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公开(公告)号：US08815499B2
公开(公告)日：2014-08-26
申请号：US13517250
申请日：2010-12-17
申请人： Björn Alriksson , Leif Jönsson , Sune Wännström
发明人： Björn Alriksson , Leif Jönsson , Sune Wännström
CPC分类号： C12P7/10 , C12N1/38 , C12P7/16 , C12P7/46 , C12P2203/00 , Y02E50/10 , Y02E50/16 , Y10S435/813
摘要： The present invention provides a method for decreasing the fermentation inhibition in a fermentation of cellulose-derived material in a fermentor, wherein fermentation inhibitory properties of the material subjected to fermentation is decreased by an addition of at least one reducing agent to the fermentor. Further, there is provided a method of increasing the fermentability of a fermentation process comprising the steps of measuring the fermentability of the fermentation process and if the fermentability is below a reference value, then adding at least one reducing agent to the fermentation process.
摘要翻译： 本发明提供一种用于降低发酵罐中纤维素衍生物质的发酵发酵抑制的方法，其中通过向发酵罐中加入至少一种还原剂来降低发酵物质的发酵抑制性能。 此外，提供了一种增加发酵方法的发酵能力的方法，包括以下步骤：测量发酵过程的发酵能力，如果发酵能力低于参考值，则在发酵过程中加入至少一种还原剂。
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公开(公告)号：US20130022958A1
公开(公告)日：2013-01-24
申请号：US13517250
申请日：2010-12-17
申请人： Björn Alriksson , Leif Jönsson , Sune Wännström
发明人： Björn Alriksson , Leif Jönsson , Sune Wännström
IPC分类号： C12Q3/00
CPC分类号： C12P7/10 , C12N1/38 , C12P7/16 , C12P7/46 , C12P2203/00 , Y02E50/10 , Y02E50/16 , Y10S435/813
摘要： The present invention provides a method for decreasing the fermentation inhibition in a fermentation of cellulose-derived material in a fermentor, wherein fermentation inhibitory properties of the material subjected to fermentation is decreased by an addition of at least one reducing agent to the fermentor. Further, there is provided a method of increasing the fermentability of a fermentation process comprising the steps of measuring the fermentability of the fermentation process and if the fermentability is below a reference value, then adding at least one reducing agent to the fermentation process.
摘要翻译： 本发明提供一种用于降低发酵罐中纤维素衍生物质的发酵发酵抑制的方法，其中通过向发酵罐中加入至少一种还原剂来降低发酵物质的发酵抑制性能。 此外，提供了一种增加发酵方法的发酵能力的方法，包括以下步骤：测量发酵过程的发酵能力，如果发酵能力低于参考值，则在发酵过程中加入至少一种还原剂。
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公开(公告)号：US08795997B2
公开(公告)日：2014-08-05
申请号：US13517284
申请日：2010-12-17
申请人： Leif Jönsson , Björn Alriksson , Adnan Cavka
发明人： Leif Jönsson , Björn Alriksson , Adnan Cavka
IPC分类号： C12P7/10
CPC分类号： C12P7/10 , C12N1/38 , C12P19/14 , C12P2203/00 , Y02E50/16
摘要： The present invention provides a method for decreasing the fermentation inhibition in a process for producing a target chemical from a pretreated cellulosic material, the process comprising enzymatic hydrolysis of the pretreated cellulosic material and fermentation of hydrolysed material, wherein the fermentation inhibitory properties of the material subjected to fermentation is decreased by an addition of at least one reducing agent to the pretreated material or hydrolysed material. Moreover, the present invention provides the use of dithionite for decreasing the fermentation inhibitory properties of a material being subjected to simultaneous enzymatic hydrolysis and fermentation.
摘要翻译： 本发明提供了一种降低由预处理的纤维素材料生产目标化学物质的方法中的发酵抑制的方法，该方法包括预处理的纤维素材料的酶水解和水解材料的发酵，其中所述材料的发酵抑制性质 通过向预处理的材料或水解材料中加入至少一种还原剂来降低发酵。 此外，本发明提供连二亚硫酸盐用于降低同时进行酶水解和发酵的材料的发酵抑制性质的用途。
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4.发明授权公开(公告)号：US09512454B2
公开(公告)日：2016-12-06
申请号：US14123556
申请日：2012-06-11
CPC分类号： C12P19/14 , C08B1/00 , C12P7/10 , C12P19/02 , C12P19/04 , C12P19/16 , C12P2201/00 , C12P2203/00 , Y02E50/16
摘要： The present invention relates to a method of enzymatic hydrolysis of a lignocellulosic material, comprising the steps of: a) pretreating the lignocellulosic material to obtain a slurry having a pH of less than 6; b) adding NaOH, Ca(OH)2 and/or CaO to the slurry to increase its pH to at least 8, said addition being carried out at a slurry temperature of at least 60° C.; c) reducing the pH of the slurry to below 7; and optionally cooling the slurry from step b) to a temperature below 60° C.; and d) adding hydrolytic enzymes to the slurry from c) and allowing the slurry to hydrolyze wherein no washing of the slurry is performed prior to step d).
摘要翻译： 本发明涉及木质纤维素材料的酶水解方法，包括以下步骤：a）预处理木质纤维素材料以获得pH小于6的浆料; b）向所述浆料中加入NaOH，Ca（OH）2和/或CaO以将其pH增加至至少8，所述加入在至少60℃的浆料温度下进行; c）将浆料的pH降低到7以下; 并任选地将来自步骤b）的浆料冷却至低于60℃的温度; 和d）从c）向浆液中加入水解酶，并允许浆料水解，其中在步骤d）之前不进行浆料的洗涤。
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公开(公告)号：US20130011894A1
公开(公告)日：2013-01-10
申请号：US13517284
申请日：2010-12-17
申请人： Leif Jönsson , Björn Alriksson , Adnan Cavka
发明人： Leif Jönsson , Björn Alriksson , Adnan Cavka
IPC分类号： C12P7/14
CPC分类号： C12P7/10 , C12N1/38 , C12P19/14 , C12P2203/00 , Y02E50/16
摘要： The present invention provides a method for decreasing the fermentation inhibition in a process for producing a target chemical from a pretreated cellulosic material, the process comprising enzymatic hydrolysis of the pretreated cellulosic material and fermentation of hydrolysed material, wherein the fermentation inhibitory properties of the material subjected to fermentation is decreased by an addition of at least one reducing agent to the pretreated material or hydrolysed material. Moreover, the present invention provides the use of dithionite for decreasing the fermentation inhibitory properties of a material being subjected to simultaneous enzymatic hydrolysis and fermentation.
摘要翻译： 本发明提供了一种降低由预处理的纤维素材料生产目标化学物质的方法中的发酵抑制的方法，该方法包括预处理的纤维素材料的酶水解和水解材料的发酵，其中所述材料的发酵抑制性质 通过向预处理的材料或水解材料中加入至少一种还原剂来降低发酵。 此外，本发明提供连二亚硫酸盐用于降低同时进行酶水解和发酵的材料的发酵抑制性质的用途。
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6.发明授权Fermentation process starting from cellulosic biomass and involving the recirculation of detoxified stillage into the process 有权发酵过程从纤维素生物质开始，并涉及将无毒废渣再循环到该过程中公开(公告)号：US08110383B2
公开(公告)日：2012-02-07
申请号：US13121611
申请日：2009-09-30
申请人： Leif Jönsson , Björn Alriksson
发明人： Leif Jönsson , Björn Alriksson
摘要： A method for preparing a target chemical derivable from cellulosic biomass, involving detoxification of spent hydrolysate is provided. The method comprises the steps of providing cellulosic biomass, subjecting the cellulosic biomass to aqueous pretreatment, aqueous hydrolysis, and fermentation under conditions in which at least a part of the fermentable sugars are fermented into a primary target chemical, separating the primary target chemical from the fermented hydrolysate to provide a spent hydrolysate comprising inhibitory substances and detoxifying the spent hydrolysate by decreasing the concentration of at least one of the inhibitory substances using a detoxification biocatalyst selected from the group consisting of wild type, mutant and recombinant filamentous fungi and recirculating at least a part of the detoxified spent hydrolysate, optionally after further purification.
摘要翻译： 提供了一种制备可从纤维素生物质衍生的目标化学物质的方法，涉及废水解产物的解毒。 该方法包括以下步骤：提供纤维素生物质，将纤维素生物质进行水性预处理，水解水解和发酵，其中至少一部分可发酵糖被发酵成主要目标化学品，将主要目标化学物质与 发酵的水解产物，以提供包含抑制物质的废水解产物，并通过使用选自野生型，突变型和重组丝状真菌的解毒生物催化剂，通过降低至少一种抑制物质的浓度来解毒废水解产物，并再循环至少一种 任选地在进一步纯化后的一部分解毒的废水解产物。
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7.发明申请FERMENTATION PROCESS STARTING FROM CELLULOSIC BIOMASS AND INVOLVING THE RECIRCULATION OF DETOXIFIED STILLAGE INTO THE PROCESS 有权发酵过程从细胞生物量开始并涉及到将过氧化还原酶再循环进入过程公开(公告)号：US20110217746A1
公开(公告)日：2011-09-08
申请号：US13121611
申请日：2009-09-30
申请人： Leif Jönsson , Björn Alriksson
发明人： Leif Jönsson , Björn Alriksson
摘要： A method for preparing a target chemical derivable from cellulosic biomass, involving detoxification of spent hydrolysate is provided. The method comprises the steps of providing cellulosic biomass, subjecting the cellulosic biomass to aqueous pretreatment, aqueous hydrolysis, and fermentation under conditions in which at least a part of the fermentable sugars are fermented into a primary target chemical, separating the primary target chemical from the fermented hydrolysate to provide a spent hydrolysate comprising inhibitory substances and detoxifying the spent hydrolysate by decreasing the concentration of at least one of the inhibitory substances using a detoxification biocatalyst selected from the group consisting of wild type, mutant and recombinant filamentous fungi and recirculating at least a part of the detoxified spent hydrolysate, optionally after further purification.
摘要翻译： 提供了一种制备可从纤维素生物质衍生的目标化学物质的方法，涉及废水解产物的解毒。 该方法包括以下步骤：提供纤维素生物质，将纤维素生物质进行水性预处理，水解水解和发酵，其中至少一部分可发酵糖被发酵成主要目标化学品，将主要目标化学物质与 发酵的水解产物，以提供包含抑制物质的废水解产物，并通过使用选自野生型，突变型和重组丝状真菌的解毒生物催化剂，通过降低至少一种抑制物质的浓度来解毒废水解产物，并再循环至少一种 任选地在进一步纯化后的一部分解毒的废水解产物。
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公开(公告)号：US07381551B2
公开(公告)日：2008-06-03
申请号：US10946654
申请日：2004-09-20
CPC分类号： C12N9/1205 , C12N9/0006 , C12P7/06 , C12P7/10 , Y02E50/16 , Y02E50/17
摘要： The present invention relates to a method for improved ethanol production from xylose utilizing strain of Saccharomyces cerevisiae comprising genes for overexpression of xylose reductase, xylitol dehydrogenase and xylulokinase, wherein in addition to said genes, one or more specific genes of a defined group is overexpressed, and/or one or more genes of a defined group is deleted.
摘要翻译： 本发明涉及利用酿酒酵母菌株改良木糖的乙醇生产方法，该方法包括木糖还原酶，木糖醇脱氢酶和木酮糖激酶过表达的基因，其中除所述基因外，定义的一个或多个特定基因被过表达， 和/或定义组的一个或多个基因被删除。
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