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公开(公告)号：US20220313200A1
公开(公告)日：2022-10-06
申请号：US17642691
申请日：2020-11-25
申请人： CHECK-CAP LTD.
发明人： Yoav KIMCHY , Ofer HAZUT , Elik CHEN
摘要： An imaging capsule, including a radiation source, a collimator that provides a collimated beam from the radiation source, a detector configured to detect particles resulting from X-ray fluorescence and/or Compton backscattering in response to the collimated beam, a motor to rotate the collimator and detector around an axle to scan a partial or full inner circumference of a user's colon with radiation, wherein the motor comprises a segmented commutator that is fed with a power signal via brush contacts; and wherein the motor provides a pulsed output signal based on mechanical switching of the segmented commutator on the brush contacts, providing an indication of the rotation angle of the motor as a function of time.
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公开(公告)号：US20210267475A1
公开(公告)日：2021-09-02
申请号：US17261580
申请日：2019-02-06
申请人： CHECK-CAP LTD.
发明人： Michael SMIRNOV , Hadas SHAHAR , Shlomo LEWKOWICZ , Alex OVADIA , Yoav KIMCHY , Boaz SHPIGELMAN
摘要： A system for polyp detection through capsule dynamics, including a capsule configured to be swallowed by a patient, a recorder configured to be worn by the patient and to receive transmission of information from the capsule, wherein the system is configured to determine position or motion information of the capsule from the information received from the capsule, analyze the position or motion information and determine a probability score representing the likelihood of the existence of polyps in the gastrointestinal tract of the patient; and wherein the system notifies the patient of further actions to be performed in response to the determined probability score.
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公开(公告)号：US20180214104A1
公开(公告)日：2018-08-02
申请号：US15505612
申请日：2015-10-12
申请人： CHECK-CAP LTD.
发明人： Yoav KIMCHY , Shlomo LEWKOWICZ
IPC分类号： A61B6/00 , A61K49/00 , G01N23/223
CPC分类号： A61B6/50 , A61B6/4057 , A61B6/4241 , A61B6/425 , A61B6/485 , A61K49/0065 , A61K49/0428 , B82Y15/00 , G01N23/223
摘要： A colon imaging system, including an imaging capsule, having: a. a radiation source providing X-Ray and gamma radiation with energies sufficient to induce X-Ray fluorescence from nanoparticles that adhere to cancerous tissue, and which were administered to a patient in a solution prior to examining the colon with the imaging capsule; b. a detector for detecting particle energy of particles emitted responsive to the provided radiation and forming count information disclosing a number of particles detected for each energy level; c. a transceiver for transferring the count information to an external computer for analysis, and also having a computer for constructing images of an inside of the colon based on the count information; wherein the images provide an indication of locations in the colon of which the nanoparticles adhere to.
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公开(公告)号：US20160228077A1
公开(公告)日：2016-08-11
申请号：US15025895
申请日：2014-11-18
申请人： CHECK-CAP LTD.
发明人： Yoav KIMCHY , Shai BRENNER
CPC分类号： A61B6/4057 , A61B1/041 , A61B5/065 , A61B6/06 , A61B6/107 , A61B6/425 , A61B6/4258 , A61B6/4476 , A61B6/481 , A61B6/482 , A61B6/483 , A61B6/485 , A61B6/54 , A61B6/542 , A61B6/547 , A61B6/56 , A61B2562/162
摘要： A fail safe concealment mechanism for a radiation imaging capsule, including, a collimator having a first area that blocks radiation and an second area that releases radiation, a radiation source that is initially positioned inside the collimator in the area that blocks radiation, a linear mechanism that moves the radiation source inside the collimator to the area that releases radiation when power is provided to the mechanism and automatically returns the radiation source to the area that blocks radiation when power is not provided to the mechanism.
摘要翻译： 一种用于放射线成像胶囊的故障安全隐藏机构，包括具有阻挡辐射的第一区域的准直仪和释放辐射的第二区域，最初位于准直仪内部的阻挡辐射的区域内的辐射源;线性机构 当将功率提供给机构时，将准直器内部的辐射源移动到释放辐射的区域，并且当不向机构供电时，将辐射源自动地返回到阻挡辐射的区域。
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公开(公告)号：US20160066813A1
公开(公告)日：2016-03-10
申请号：US14785860
申请日：2014-05-05
申请人： CHECK-CAP LTD.
发明人： Yoav KIMCHY , Boris KARELIN , Boaz SHPIGELMAN , Alex OVADIA
CPC分类号： A61B5/062 , A61B1/00004 , A61B1/00016 , A61B1/0002 , A61B1/041 , A61B1/045 , A61B5/073 , A61B5/6833 , A61B5/7203 , A61B5/725 , A61B2562/0219 , A61B2562/0223 , A61B2562/162
摘要： A system for estimating the position of an imaging capsule that examines the gastrointestinal tract of a user, including an imaging capsule for examining inside the user; and a recorder for communicating with the imaging capsule from outside the user. The imaging capsule includes a controller for controlling functionality of the imaging capsule, a transceiver for communication with the recorder and a coil for transmission of electromagnetic signals. The recorder includes a controller for controlling functionality of the recorder, a transceiver for communication with the imaging capsule and a coil for receiving electromagnetic signals from the coil of the imaging capsule. Wherein the recorder determines the location of the imaging capsule based on measurements of the amplitude of the electromagnetic signals transmitted by the coil in the imaging capsule.
摘要翻译： 一种用于估计检查用户的胃肠道的成像胶囊的位置的系统，包括用于在使用者内检查的成像胶囊; 以及用于从用户外部与成像胶囊通信的记录器。 成像胶囊包括用于控制成像胶囊的功能的控制器，用于与记录器通信的收发器和用于传输电磁信号的线圈。 记录器包括用于控制记录器的功能的控制器，用于与成像胶囊通信的收发器和用于从成像胶囊的线圈接收电磁信号的线圈。 其中记录器基于由成像胶囊中的线圈传输的电磁信号的幅度的测量值确定成像胶囊的位置。
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公开(公告)号：US20140275782A1
公开(公告)日：2014-09-18
申请号：US14218961
申请日：2014-03-18
申请人： CHECK CAP LTD.
发明人： Yoav KIMCHY
CPC分类号： A61B1/00029 , A61B1/041 , A61B1/043 , A61B1/31
摘要： An imaging capsule activating system includes a capsule containing a radiation source and an arrangement with the radiation source mounted thereon. The arrangement is configured to selectively allow emission of radiation from the radiation source. A blocking arrangement is configured to selectively block emission of radian from the radiation source. In a rest position, the emission of radiation from the arrangement is blocked. A movement arrangement configured to move the blocking arrangement relative to the arrangement. A controller operates the radiation source and the blocking arrangement. An activation coil is electrically coupled with the controller and has an initial configuration without current flow. An external activating coil receives the imaging capsule and is operable to inductively induce current flow in the activation coil within the capsule.
摘要翻译： 成像胶囊激活系统包括包含辐射源的胶囊和其上安装有辐射源的装置。 该布置被配置为选择性地允许从辐射源发射辐射。 阻挡装置被配置为选择性地阻挡辐射源的辐射发射。 在静止位置，来自该装置的辐射的发射被阻挡。 一种配置成相对于该装置移动该阻挡装置的移动装置。 控制器操作辐射源和阻塞装置。 激活线圈与控制器电耦合并且具有没有电流的初始配置。 外部激活线圈接收成像胶囊并且可操作地感应地感应胶囊内的激活线圈中的电流。
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公开(公告)号：US20200214636A1
公开(公告)日：2020-07-09
申请号：US16627367
申请日：2018-06-07
申请人： CHECK-CAP LTD.
发明人： Yoav KIMCHY , Shlomo LEWKOWIZ , Sigalit KIMCHY
摘要： A capsule for traversing the gastrointestinal tract, including one or more compartments configured to sample the environment surrounding the capsule or configured to deliver content to the environment surrounding the capsule, an internal controller configured to activate the one or more compartments to sample or deliver, wherein the capsule includes a tracking system configured to identify the location of the capsule in real-time and activate a compartment when reaching a specific location in the gastrointestinal tract.
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公开(公告)号：US20190213760A1
公开(公告)日：2019-07-11
申请号：US16311690
申请日：2017-07-31
申请人： CHECK-CAP LTD.
发明人： Daniel RUBIN , Ronen LIFSHITZ , Yoav KIMCHY
摘要： A method of reconstructing an image of a colon, including receiving scan data of a colon taken by an imaging capsule that traverses the colon; wherein the imaging capsule emits X-ray radiation inside the colon and includes detectors that detect photons that are returned toward the imaging capsule from X-ray fluorescence and Compton back scattering interactions responsive to the radiation; and wherein the scan data includes counts of photons detected by each detector from X-ray fluorescence and Compton back scattering interactions; defining an initial guess of a geometry of a contour of a slice of the colon; calculating count values for each detector responsive to the geometry using a forward model; comparing the calculated count values of each detector with the values from the scan data; if the results of the comparison do not indicate reaching an optimal match then adjust the defined geometry and repeat the calculating and comparing.
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公开(公告)号：US20180153497A1
公开(公告)日：2018-06-07
申请号：US15572790
申请日：2016-05-01
申请人： CHECK-CAP LTD.
发明人： Dmitry GUBICH , Avner ELGALI , Yoav KIMCHY
CPC分类号： A61B6/541 , A61B1/00147 , A61B1/041 , A61B1/043 , A61B1/2736 , A61B5/036 , A61B5/065 , A61B5/066 , A61B5/073 , A61B6/4057 , A61B6/4258 , A61B6/4405 , A61B6/4417 , A61B6/4452 , A61B6/50 , A61B6/56
摘要： An imaging capsule configured to be swallowed to scan the gastrointestinal tract of a person from the inside, including a radiation source providing X-Ray and gamma radiation for scanning the gastrointestinal tract, a pressure sensor for measuring the internal pressure in the imaging capsule; and wherein the imaging capsule is configured to control the emission of radiation from within the imaging capsule responsive to the measurements of the pressure sensor.
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公开(公告)号：US20160324492A1
公开(公告)日：2016-11-10
申请号：US15110946
申请日：2014-04-08
申请人： CHECK-CAP LTD.
发明人： Yoav KIMCHY , Salah HASOON
CPC分类号： A61B6/425 , A61B1/041 , A61B6/4057 , A61K51/1262
摘要： A method of preparing a radioactive material to serve as a radiation source for an intra-lumen imaging capsule, including, receiving a radioactive substance having grains in powder form, forming a solid pellet wherein the grains of the radioactive substance are dispersed homogenously in the pellet and surrounded by less dense materials having lower radiation absorption.
摘要翻译： 一种制备用作腔内成像胶囊的辐射源的放射性物质的方法，包括：接收具有粉末状颗粒的放射性物质，形成固体颗粒，其中所述放射性物质的颗粒均匀地分散在颗粒中 并被具有较低辐射吸收的较不致密的材料包围。
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