公开(公告)号：US20070141614A1

公开(公告)日：2007-06-21

申请号：US11640066

申请日：2006-12-15

Applicant: Brajesh Singh ,  Colin Campbell

Inventor： Brajesh Singh ,  Colin Campbell

IPC: C12Q1/68

CPC classification number: C12Q1/683 ,  C12Q1/6858 ,  C12Q2563/107 ,  C12Q2545/114 ,  C12Q2537/143

Abstract: There is provided a method of nucleic acid analysis which allows analysis of genetic diversity in multiple populations to be performed rapidly and simultaneously. The method comprises (a) isolating nucleic acid from said sample; (b) providing at least two pairs of labelled primers, wherein each said primer pair is complementary to a marker sequence in a nucleic acid of at least one member; (c) amplifying the nucleic acid; (d) digesting the labelled amplified nucleic acid with at least one restriction enzyme to produce restriction fragments, and size sorting said fragments to produce a restriction fragment length profile, and (e) analysing said restriction fragment length profile so obtained; wherein the primer pairs provided for each marker have a different sequence to the sequence of the primer pairs for each other marker, and wherein each said primer pair is uniquely labelled relative to the other primer pair(s). In one embodiment each primer pair is uniquely labelled at the 5′ end with a fluorophore. The restriction fragments can be conveniently analysed by a DNA sequencer. The method of the invention has the advantage that it allows nucleic acid amplified using multiple marker sequences to be simultaneously analysed.

Abstract translation: 提供了一种核酸分析方法，其允许快速和同时地进行多个群体中遗传多样性的分析。 该方法包括（a）从所述样品中分离核酸; （b）提供至少两对标记的引物，其中每个所述引物对与至少一个成员的核酸中的标记序列互补; （c）扩增核酸; （d）用至少一种限制酶消化标记的扩增核酸以产生限制性片段，并对所述片段进行大小排序以产生限制性片段长度分布，和（e）分析如此获得的所述限制性片段长度分布; 其中为每个标记提供的引物对具有与每个其他标记的引物对的序列不同的序列，并且其中每个所述引物对相对于另一个引物对唯一地标记。 在一个实施方案中，每个引物对在5'端用荧光团唯一地标记。 限制性片段可以通过DNA测序仪方便地分析。 本发明的方法的优点是允许同时分析使用多个标记序列扩增的核酸。

公开(公告)号：US08133676B2

公开(公告)日：2012-03-13

申请号：US11640066

申请日：2006-12-15

Applicant: Brajesh Singh ,  Colin Campbell

Inventor： Brajesh Singh ,  Colin Campbell

IPC: C12P19/34

CPC classification number: C12Q1/683 ,  C12Q1/6858 ,  C12Q2563/107 ,  C12Q2545/114 ,  C12Q2537/143

Abstract: There is provided a method of nucleic acid analysis which allows analysis of genetic diversity in multiple populations to be performed rapidly and simultaneously. The method comprises (a) isolating nucleic acid from said sample; (b) providing at least two pairs of labelled primers, wherein each said primer pair is complementary to a marker sequence in a nucleic acid of at least one member; (c) amplifying the nucleic acid; (d) digesting the labelled amplified nucleic acid with at least one restriction enzyme to produce restriction fragments, and size sorting said fragments to produce a restriction fragment length profile, and (e) analysing said restriction fragment length profile so obtained; wherein the primer pairs provided for each marker have a different sequence to the sequence of the primer pairs for each other marker, and wherein each said primer pair is uniquely labelled relative to the other primer pair(s). In one embodiment each primer pair is uniquely labelled at the 5′ end with a fluorophore. The restriction fragments can be conveniently analysed by a DNA sequencer. The method of the invention has the advantage that it allows nucleic acid amplified using multiple marker sequences to be simultaneously analysed.

Abstract translation: 提供了一种核酸分析方法，其允许快速和同时地进行多个群体中遗传多样性的分析。 该方法包括（a）从所述样品中分离核酸; （b）提供至少两对标记的引物，其中每个所述引物对与至少一个成员的核酸中的标记序列互补; （c）扩增核酸; （d）用至少一种限制酶消化标记的扩增核酸以产生限制性片段，并对所述片段进行大小排序以产生限制性片段长度分布，和（e）分析如此获得的所述限制性片段长度分布; 其中为每个标记提供的引物对具有与每个其他标记的引物对的序列不同的序列，并且其中每个所述引物对相对于另一个引物对唯一地标记。 在一个实施方案中，每个引物对在5'端用荧光团唯一地标记。 限制性片段可以通过DNA测序仪方便地分析。 本发明的方法的优点是允许同时分析使用多个标记序列扩增的核酸。

公开(公告)号：US09378505B2

公开(公告)日：2016-06-28

申请号：US13190289

申请日：2011-07-25

Applicant: Blair William McNea ,  Colin Campbell ,  Steven Vanderburg

Inventor： Blair William McNea ,  Colin Campbell ,  Steven Vanderburg

IPC: G06Q30/00 ,  G06Q30/02

CPC classification number: G06Q30/016 ,  G06Q20/407 ,  G06Q30/01 ,  G06Q30/0243 ,  G06Q30/0244 ,  G06Q50/188 ,  H04L51/36 ,  H04M15/46

Abstract: Novel tools and techniques to optimize, from a merchant's perspective, the outcomes of interactions between the merchant and its customers (whether existing, new, or potential customers). In an aspect, certain embodiments allow for multiple variations of options (multivariate or A/B testing) and outcomes which can be statistically applied and then measured and analyzed for best economic impact or preferred outcome.

Abstract translation: 从商家的角度，优化商家与客户（无论是现有客户，新客户还是潜在客户）之间的互动结果的新工具和技术。 在一个方面，某些实施例允许选项（多变量或A / B测试）和结果的多种变化，其可以被统计学应用，然后测量和分析以获得最佳经济影响或优选结果。

公开(公告)号：US09170684B2

公开(公告)日：2015-10-27

申请号：US13214326

申请日：2011-08-22

Applicant: Colin Campbell ,  Hazel McInnes ,  Jeffrey Raynor ,  Mathieu Reigneau

Inventor： Colin Campbell ,  Hazel McInnes ,  Jeffrey Raynor ,  Mathieu Reigneau

IPC: G01J1/04 ,  G06F3/042 ,  G06F3/0346 ,  G06F3/03 ,  G06F1/16 ,  G06F3/0354 ,  G02B6/42 ,  G06F3/0338

CPC classification number: G06F3/0425 ,  G02B6/4214 ,  G06F1/169 ,  G06F3/0317 ,  G06F3/0338 ,  G06F3/0346 ,  G06F3/0354 ,  G06F3/03547 ,  G06F3/042 ,  G06F2203/04109

Abstract: An optical navigation device may include an image sensor with an imaging surface, a laser, and an optical waveguide layer having an exposed user surface and a total internal reflection (TIR) surface on the underside of the exposed user surface. The waveguide layer, the laser, and the image sensor may be together arranged to direct radiation emitted by the laser onto the imaging surface at least partly by total internal reflection by the TIR surface.

Abstract translation: 光学导航装置可以包括具有成像表面的图像传感器，激光器和具有暴露的使用者表面和暴露的使用者表面的下侧上的全内反射（TIR）表面的光波导层。 波导层，激光器和图像传感器可以一起布置成至少部分地通过TIR表面的全内反射将由激光器发射的辐射引导到成像表面上。

公开(公告)号：US08928893B2

公开(公告)日：2015-01-06

申请号：US13242708

申请日：2011-09-23

Applicant: Ewan Findlay ,  Colin Campbell ,  Gemma Ramsey ,  Eric Saugier

Inventor： Ewan Findlay ,  Colin Campbell ,  Gemma Ramsey ,  Eric Saugier

IPC: G01B11/14 ,  G02B27/00 ,  G01J1/44 ,  H04B10/00 ,  H04B10/08 ,  H01L31/173 ,  H01L31/12 ,  H03K17/94 ,  H01L25/16 ,  H03K17/945

CPC classification number: H03K17/941 ,  H01L25/167 ,  H01L31/125 ,  H01L31/173 ,  H01L2924/0002 ,  H03K2017/9455 ,  H03K2217/94108 ,  H01L2924/00

Abstract: The internal propagation of radiation between a radiation source and radiation detector mounted within a sensor package is prevented by the use of an optical isolator. The optical isolator is formed by the combination of a baffle mounted between the source and detector and a groove formed in an upper surface of the sensor package between the source and detector. A bottom of the groove is positioned adjacent to an upper edge of the baffle.

Abstract translation: 通过使用光隔离器来防止辐射源和安装在传感器封装内的辐射探测器之间的辐射的内部传播。 光隔离器由安装在源和检测器之间的挡板和在源和检测器之间形成在传感器封装的上表面中的凹槽的组合形成。 凹槽的底部邻近挡板的上边缘定位。

公开(公告)号：US08300332B2

公开(公告)日：2012-10-30

申请号：US12814112

申请日：2010-06-11

Applicant: Colin Campbell

Inventor： Colin Campbell

IPC: G02B7/02

CPC classification number: H01L27/14685 ,  G02B7/023 ,  G02B7/04 ,  H01L27/14618 ,  H01L27/14625 ,  H01L2924/0002 ,  H01L2924/00

Abstract: A lens mounting assembly includes a lens barrel with a first lens assembly. A lens mount includes an image sensor, and the lens barrel matingly connects with the lens mount in a manner which allows the first lens assembly to be moved along an optical axis to adjust a focus on the image sensor. A second lens assembly is provided for adjusting the focus on the image sensor during use of the lens. An alignment projection is provided on at least one of the first or second lens assemblies, the alignment projection being adapted to mate with a portion of the other of the first or second lens assemblies in order to directly optically align the first and second lens assemblies with the image sensor.

Abstract translation: 透镜安装组件包括具有第一透镜组件的透镜镜筒。 透镜座包括图像传感器，并且透镜镜筒以允许第一透镜组件沿着光轴移动以调节图像传感器上的焦点的方式与透镜座配合地连接。 提供了第二透镜组件，用于在透镜使用期间调节图像传感器上的焦点。 对准突起设置在第一或第二透镜组件中的至少一个上，对准突起适于与第一或第二透镜组件中的另一个的一部分配合，以便使第一和第二透镜组件与 图像传感器。

公开(公告)号：US20120195079A1

公开(公告)日：2012-08-02

申请号：US13018371

申请日：2011-01-31

Applicant: Ryan Kroeze ,  Colin Campbell ,  Nicholas R. Kalayjian

Inventor： Ryan Kroeze ,  Colin Campbell ,  Nicholas R. Kalayjian

IPC: H02H7/122

CPC classification number: H02M7/5387 ,  H02M1/32

Abstract: An apparatus includes an inverter including a high-side switch coupled to a low-side switch, the inverter generating a time-varying drive current from a plurality of drive control signals, a positive rail voltage, and a negative rail voltage wherein controlling the switches to generate the time-varying drive current produces a potential transitory overshoot condition for one of the switches of the inverter; a drive control, coupled to the inverter, to generate the drive control signals and to set a level of each of the rail voltages responsive to a plurality of controller signals; and a controller monitoring one or more parameters indicative of the potential transitory voltage overshoot condition, the controller dynamically adjusting, responsive to the monitored parameters, the controller signals to reduce a risk of occurrence of the potential transitory voltage overshoot condition.

公开(公告)号：US20120133956A1

公开(公告)日：2012-05-31

申请号：US13242708

申请日：2011-09-23

Applicant: Ewan Findlay ,  Colin Campbell ,  Gemma Ramsey ,  Eric Saugier

Inventor： Ewan Findlay ,  Colin Campbell ,  Gemma Ramsey ,  Eric Saugier

IPC: G01B11/14 ,  H01L31/18 ,  H01L31/0232

CPC classification number: H03K17/941 ,  H01L25/167 ,  H01L31/125 ,  H01L31/173 ,  H01L2924/0002 ,  H03K2017/9455 ,  H03K2217/94108 ,  H01L2924/00

Abstract: The internal propagation of radiation between a radiation source and radiation detector mounted within a sensor package is prevented by the use of an optical isolator. The optical isolator is formed by the combination of a baffle mounted between the source and detector and a groove formed in an upper surface of the sensor package between the source and detector. A bottom of the groove is positioned adjacent to an upper edge of the baffle.

Abstract translation: 通过使用光隔离器来防止辐射源和安装在传感器封装内的辐射探测器之间的辐射的内部传播。 光隔离器由安装在源和检测器之间的挡板和在源和检测器之间形成在传感器封装的上表面中的凹槽的组合形成。 凹槽的底部邻近挡板的上边缘定位。

公开(公告)号：US08098445B2

公开(公告)日：2012-01-17

申请号：US12013078

申请日：2008-01-11

Applicant: Colin Campbell ,  Eric Saugier

Inventor： Colin Campbell ,  Eric Saugier

IPC: G02B7/02

CPC classification number: G02B7/08

Abstract: A focusing device for a lens, including a frame, a lens carrier movable relative to the frame from a first position along an optical axis, a motor for driving the lens carrier along the optical axis, and at least one biasing member adapted to bias the lens carrier towards the first position. The biasing member may include one or more bending members.

Abstract translation: 一种用于透镜的聚焦装置，包括框架，可沿着光轴从第一位置相对于框架移动的透镜支架，用于沿着光轴驱动透镜支架的电动机以及至少一个偏置构件 透镜载体朝向第一位置。 偏置构件可以包括一个或多个弯曲构件。

公开(公告)号：US20100098074A1

公开(公告)日：2010-04-22

申请号：US12288672

申请日：2008-10-22

Applicant: Michael Kokernak ,  Madeleine Noland ,  Colin Campbell ,  Gordon Bechtel

Inventor： Michael Kokernak ,  Madeleine Noland ,  Colin Campbell ,  Gordon Bechtel

IPC: H04L12/28 ,  H04N7/10 ,  H04N7/173

CPC classification number: H04N7/17318 ,  H04N21/4622 ,  H04N21/4722 ,  H04N21/6118 ,  H04N21/6125 ,  H04N21/858

Abstract: The invention relates, in various aspects, to systems and methods for linking content stored on a computer network with content broadcast over a television network. The system includes a database, a trigger mechanism, a communications interface, and a packet generator. The database stores tokens representative of links to the stored content and delivery information representative of at least a duration for delivering the token. The trigger mechanism indicates an instruction to deliver a token over the television network, generating a signal indicating a respective one of the stored tokens and a time for starting the delivery of the respective token. The communications interface has a channel in communication with a television set box device for transferring the respective token to the television set box device. The packet generator generates packets within a stream of television content to be broadcast over the television network.

Abstract translation: 本发明在各个方面涉及用于将存储在计算机网络上的内容与通过电视网络广播的内容相关联的系统和方法。 该系统包括数据库，触发机制，通信接口和分组生成器。 数据库存储代表存储的内容的链接的代表和代表用于递送令牌的至少持续时间的递送信息。 触发机制指示在电视网络上传递令牌的指令，产生指示所存储的令牌中的相应一个的信号和用于开始相应令牌的发送的时间。 通信接口具有与电视机设备通信的通道，用于将相应的令牌传送到电视机设备。 分组生成器在电视内容流中生成要在电视网络上广播的分组。