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公开(公告)号：US12000058B2
公开(公告)日：2024-06-04
申请号：US18169365
申请日：2023-02-15
发明人： Ozan Akkus , Mousa Younesi , Umit Levent Erol
摘要： A method for producing an electrocompacted and aligned strand is disclosed. The method includes the steps of: providing a channel having an anode on one side and a cathode on the other side separated by a non-conductive material to form an electrode; dispensing a solution comprising one or more electrocompactable and alignable molecules, nanoparticles or microparticles with ampholytic nature into the channel to complete a circuit between the anode and the cathode; applying a DC current in the range of 1-200 volts to the electrode through the solution in the channel to form an electrocompacted and aligned strand; and transferring the aligned strand out of the electrode. The one or more electrocompactable and alignable molecules, nanoparticles or microparticles with ampholytic nature can comprise collagen molecules that have different charges at different pH values. Materials including electrochemically aligned and compacted compounds are also disclosed.
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公开(公告)号：US11618961B2
公开(公告)日：2023-04-04
申请号：US16605859
申请日：2018-04-20
发明人： Ozan Akkus , Mousa Younesi , Umit Levent Erol
摘要： Devices suitable for the production of electrochemically aligned materials such as strands, threads or fibers. The device includes a substantially horizontally aligned electrochemical cell in one embodiment, with the arrangement producing highly compacted materials. Materials including electrochemically aligned and compacted compounds are also disclosed, along with methods for making and using the materials.
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3.发明申请公开(公告)号：US20180133950A1
公开(公告)日：2018-05-17
申请号：US15814997
申请日：2017-11-16
CPC分类号： B29C53/60 , A61F2/04 , A61L27/12 , A61L27/18 , A61L27/56 , A61L29/06 , A61L29/16 , A61L31/06 , A61L31/16 , B29C41/02 , B29C41/085 , B29L2023/007 , B29L2031/7532 , B29L2031/7542 , B29L2031/7546 , C08L67/04
摘要： A device suitable for constructing hollow cylindrical structures, particularly useful as medical devices. The devices are versatile in nature and can fabricate hollow cylindrical structures having single or multiple layers of one or more different materials, including biomaterials. Methods for utilizing the devices and fabricating hollow cylindrical structures are also disclosed. Fabricated hollow cylindrical structures are described herein. including embodiments incorporating a biomaterial that facilitates cell attachment and tissue integration.
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