9个碳原子的亚芳基; n为0或1; S 1和S 2 2彼此独立地是-OC 2 k H 2 - 或-OCH 3， 其中k为2或3，R3为碳原子数1〜9的烷基，碳原子数为6〜9的芳基。 和6 <_M 1 + m 2 <_ 25。