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公开(公告)号:US20230272555A1
公开(公告)日:2023-08-31
申请号:US18315532
申请日:2023-05-11
发明人: Kwang-Hyun BAEK , So-Ra KIM , Seul-Ki KWON , Soo-Yeon KIM , Da-Hye LEE
摘要: Provided is a vector library for yeast two-hybrid screening of a deubiquitinating enzyme that binds to a target protein and a method for identifying a deubiquitinating enzyme binding to a target protein using the same. Further provided is a method for screening an agent having anti-cancer activity targeting the deubiquitinating enzyme USP1, USP7, USP12, or USP49 identified by the identifying method.
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公开(公告)号:US20210032619A1
公开(公告)日:2021-02-04
申请号:US16636523
申请日:2018-08-06
发明人: Kwang-Hyun BAEK , So-Ra KIM , Seul-Ki KWON , Soo-Yeon KIM , Da-Hye LEE
摘要: The present invention provides a vector library for yeast two-hybrid screening of a deubiquitinating enzyme that binds to a target protein and a method for identifying a deubiquitinating enzyme binding to a target protein using the same. Also, the present invention provides a method for screening an agent having anti-cancer activity targeting the deubiquitinating enzyme USP1, USP7, USP12, or USP49 identified by said identifying method.
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